Protein Alignment CG13850 and FASTKD3

DIOPT Version :10

• Sequence 1: NP_651038.3
• Gene: CG13850 / 42630
• FlyBaseID: FBgn0038961
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_076996.2
• Gene: FASTKD3 / 79072
• HGNCID: 28758
• Length: 662
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 67/289 - (23%)
• Similarity: 109/289 - (37%)
• Gaps: 56/289 - (19%)

  Fly   298 ILESLTQWLLKNSEICRPQDLSAYFLTSALLNFKSAQLEEVSKKLVKSIVRE-DFTKQSEWLSFV 361
            ||.::.:..:..:|...|:.:||.......||:.......:.:||...:... ::......|..:
Human   388 ILNAVAETFVCQTEKFSPRQISALMEPFGKLNYLPPNASALFRKLENVLFTHFNYFPPKSLLKLL 452

  Fly   362 WSLTMLGLVEHGHLASVLSADFLETLKKDKAGVTATSKMRLLNLNSYAQLIATDYKGPLLPTDSP 426
            .|.::........||.:....||:.|:..::.:...|:.:|..|...:.|....||||.|   .|
Human   453 HSCSLNECHPVNFLAKIFKPLFLQRLQGKESHLDTLSRAQLTQLFLASVLECPFYKGPKL---LP 514

  Fly   427 VYQVPMAHPKAKQVLVNGMLDALKSLLPASNHLQTAVDT------KMGF--LIDALCHFDANKNP 483
            .|||                   ||.|.....|:|.||:      |:|.  |:.|..:| |.|..
Human   515 KYQV-------------------KSFLTPCCSLETPVDSQLYRYVKIGLTNLLGARLYF-APKVL 559

  Fly   484 LP----------LDKEN---PNAI------RVALMVIDFHDIC-HGTHRSG-SGVTNLTFDLLEK 527
            .|          ||:|.   |:..      |:||.:......| :..|..| ..:......||
Human   560 TPYCYTIDVEIKLDEEGFVLPSTANEDIHKRIALCIDGPKRFCSNSKHLLGKEAIKQRHLQLL-- 622

  Fly   528 SGYHVIPVPYNEFSTSDKLLKRVQYLESK 556
             ||.|:.:||:|........:.|:||:.|
Human   623 -GYQVVQIPYHEIGMLKSRRELVEYLQRK 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13850	NP_651038.3	TBRG4-like_N	32..293	CDD:467932
		FAST_1	318..387	CDD:461999	12/69 (17%)
		FAST_2	399..485	CDD:462448	26/93 (28%)
		RAP	498..556	CDD:214932	15/59 (25%)
FASTKD3	NP_076996.2	RESC6-like	129..457	CDD:480594	12/68 (18%)
		FAST_2	490..580	CDD:462448	30/112 (27%)
		RAP	593..650	CDD:214932	15/59 (25%)