DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13855 and Iqub

DIOPT Version :9

Sequence 1:	NP_651037.1	Gene:	CG13855 / 42629	FlyBaseID:	FBgn0038960	Length:	706	Species:	Drosophila melanogaster
Sequence 2:	NP_766123.2	Gene:	Iqub / 214704	MGIID:	3041159	Length:	788	Species:	Mus musculus

Alignment Length:	615	Identity:	186/615 - (30%)
Similarity:	293/615 - (47%)	Gaps:	81/615 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 NSTALDEFGIHEFQLEMNKEGREDQTSKLDLDVY------YDKHRL------ADFITVHISGDDT 164
            |:.:|.::||...::             :.::|:      |...|:      :..|||.|   .|
Mouse   179 NNESLIQYGIKPQEI-------------VQVEVFSTLPDQYPVRRIEGLSEGSQIITVTI---QT 227

  Fly   165 QDGQSKTVVVEIENAAIVKPFLCGYRDQKTGKEYLDAFTQTGPYFDKMKYRKYK------TRDTQ 223
            ...:.:.|.|||..:...||||.|:|.:.||.||.:|.|||.|       ||..      .||||
Mouse   228 SIDRYEEVAVEIIKSDFHKPFLGGFRHKITGLEYHNAGTQTVP-------RKIPEKDNLFCRDTQ 285

  Fly   224 TWEQKEKTLNTAHEQSVQCHLDGINILYVSAANDFTIVPGKYQTFAQKERAERKLEKILLIQRNW 288
            |..||:|...|.:..|.|....|:   |||...|..:.||.|  |:..|...|:|..:::||.::
Mouse   286 TVFQKKKLQQTTNTTSTQMTKIGV---YVSNMTDKLLKPGNY--FSAAEYHARRLHAVIVIQTSY 345

  Fly   289 RRWILWKYIH-LRAQEYRRLVQNREHEDERYEKCVEQ-RMERHRVIKQFPRNKDDFDLLYAEVAR 351
            |||...:|:. ||.|:..||....|.|..:.::..|. ||:.:|  :..|:..:||:|||..:..
Mouse   346 RRWHAKRYVESLRKQKKLRLEWEEEQELLKIQEKEEWIRMDYYR--RHNPKTTEDFELLYNALEL 408

  Fly   352 WKKAELKRITANYEGPA-RIAEVNILLDKEIQLLNGVERQRNLVYKAMEDFRKDQLLKEMGKPIE 415
            |::.|:::| .:|...| |.|.:..||:||.|::..:.|.|:......:|......|.:...|..
Mouse   409 WRQEEVEQI-CHYSSEAERKAALCELLEKETQMIASIGRHRSAARMERQDAAIQAFLDKCSAPNV 472

  Fly   416 WVGYKDSKIHMDLLSTQRVRFLTEIYK-DLRKPRSKEDRLDFIRQVMAVLTEETCFPHFPELFDL 479
            |.......|.||...|.|.|.|..||| .|.|..|:::|||.:..:...:.|..| ....|:.:|
Mouse   473 WRRGDGKTIEMDTQFTIRARELQSIYKCILLKDLSQDERLDILLTLKHTVKEHEC-KLTQEILEL 536

  Fly   480 FDREKNLLLY-AKSFDVEILRKRQTMLFFDLIKFQKGEPK----QRIPS---------RMCIVCK 530
            .|||.:|::. .|..::|.||||.|.||...||.....|:    .::|.         ..|..|:
Mouse   537 IDREVDLMMRGVKPHNLEGLRKRITTLFIHYIKTPLFNPEVAKYLKVPQDPLKFYDTIYFCHSCQ 601

  Fly   531 KVKTYAEFAIRTRQSHVDTCKHCYYLKLTATENTV--------YQSILRCIHRDERKRKCTTSFA 587
            ......||::......|..|:||..|     ||..        |:.:|:.::..|......:..|
Mouse   602 NYLPSVEFSVSPTSHRVYRCRHCINL-----ENETQRRESFLKYKCLLQRLYYSEADYGDNSQIA 661

  Fly   588 FVMQPDDVRHIIDKIWHGHSALSKTENLSELRLPRWNKSDDWAPWNCICLTERETRDHYKIDDIE 652
            |:||..|::::.:.||...||||..::|::|.:.||:|..:|:|||||.||:.|:..|.::..||
Mouse   662 FLMQLQDIKYLTENIWASQSALSAWDDLNDLVMVRWDKHVEWSPWNCILLTKDESTAHLRLPSIE 726

  Fly   653 KVYDPKFVLHIGNLHMLARSLFHTLAAVAT 682
            |.|...||..|.:.|:||::.|..:..:|:
Mouse   727 KGYGHHFVHKIKHKHILAKNYFSQIPTLAS 756

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region
CG13855	NP_651037.1	None
Iqub	NP_766123.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..89
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833981
Domainoid	1	1.000	229	1.000	Domainoid score	I2460
eggNOG	1	0.900	-	-		E1_28JBT
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H44790
Inparanoid	1	1.050	230	1.000	Inparanoid score	I3438
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52016
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006949
OrthoInspector	1	1.000	-	-		oto92163
orthoMCL	1	0.900	-	-		OOG6_104169
Panther	1	1.100	-	-	LDO	PTHR21074
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5373
SonicParanoid	1	1.000	-	-		X5043
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790