DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18596 and mrm3b

DIOPT Version :9

Sequence 1:	NP_651031.1	Gene:	CG18596 / 42622	FlyBaseID:	FBgn0038953	Length:	1136	Species:	Drosophila melanogaster
Sequence 2:	NP_001157404.1	Gene:	mrm3b / 792923	ZFINID:	ZDB-GENE-030131-158	Length:	449	Species:	Danio rerio

Alignment Length:	223	Identity:	41/223 - (18%)
Similarity:	85/223 - (38%)	Gaps:	55/223 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   897 PTSVSDCILMMTNAPFDENISFISCSYDFRMKLKRALE-------------TFKRKQSVLIPELA 948
            ||.:|:.::..|:....::.:.|:.:.|     |.::|             :...:|.|:.....
Zfish    47 PTEISEGVISQTSERSSQHNNDITRNTD-----KSSIENPVSPNNSQPVQFSHINRQKVINLTSR 106

  Fly   949 TSLAALNGNVQRKMNPVGDIYPESDFVVSNKARDDHELI-----VVASLIDKLPNLGGLARTCEV 1008
            |....::|.:..|::|......:...:..:|...:|:::     :|.|.:|    .|..|:|...
Zfish   107 TRFGEVDGLLYEKLHPGDKSLAKLARIAGSKKLREHQVVLEGKHLVCSALD----AGAEAQTLYF 167

  Fly  1009 LGVNTLILGLKSQAEKSDFTNLSMTAEKTLNILEVNPESLAGFLLEKQMEGYKIVGAEQTAHSTN 1073
            ..|:.|             ..|.:...:..|:::|            :||..::.....|:....
Zfish   168 SSVDAL-------------RELPLDKLRQTNVVKV------------KMEDAQVWSELDTSQEII 207

  Fly  1074 FVDFKFPKKSILLLGHEKHG--IPANLI 1099
            .: ||.|:.|.|....||:|  :|..||
Zfish   208 AI-FKRPEASRLTFSEEKYGRAVPLTLI 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18596	NP_651031.1	SpoU_methylase	986..1128	CDD:278985	25/121 (21%)
mrm3b	NP_001157404.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	52..90		5/42 (12%)
		SpoU	131..444	CDD:223640	27/134 (20%)
		SpoU_sub_bind	146..211	CDD:214943	14/94 (15%)
		SpoU_methylase	230..435	CDD:278985	3/5 (60%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	311..334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0566
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900