DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18596 and Tarbp1

DIOPT Version :9

Sequence 1:NP_651031.1 Gene:CG18596 / 42622 FlyBaseID:FBgn0038953 Length:1136 Species:Drosophila melanogaster
Sequence 2:XP_038954215.1 Gene:Tarbp1 / 679346 RGDID:1589526 Length:1581 Species:Rattus norvegicus


Alignment Length:1264 Identity:294/1264 - (23%)
Similarity:486/1264 - (38%) Gaps:342/1264 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    53 LALKRVLQC---IHNLLQTNSK--YNVRFG------PKVFHKLVSVVIADSREDSASRR--QLVA 104
            |||:.||||   .|.:|...:.  |.::..      .||....||..:...|::.:..|  ||..
  Rat   471 LALRDVLQCTMITHQVLLRGAAQCYLLQAAMRLVDVEKVSLSDVSAFLMSLRQEESLGRGTQLWT 535

  Fly   105 NLL--VCVQLHIRKFPRIEAKFVLQQLWSLSQSNERQPHAAQILVHLFDDFVNNLGTECAQELLV 167
            .|.  :||          ..::..|.  |:..|:..:......:.:|..:||.:.|.|       
  Rat   536 ELCDWLCV----------NERYFKQS--SIGGSDGHEASLNAYVKNLVQEFVKSPGWE------- 581

  Fly   168 LTRNLLQSDVRDDRRSAYFLMHKLQEIDEVLAALQCSEVQWSAYVGIMENLEEQQ--SHLVLPTL 230
                          :.:.|:...|:.....|..|...:|:     ||.....|:|  .:::...|
  Rat   582 --------------KESSFVPDWLEARLTALMVLLAVDVK-----GIKTKFREKQRTQNVLRIFL 627

  Fly   231 STLLPRMGLMSNNLSEDWLDWLRI-----LCIRLL----------GDNNILVLRW----TLKYFL 276
            ...|..:|.:..|.   ::..||.     |.:|||          .|:.:....|    :....:
  Rat   628 DPWLDALGKLGTNA---YMPLLRTDRCLQLLVRLLHSCVPRGSSAQDDEVSAALWASVMSAAESV 689

  Fly   277 SHFSLEQISRFNLLTQFLAATNRTQLYNPEVPDCLTKQQITDFSAQFPAEILLEAL--VCVPWHA 339
            |.|.|.:::...|  |.:|..:|.|||...:.:.::.|....:.|..|...::..|  .||    
  Rat   690 SQFVLRRLTMNEL--QDVADLDRCQLYLTVLAELVSLQVKLGWKAGNPVSRVISPLRNACV---- 748

  Fly   340 VPLIHWLQAWELKQLPVVSKELLFKLG-ARVRSL-----QNPVLRGEAINYVIFSLSATIDSLSL 398
                |.||..|.:|.|.:|.::...:. |.:.:|     ::|||:.::                 
  Rat   749 ----HHLQEAEGRQEPTLSHQVQTAVSMATLAALCEAEDRHPVLQPDS----------------- 792

  Fly   399 GDYLLFMESLYNTIDRYQSHSQLAQKIRNCSNLEKHIASFNIRCCELVSQMDYKHDVFVAFLEKL 463
                    |....:||:.|...|.:.::     :.|....:|..|.|.:...::..         
  Rat   793 --------SSAEAVDRFLSALPLNRMLQ-----KPHSEGQSIGVCPLENGSVFEES--------- 835

  Fly   464 RTVPKSKHGWWRLLPIFLHRELDHPEQYLDFYRSVYDLDTSFL-----------ESGV------S 511
                .|..||.:::..:||      :|::..         |||           ||.|      :
  Rat   836 ----SSSQGWGKVVAQYLH------DQWVCL---------SFLLRKHQGLIPATESDVLKCCLPA 881

  Fly   512 LEQMQQHLLNRLDCQTREEKSFVLEHSVDLFVQINLPTWSKLEVLNLNPLELLDRGTEETFATLS 576
            :|.....|.:.||..|......|            ||.:..:|||....|.     :|||....|
  Rat   882 VEMPVPTLQSALDVLTVLPAGLV------------LPVFHCMEVLVPKLLT-----SEETLCIES 929

  Fly   577 ------NILSTHDEQLADQNVLPAFISRLGKLKVRETQAILKYAVQNLSSEEYEKCVVDVLEKNT 635
                  .|.|..:.||.....|.||:..:...::....|.||    ..:.::.::.:..::|.::
  Rat   930 FDVAWKMISSLSNTQLTFWPNLKAFVHFVFNNEILTIAAKLK----GPAYDKIKEIMCKMIEMSS 990

  Fly   636 FLLGTMD------CEEYIKAPT-----SF---------VIKRMLQGETTTGDAR----IERAFEQ 676
            ...|..:      |:.::.|.:     ||         |::..:.|.....|.|    ::...|.
  Rat   991 IKSGVFNILICYCCQSWLAAASGVAQGSFSSAKDYSELVLEACVFGTVFRRDQRLIQDVQTFIEN 1055

  Fly   677 ISDTGAMD-------------RVQFIQYAKNSTGLDIS---FICD---DLLRMNNELSRKKPRYF 722
            :....|.:             |:..|::.....|.|:|   |:.|   .||..:...||.:.||.
  Rat  1056 LGQGCAANIILENTKREDYYVRICVIKFLCLLDGSDVSHKLFLEDLAVKLLDKDESASRSRTRYH 1120

  Fly   723 ANCKEHRMKMRIGKALLDLSDRWKWS------DNLWEAVLCPSDQPNISFMYEYLVSKMLPSIDL 781
            .|..:||:|.|:.:.||.|...:..:      |.::.|.. .::|.:|.:..|:|:..:|.....
  Rat  1121 ENSLQHRVKNRVWQTLLVLFPAFDQNFLHGIIDKVFHAGF-TNNQASIKYFIEWLIILILHKFPE 1184

  Fly   782 LL-----------EQLKL-LATLKPSQQISLVSVVHIYCLTRWESIQHEQLV--EVFAVLLPLTM 832
            .|           |::|. :.|.     :|::|.:.|..    ::|..::||  :...|.|...:
  Rat  1185 FLPKFWACFSYGEEKIKTSICTF-----LSVLSHLDIIV----QNIPEKKLVLKQALTVALQWCL 1240

  Fly   833 GANFQTRLLAQLVLHRICSECEDRSIQMPIADALKKSIKVTLSEKLTEFQCEARLLLPELGKQCP 897
            ..||..||.|.:.|.:....|  :::|.....|....|:.:||      |.|:........|.. 
  Rat  1241 SHNFSVRLYALVALKKAWHLC--KALQFEECGAWTTVIECSLS------QAESMHGAGNARKNW- 1296

  Fly   898 TSVSDCILMMTNAPFDENISFISCSYDFRMKLKRALETFKRKQSVL---------------IPEL 947
            ..:.|.....|..|..:            ..|:....||.|...|.               ||..
  Rat  1297 QRIQDHFFFSTFHPLKD------------YSLETIFYTFPRLSGVTEEEWIALEKFANFTDIPSN 1349

  Fly   948 ATSLAALNG------------------------------NVQRKMNPVGDIYPESDFVV------ 976
            ..|...|:|                              :||:|:.|.|....:||..:      
  Rat  1350 VGSQWYLSGITLGELSPGDWSQQDQGSTLGEADSQSEWADVQKKIIPWGHSALDSDLELEFQDRA 1414

  Fly   977 SNKARDDHELIVVASLIDKLPNLGGLARTCEVLGVNTLILGLKSQAEKSDFTNLSMTAEKTLNIL 1041
            :...:....||||||||||..|||||.|||||.|...|::|.........|.:||::||:.|.::
  Rat  1415 AKLGKSISRLIVVASLIDKPTNLGGLCRTCEVFGAAVLVVGSLQCVSDRQFQHLSVSAEQWLPLV 1479

  Fly  1042 EVNPESLAGFLLEKQMEGYKIVGAEQTAHSTNFVDFKFPKKSILLLGHEKHGIPANLIGFLDYAV 1106
            ||.|..|..:|.:|:.|||.::|.||||.|::...::||:||:||||:|:.|||.|||..||..|
  Rat  1480 EVRPSQLVDYLQQKKAEGYTVIGVEQTAQSSDLAQYRFPEKSLLLLGNEREGIPVNLIQQLDVCV 1544

  Fly  1107 EIPQYGLVRSLNVHVAGSLFIWEYCKQHL 1135
            ||||.|::|||||||:|:|.||||.:|.|
  Rat  1545 EIPQQGIIRSLNVHVSGALLIWEYTRQQL 1573

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18596NP_651031.1 SpoU_methylase 986..1128 CDD:278985 76/141 (54%)
Tarbp1XP_038954215.1 cytochrome_P450 3..>227 CDD:425388
SpoU-like_TRM3-like 1424..1568 CDD:349964 78/143 (55%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 156 1.000 Domainoid score I4101
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 237 1.000 Inparanoid score I3299
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D171334at2759
OrthoFinder 1 1.000 - - FOG0002756
OrthoInspector 1 1.000 - - oto98009
orthoMCL 1 0.900 - - OOG6_102883
Panther 1 1.100 - - LDO PTHR12029
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X4127
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
1110.970

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