Protein Alignment CG18596 and Tarbp1

DIOPT Version :10

• Sequence 1: NP_651031.1
• Gene: CG18596 / 42622
• FlyBaseID: FBgn0038953
• Length: 1136
• Species: Drosophila melanogaster
• Sequence 2: XP_038954215.2
• Gene: Tarbp1 / 679346
• RGDID: 1589526
• Length: 1579
• Species: Rattus norvegicus
• Alignment Length: 1264
• Identity: 294/1264 - (23%)
• Similarity: 486/1264 - (38%)
• Gaps: 342/1264 - (27%)

  Fly    53 LALKRVLQC---IHNLLQTNSK--YNVRFG------PKVFHKLVSVVIADSREDSASRR--QLVA 104
            |||:.||||   .|.:|...:.  |.::..      .||....||..:...|::.:..|  ||..
  Rat   469 LALRDVLQCTMITHQVLLRGAAQCYLLQAAMRLVDVEKVSLSDVSAFLMSLRQEESLGRGTQLWT 533

  Fly   105 NLL--VCVQLHIRKFPRIEAKFVLQQLWSLSQSNERQPHAAQILVHLFDDFVNNLGTECAQELLV 167
            .|.  :||          ..::..|.  |:..|:..:......:.:|..:||.:.|.|
  Rat   534 ELCDWLCV----------NERYFKQS--SIGGSDGHEASLNAYVKNLVQEFVKSPGWE------- 579

  Fly   168 LTRNLLQSDVRDDRRSAYFLMHKLQEIDEVLAALQCSEVQWSAYVGIMENLEEQQ--SHLVLPTL 230
                          :.:.|:...|:.....|..|...:|:     ||.....|:|  .:::...|
  Rat   580 --------------KESSFVPDWLEARLTALMVLLAVDVK-----GIKTKFREKQRTQNVLRIFL 625

  Fly   231 STLLPRMGLMSNNLSEDWLDWLRI-----LCIRLL----------GDNNILVLRW----TLKYFL 276
            ...|..:|.:..|.   ::..||.     |.:|||          .|:.:....|    :....:
  Rat   626 DPWLDALGKLGTNA---YMPLLRTDRCLQLLVRLLHSCVPRGSSAQDDEVSAALWASVMSAAESV 687

  Fly   277 SHFSLEQISRFNLLTQFLAATNRTQLYNPEVPDCLTKQQITDFSAQFPAEILLEAL--VCVPWHA 339
            |.|.|.:::...|  |.:|..:|.|||...:.:.::.|....:.|..|...::..|  .||
  Rat   688 SQFVLRRLTMNEL--QDVADLDRCQLYLTVLAELVSLQVKLGWKAGNPVSRVISPLRNACV---- 746

  Fly   340 VPLIHWLQAWELKQLPVVSKELLFKLG-ARVRSL-----QNPVLRGEAINYVIFSLSATIDSLSL 398
                |.||..|.:|.|.:|.::...:. |.:.:|     ::|||:.::
  Rat   747 ----HHLQEAEGRQEPTLSHQVQTAVSMATLAALCEAEDRHPVLQPDS----------------- 790

  Fly   399 GDYLLFMESLYNTIDRYQSHSQLAQKIRNCSNLEKHIASFNIRCCELVSQMDYKHDVFVAFLEKL 463
                    |....:||:.|...|.:.::     :.|....:|..|.|.:...::..
  Rat   791 --------SSAEAVDRFLSALPLNRMLQ-----KPHSEGQSIGVCPLENGSVFEES--------- 833

  Fly   464 RTVPKSKHGWWRLLPIFLHRELDHPEQYLDFYRSVYDLDTSFL-----------ESGV------S 511
                .|..||.:::..:||      :|::..         |||           ||.|      :
  Rat   834 ----SSSQGWGKVVAQYLH------DQWVCL---------SFLLRKHQGLIPATESDVLKCCLPA 879

  Fly   512 LEQMQQHLLNRLDCQTREEKSFVLEHSVDLFVQINLPTWSKLEVLNLNPLELLDRGTEETFATLS 576
            :|.....|.:.||..|......|            ||.:..:|||....|.     :|||....|
  Rat   880 VEMPVPTLQSALDVLTVLPAGLV------------LPVFHCMEVLVPKLLT-----SEETLCIES 927

  Fly   577 ------NILSTHDEQLADQNVLPAFISRLGKLKVRETQAILKYAVQNLSSEEYEKCVVDVLEKNT 635
                  .|.|..:.||.....|.||:..:...::....|.||    ..:.::.::.:..::|.::
  Rat   928 FDVAWKMISSLSNTQLTFWPNLKAFVHFVFNNEILTIAAKLK----GPAYDKIKEIMCKMIEMSS 988

  Fly   636 FLLGTMD------CEEYIKAPT-----SF---------VIKRMLQGETTTGDAR----IERAFEQ 676
            ...|..:      |:.::.|.:     ||         |::..:.|.....|.|    ::...|.
  Rat   989 IKSGVFNILICYCCQSWLAAASGVAQGSFSSAKDYSELVLEACVFGTVFRRDQRLIQDVQTFIEN 1053

  Fly   677 ISDTGAMD-------------RVQFIQYAKNSTGLDIS---FICD---DLLRMNNELSRKKPRYF 722
            :....|.:             |:..|::.....|.|:|   |:.|   .||..:...||.:.||.
  Rat  1054 LGQGCAANIILENTKREDYYVRICVIKFLCLLDGSDVSHKLFLEDLAVKLLDKDESASRSRTRYH 1118

  Fly   723 ANCKEHRMKMRIGKALLDLSDRWKWS------DNLWEAVLCPSDQPNISFMYEYLVSKMLPSIDL 781
            .|..:||:|.|:.:.||.|...:..:      |.::.|.. .::|.:|.:..|:|:..:|.....
  Rat  1119 ENSLQHRVKNRVWQTLLVLFPAFDQNFLHGIIDKVFHAGF-TNNQASIKYFIEWLIILILHKFPE 1182

  Fly   782 LL-----------EQLKL-LATLKPSQQISLVSVVHIYCLTRWESIQHEQLV--EVFAVLLPLTM 832
            .|           |::|. :.|.     :|::|.:.|..    ::|..::||  :...|.|...:
  Rat  1183 FLPKFWACFSYGEEKIKTSICTF-----LSVLSHLDIIV----QNIPEKKLVLKQALTVALQWCL 1238

  Fly   833 GANFQTRLLAQLVLHRICSECEDRSIQMPIADALKKSIKVTLSEKLTEFQCEARLLLPELGKQCP 897
            ..||..||.|.:.|.:....|  :::|.....|....|:.:||      |.|:........|..
  Rat  1239 SHNFSVRLYALVALKKAWHLC--KALQFEECGAWTTVIECSLS------QAESMHGAGNARKNW- 1294

  Fly   898 TSVSDCILMMTNAPFDENISFISCSYDFRMKLKRALETFKRKQSVL---------------IPEL 947
            ..:.|.....|..|..:            ..|:....||.|...|.               ||..
  Rat  1295 QRIQDHFFFSTFHPLKD------------YSLETIFYTFPRLSGVTEEEWIALEKFANFTDIPSN 1347

  Fly   948 ATSLAALNG------------------------------NVQRKMNPVGDIYPESDFVV------ 976
            ..|...|:|                              :||:|:.|.|....:||..:
  Rat  1348 VGSQWYLSGITLGELSPGDWSQQDQGSTLGEADSQSEWADVQKKIIPWGHSALDSDLELEFQDRA 1412

  Fly   977 SNKARDDHELIVVASLIDKLPNLGGLARTCEVLGVNTLILGLKSQAEKSDFTNLSMTAEKTLNIL 1041
            :...:....||||||||||..|||||.|||||.|...|::|.........|.:||::||:.|.::
  Rat  1413 AKLGKSISRLIVVASLIDKPTNLGGLCRTCEVFGAAVLVVGSLQCVSDRQFQHLSVSAEQWLPLV 1477

  Fly  1042 EVNPESLAGFLLEKQMEGYKIVGAEQTAHSTNFVDFKFPKKSILLLGHEKHGIPANLIGFLDYAV 1106
            ||.|..|..:|.:|:.|||.::|.||||.|::...::||:||:||||:|:.|||.|||..||..|
  Rat  1478 EVRPSQLVDYLQQKKAEGYTVIGVEQTAQSSDLAQYRFPEKSLLLLGNEREGIPVNLIQQLDVCV 1542

  Fly  1107 EIPQYGLVRSLNVHVAGSLFIWEYCKQHL 1135
            ||||.|::|||||||:|:|.||||.:|.|
  Rat  1543 EIPQQGIIRSLNVHVSGALLIWEYTRQQL 1571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18596	NP_651031.1	SpoU-like_TRM3-like	986..1130	CDD:349964	78/143 (55%)
Tarbp1	XP_038954215.2	None