Protein Alignment CG18596 and tarbp1

DIOPT Version :10

• Sequence 1: NP_651031.1
• Gene: CG18596 / 42622
• FlyBaseID: FBgn0038953
• Length: 1136
• Species: Drosophila melanogaster
• Sequence 2: XP_001921874.4
• Gene: tarbp1 / 566303
• ZFINID: ZDB-GENE-090313-346
• Length: 1579
• Species: Danio rerio
• Alignment Length: 1567
• Identity: 347/1567 - (22%)
• Similarity: 577/1567 - (36%)
• Gaps: 517/1567 - (32%)

  Fly    21 VETYIQNQ----NLLGEIAELDDMLYDLVSMHKDNELALKRVLQCIHNLLQTNSKYN---VRFGP 78
            ::|.::::    |||..:..|..:   .|::.:.:::. :::||.:..:|.|....|   .|...
Zfish    71 IQTILRSEDGGKNLLNAVCGLFAV---CVNVCQSSDVP-EQILQALLPVLMTKDDANHEANRADI 131

  Fly    79 KVFHKLVSVVIADSREDSASRRQLVANLLVCVQLHIRKFPRIEAKFVLQQLWSLSQSNERQPHAA 143
            :|..:.:.|:::....|.:...:.:::.|.||: |:.  ..|.:|.:: ::|.....:..:...:
Zfish   132 EVAIEAIGVLLSSISNDRSIISRTLSSTLNCVK-HLS--DSIISKIIV-RIWFTMLKSCGEDAES 192

  Fly   144 QILVHLFDDFV-----NNLGTECAQELLVLTR---NLLQSDVR----DDRRSAYF-------LMH 189
            ::|:.::||.:     :...|...:.||.||.   :|..|:..    |.|||..|       |.|
Zfish   193 EVLLQIWDDLLRWHQRDQTDTASTRVLLCLTALSDHLCSSETSPNRPDPRRSQRFFRAVQDGLTH 257

  Fly   190 ----------------------KLQEI--------DEVLAALQCSEVQ-----WSAYVGIMENLE 219
                                  |.:|:        ||:|......:.:     |..|..::|.||
Zfish   258 RDSVTRKRALYLLTRCVSLAEMKKEEVVSIEEHETDEILFRWTPDKQKLLREFWEDYALVLETLE 322

  Fly   220 EQQSHLVLPTLSTLLPRMGLMSNNLSED---------WLDWLRILCI--RLLGDNNILVLRWTLK 273
            |.|.|::.|.|:    |:.::....:.|         ||     ||:  |:....|..|::..:.
Zfish   323 ENQIHVIRPVLN----RIDMLVETTTTDIQGGLFSPSWL-----LCVYQRMFHSENKAVMKEGVH 378

  Fly   274 YFLSHFSLEQISRFNLLTQF-----LAATNRTQLYN-------PEVPDCLTKQQI--TDFSAQFP 324
            :.|...:|.|.:.....:||     :.....:.||:       .:.|:...|.||  .:|....|
Zfish   379 HLLQLKALHQPAFALAFSQFVIGPLMDVLAESSLYHRAPQQNIRDCPELGVKLQIFMVNFFNSLP 443

  Fly   325 AE-------ILLEALVCVPWHAVPLIHWLQAWE-LKQLPVVSKELL--FKLGARVRSLQNPV-LR 378
            .|       .|::.|....|.||||:...||.. |...|::..:.|  |:...|...:.:.| ||
Zfish   444 EENRGSVLLRLIQRLGSRQWCAVPLLFLSQALSCLAPCPLLGSDGLQAFREVLRCTMITHQVLLR 508

  Fly   379 GEA---INYVIFSLSATIDSLSLGDYLLFMESLYNTIDRYQSHSQLAQKIRNCSNLEKHIASF-- 438
            |.:   :.:..|.|: .:.::||.:...|:           .|.:..:.:...:.|.|.:..:
Zfish   509 GASQCFLLHAAFCLT-DVSAVSLDEIFAFL-----------VHFRADESLCRGTALWKELCKWLQ 561

  Fly   439 -NIRCCELVSQMDYKHD------------VFVAFLEKLRT-------------VP---------- 467
             |..|..|.|......|            ||....:||:|             :|
Zfish   562 VNEGCFGLASGASGSDDLPSEYPNGDGAAVFTYTQQKLKTFLTVSANSDQTGGLPDPAEAELLAR 626

  Fly   468 -----------KSKHGWWRLL--PIF--LHR----------ELDHPEQ------YLDFYRSVYDL 501
                       ||:.....||  |:.  |||          :.|...|      :|...||...|
Zfish   627 AVLLTADLQQMKSEEPALDLLLQPLLDVLHRLSTNVYLLLHKTDRSLQLLLRLLHLHVKRSETQL 691

  Fly   502 DTS------FLESGV--SLEQMQQHLLNRL--------DCQTREEKSFVLEHSVDLFVQIN---- 546
            :.:      .|::.|  .:|.:|:.||.||        |.|..|....||...:..|..::
Zfish   692 EDTEDVVAVVLKTHVLSVVESVQEFLLRRLTGELKELCDLQRSELYLSVLRELIFTFSTVSWYSS 756

  Fly   547 ------LPTWSK--LEVLN-------------LNPLELL----DRGTEET--------------F 572
                  ||..:|  |.:||             :..|.||    ||....|              |
Zfish   757 NLQQNYLPKLTKHCLRILNEPSEQNQVQRAVSMATLALLCDVADRSVLNTQSVAMGSLRSLRQYF 821

  Fly   573 ATLSNILSTHDEQ-----------------------------LADQNVLPAFISRL-GKLKVRET 607
            ...|:..|.|..|                             :.||....:|:.|. |.|:|.|.
Zfish   822 YPSSSSSSLHLNQSLQKPTAVAISHPEDSVVLKDWGRVVAQFIRDQWTCLSFLQRSDGTLQVPEA 886

  Fly   608 QAILKYAVQNLS------------------SEEYEKC--------------VVDVLEKN------ 634
            ..:|:.||:.|:                  .::..:|              ||..|..|
Zfish   887 AEVLREAVEALALLPGHLVLPVLDFMSSVLPQQMVQCEESLCVEAICASWKVVQALSTNPHDFWS 951

  Fly   635 ------------TFLLGTMDCEEYIKAPTSFVIKRML---------------------------Q 660
                        ..|..|.:.:..|.|....|:|.::                           |
Zfish   952 TLQAFVRLAFHQQLLQLTEEQKPRITACIQQVLKELMELAQVRSGVFNVVIQHCCETWLPSDGVQ 1016

  Fly   661 GETTTGDA------------------RIERAFEQI------------SDTGAMDRVQFIQYAKNS 695
            .:|....|                  |.:|..:::            ::|.....|:..|:.:..
Zfish  1017 SDTVFSSALLHLNILTEACVYGPVFRRDQRLVQEVQSYVEQLGERCAANTAVSSDVRDDQFPRVC 1081

  Fly   696 TGLDISFIC--------------DDLLRMNN---ELSRKKPRYFANCKEHRMKMRIGKALLDLSD 743
            .   ::|:|              :.:|||.|   |:|:.|.||::|..:||:|.|..:.||.|..
Zfish  1082 V---LAFLCRLDPSHHLHQRLMEELVLRMLNKDAEISKSKVRYYSNSIQHRVKSRAWQTLLLLLH 1143

  Fly   744 RWKWSDNLWEAVL---C----PSDQPNISFMYEY---LVSKMLPS-IDLLLEQLKLLATLKPSQQ 797
            :.: .:.:.|.||   |    .|:|.::.::.|:   ||.:..|| |..|.....|......:..
Zfish  1144 QLR-DEFVSECVLSRVCEAGFSSNQASVKYLIEWTLILVLQRSPSHIQSLWNCFSLDHEKTKTSI 1207

  Fly   798 ISLVSV-VHIYCL---TRWESIQHEQLVEVFAVLLPLTMGANFQTRLLAQLVLHRICSECEDRSI 858
            .:.:|| ||:..|   ...:::|..:.||   |.|......||..||.|.|.|.|:. |.:|..:
Zfish  1208 CTFLSVLVHLNVLLPKLADKAVQWRRAVE---VSLQWCFSHNFSVRLYALLALKRVW-ELQDAHV 1268

  Fly   859 QM-PIADALKKSIKVTLSEKLTEFQCEARLLLPELGKQCPTSVSDCILMMTNAPFDENISFISCS 922
            .: .....|...:|..|.      |.||   :...|.           .|.|....:...|.|..
Zfish  1269 FIEEDLGGLSTVVKACLE------QAEA---MQNTGN-----------AMKNWSRIQEHFFFSVF 1313

  Fly   923 YDFR-MKLKRALETFKRKQSVLIPELA----------------------------TSLAALN--- 955
            :..| ..::...:.|.|     :.|:|                            |.|:.|.
Zfish  1314 HPIRDYSIETIFQIFPR-----LSEMAEDEWLPLWKFESFVDFPTNSALPLNNPGTDLSELQPGD 1373

  Fly   956 ---------------GNVQRKMNP----VGDIYPESDFVVSNKA----RDDHELIVVASLIDKLP 997
                           ..||:|::|    |.:..||  .:...:|    :....|:||||||||..
Zfish  1374 WIQQDKGDLELEERWAEVQKKISPWKLSVQEQEPE--LMAQQRALRLGKLTSSLLVVASLIDKPT 1436

  Fly   998 NLGGLARTCEVLGVNTLILGLKSQAEKSDFTNLSMTAEKTLNILEVNPESLAGFLLEKQMEGYKI 1062
            |||||.||||:.|...|:|..........|..||:::|..|.::||.|..|:.||..|:.|||.:
Zfish  1437 NLGGLCRTCEIFGAKALVLDSLRHVNDKQFQALSVSSELWLPMMEVKPAELSDFLQLKKSEGYWV 1501

  Fly  1063 VGAEQTAHSTNFVDFKFPKKSILLLGHEKHGIPANLIGFLDYAVEIPQYGLVRSLNVHVAGSLFI 1127
            :|.|||::|.:..|:.||:||:||||:|:.|||||::..||..|||||:|:.|||||||:.:|.:
Zfish  1502 IGVEQTSNSQSLQDYTFPEKSLLLLGNEREGIPANVLQLLDVCVEIPQFGVTRSLNVHVSAALLV 1566

  Fly  1128 WEYCKQH 1134
            |||.:||
Zfish  1567 WEYTRQH 1573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18596	NP_651031.1	SpoU-like_TRM3-like	986..1130	CDD:349964	73/143 (51%)
tarbp1	XP_001921874.4	SpoU-like_TRM3-like	1425..1569	CDD:349964	73/143 (51%)