Protein Alignment CG7069 and pykA

DIOPT Version :10

• Sequence 1: NP_651030.1
• Gene: CG7069 / 42621
• FlyBaseID: FBgn0038952
• Length: 744
• Species: Drosophila melanogaster
• Sequence 2: NP_416368.1
• Gene: pykA / 946527
• ECOCYCID: EG10803
• Length: 480
• Species: Escherichia coli
• Alignment Length: 477
• Identity: 161/477 - (33%)
• Similarity: 240/477 - (50%)
• Gaps: 49/477 - (10%)

  Fly     3 VVRMNFSHGSHEYHCQTIQAARKAIAMYVEQTGLPRTLAIALDTKGPEIRTGKLAGGNDRAEIEL 67
            ||||||||||.|.|.......|:..|.      |.|.:||..|.:||:||......|    ::.|
E. coli    34 VVRMNFSHGSPEDHKMRADKVREIAAK------LGRHVAILGDLQGPKIRVSTFKEG----KVFL 88

  Fly    68 KTGDKVTLSTKKEMADKSNKDNIYVDYQRLPQLVKPGNRVFVDDGLIALIVKESKGDEVICQVEN 132
            ..|||..|.......: .:|:.:.:||:.||..|.||:.:.:|||.:.|.|.|.:|.:|..:|..
E. coli    89 NIGDKFLLDANLGKGE-GDKEKVGIDYKGLPADVVPGDILLLDDGRVQLKVLEVQGMKVFTEVTV 152

  Fly   133 GGKLGSHKGINLPGVPVDLPSVTEKDKQDLKFGAEQKVDMIFASFIRDANALKEIRQVLGPAGAC 197
            ||.|.::||||..|..:...::|||||.|:|..|...||.:..||.|....|...|::...||..
E. coli   153 GGPLSNNKGINKLGGGLSAEALTEKDKADIKTAALIGVDYLAVSFPRCGEDLNYARRLARDAGCD 217

  Fly   198 IKIISKIENHQGLVN---IDDIIRESDGIMVARGDMGIEIPTEDVPLAQKSIVAKCNKVGKPVIC 259
            .||::|:|..:.:.:   :||||..||.:||||||:|:||...::...||:::.:..::.:.||.
E. coli   218 AKIVAKVERAEAVCSQDAMDDIILASDVVMVARGDLGVEIGDPELVGIQKALIRRARQLNRAVIT 282

  Fly   260 ATQMMESMTNKPRPTRAEASDVANAIFDGCDAVMLSGETAKGKYPVECVQCMARICAKVEAV--- 321
            ||||||||...|.|||||..|||||:.||.||||||.|||.|:||.|.|..|||:|...|.:
E. coli   283 ATQMMESMITNPMPTRAEVMDVANAVLDGTDAVMLSAETAAGQYPSETVAAMARVCLGAEKIPSI 347

  Fly   322 --------LWYESLQNSLKREIRTSAADHISAVTTAIAEAATVGQARAIVVASPCSMVAQMVSHM 378
                    :.:::::.::... ...||:|:..||             ||:..:.....|.|.|.:
E. coli   348 NVSKHRLDVQFDNVEEAIAMS-AMYAANHLKGVT-------------AIITMTESGRTALMTSRI 398

  Fly   379 RPPCPIVMLTGNESEAAQSLLFRGIYPLLVEE----MVIGSFNFRRIMQSGLKLMGKMDILEPGQ 439
            ....||..::.:|.....:.|:||:.|:..:.    :...|.....:...|..:.|.:.|:..|.
E. coli   399 SSGLPIFAMSRHERTLNLTALYRGVTPVHFDSANDGVAAASEAVNLLRDKGYLMSGDLVIVTQGD 463

  Fly   440 KGSVVLVNAMSAEKITFRLFTI 461
            ..|.|      ....|.|:.|:
E. coli   464 VMSTV------GSTNTTRILTV 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7069	NP_651030.1	Pyruvate_Kinase	1..410	CDD:453956	151/420 (36%)
		PTZ00121	<462..>741	CDD:173412	161/477 (34%)
pykA	NP_416368.1	PRK05826	3..469	CDD:235619	158/465 (34%)