DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7069 and AT5G63680

DIOPT Version :9

Sequence 1:	NP_651030.1	Gene:	CG7069 / 42621	FlyBaseID:	FBgn0038952	Length:	744	Species:	Drosophila melanogaster
Sequence 2:	NP_001331216.1	Gene:	AT5G63680 / 836488	AraportID:	AT5G63680	Length:	510	Species:	Arabidopsis thaliana

Alignment Length:	474	Identity:	196/474 - (41%)
Similarity:	284/474 - (59%)	Gaps:	36/474 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRVVRMNFSHGSHEYHCQTIQAARKAIAMYVEQTGLPRTLAIALDTKGPEIRTGKLAGGNDRAEI 65
            |.|.|.||||||||||.:|:...|.|    ::.||:  ..|:.|||||||||||.|..||   .|
plant    46 MNVARFNFSHGSHEYHQETLDNLRTA----MQNTGI--LAAVMLDTKGPEIRTGFLKDGN---PI 101

  Fly    66 ELKTGDKVTLSTKKEMADKSNKDNIYVDYQRLPQLVKPGNRVFVDDGLIALIVK--ESKGDEVIC 128
            :||.|.::|::|..::  |.::..|.:.|::||..|||||.:...||.|:|.|.  :.....|||
plant   102 QLKEGQEITITTDYDI--KGDEKTISMSYKKLPVDVKPGNTILCADGSISLAVVSCDPNAGTVIC 164

  Fly   129 QVENGGKLGSHKGINLPGVPVDLPSVTEKDKQD-LKFGAEQKVDMIFASFIRDANALKEIRQVLG 192
            :.||...||..|.:|||||.||||::|:||.:| ||:|....:|||..||:|..:.|..:|:|||
plant   165 RCENTAMLGERKNVNLPGVVVDLPTLTDKDVEDILKWGVPNNIDMIALSFVRKGSDLVNVRKVLG 229

  Fly   193 PAGACIKIISKIENHQGLVNIDDIIRESDGIMVARGDMGIEIPTEDVPLAQKSIVAKCNKVGKPV 257
            .....|.::||:||.:|::|.|:|:||:|..||||||:|:|||.|.:.||||.::.|||..||||
plant   230 SHSKSIMLMSKVENQEGVLNFDEILRETDAFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPV 294

  Fly   258 ICATQMMESMTNKPRPTRAEASDVANAIFDGCDAVMLSGETAKGKYPVECVQCMARICAKVEAVL 322
            :.||||:|||...||||||||:|||||:.||.|.||||||:|.|.||...|:.||:||.:.|:.|
plant   295 VTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAYPEIAVKTMAKICIEAESSL 359

  Fly   323 WYESLQNSLKREIRTS--AADHISAVTTAIAEAATVGQARAIVVASPCSMVAQMVSHMRPPCPIV 385
            .|.::   .|..||.:  ....:.::.::....|...:|:.|:|.:.....|::|:..||..||:
plant   360 DYNTI---FKEMIRATPLPMSTLESLASSAVRTANKAKAKLIIVLTRGGTTAKLVAKYRPAVPIL 421

  Fly   386 MLT-------------GNESEAAQSLLFRGIYPLLVE--EMVIGSFNFRRIMQSGLKLMGKMDIL 435
            .:.             .:||.|..||::||:.|:|.|  .....|.:...|::|.||...:..:.
plant   422 SVVVPVFTSDTFNWSCSDESPARHSLIYRGLIPVLGEGSAKATDSESTEEIIESALKSATEKGLC 486

  Fly   436 EPGQKGSVVLVNAMSAEKI 454
            ..|.  :||.::.:.|..:
plant   487 NHGD--AVVALHRIGAASV 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7069	NP_651030.1	PRK05826	1..446	CDD:235619	195/464 (42%)
CG7069	NP_651030.1	Pyruvate_Kinase	1..410	CDD:304951	187/428 (44%)
AT5G63680	NP_001331216.1	PLN02461	1..510	CDD:215255	196/474 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	354	1.000	Domainoid score	I209
eggNOG	1	0.900	-	-		E1_COG0469
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	410	1.000	Inparanoid score	I455
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D933620at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1077
orthoMCL	1	0.900	-	-		OOG6_100258
Panther	1	1.100	-	-	O	PTHR11817
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X374
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.830