Protein Alignment CG7069 and PyK

DIOPT Version :10

• Sequence 1: NP_651030.1
• Gene: CG7069 / 42621
• FlyBaseID: FBgn0038952
• Length: 744
• Species: Drosophila melanogaster
• Sequence 2: NP_524448.3
• Gene: PyK / 42620
• FlyBaseID: FBgn0267385
• Length: 533
• Species: Drosophila melanogaster
• Alignment Length: 468
• Identity: 264/468 - (56%)
• Similarity: 330/468 - (70%)
• Gaps: 14/468 - (2%)

  Fly     1 MRVVRMNFSHGSHEYHCQTIQAARKAIAMYVEQTGLPRTLAIALDTKGPEIRTGKLAGGNDRAEI 65
            |.:.||||||||||||..|:...|:|:..|..:.|....:|||||||||||||| |.||:..|||
  Fly    72 MNIARMNFSHGSHEYHAATVANVRQAVKNYSAKLGYEHPVAIALDTKGPEIRTG-LIGGSGTAEI 135

  Fly    66 ELKTGDKVTLSTKKEMADKSNKDNIYVDYQRLPQLVKPGNRVFVDDGLIALIVKESKGDEVICQV 130
            |||.|:|:.|:|.||..:|.:.:.:||||:.:..:||||||||||||||:|||:|...|.:.|:|
  Fly   136 ELKKGEKIKLTTNKEFLEKGSLEIVYVDYENIVNVVKPGNRVFVDDGLISLIVREVGKDSLTCEV 200

  Fly   131 ENGGKLGSHKGINLPGVPVDLPSVTEKDKQDLKFGAEQKVDMIFASFIRDANALKEIRQVLGPAG 195
            ||||.|||.||:||||||||||:|:||||.||.||.||:||||||||||:|.||.|||:|||..|
  Fly   201 ENGGSLGSRKGVNLPGVPVDLPAVSEKDKSDLLFGVEQEVDMIFASFIRNAAALTEIRKVLGEKG 265

  Fly   196 ACIKIISKIENHQGLVNIDDIIRESDGIMVARGDMGIEIPTEDVPLAQKSIVAKCNKVGKPVICA 260
            ..|||||||||.||:.|:|:||...|||||||||:|||||.|.|.||||:::|:|||.|||||||
  Fly   266 KNIKIISKIENQQGMHNLDEIIEAGDGIMVARGDLGIEIPAEKVFLAQKAMIARCNKAGKPVICA 330

  Fly   261 TQMMESMTNKPRPTRAEASDVANAIFDGCDAVMLSGETAKGKYPVECVQCMARICAKVEAVLWYE 325
            |||:|||..||||||||.||||||:.||.|.||||||||||:||:|||..||:.|.:.||.||::
  Fly   331 TQMLESMVKKPRPTRAEISDVANAVLDGADCVMLSGETAKGEYPLECVLTMAKTCKEAEAALWHQ 395

  Fly   326 SLQNSLKREIRTSAADHISAVTTAIAEAATVGQARAIVVASPCSMVAQMVSHMRPPCPIVMLTGN 390
            :|.|.|.|...|..|.|.:|:  |..||||..:|.||||.:.....|..||..||.|||:.:|..
  Fly   396 NLFNDLVRGAGTIDASHAAAI--AAVEAATKAKASAIVVITTSGKSAFQVSKYRPRCPIIAVTRF 458

  Fly   391 ESEAAQSLLFRGIYPLLVEEMVIGSF----NFRRIMQSGLKLMGKMDILEPGQKGSVVLVNAM-- 449
            ...|.|:.|:||:.||:.:|..:|.:    :.|  :|.||::..|...::.|.  |||:|...
  Fly   459 AQTARQAHLYRGLVPLIYKEPGLGDWLKDVDVR--VQFGLQVGKKNGFIKTGD--SVVVVTGWKQ 519

  Fly   450 -SAEKITFRLFTI 461
             |....|.|:.|:
  Fly   520 GSGFTNTIRIVTV 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7069	NP_651030.1	Pyruvate_Kinase	1..410	CDD:453956	248/408 (61%)
		PTZ00121	<462..>741	CDD:173412	264/468 (56%)
PyK	NP_524448.3	Pyruvate_Kinase	46..532	CDD:238178	263/466 (56%)