Protein Alignment CG7069 and CG7362

DIOPT Version :10

• Sequence 1: NP_651030.1
• Gene: CG7069 / 42621
• FlyBaseID: FBgn0038952
• Length: 744
• Species: Drosophila melanogaster
• Sequence 2: NP_650388.2
• Gene: CG7362 / 41787
• FlyBaseID: FBgn0038258
• Length: 793
• Species: Drosophila melanogaster
• Alignment Length: 753
• Identity: 366/753 - (48%)
• Similarity: 458/753 - (60%)
• Gaps: 140/753 - (18%)

  Fly     1 MRVVRMNFSHGSHEYHCQTIQAARKAIAMYVEQTGLPRTLAIALDTKGPEIRTGKLAGGNDRAEI 65
            |:|||::||.|:|:.|||.|||||||||||.|:|||||:||||||||||.|.
  Fly    59 MKVVRLDFSDGTHDCHCQAIQAARKAIAMYAEETGLPRSLAIALDTKGPVIN------------- 110

  Fly    66 ELKTGDKVTLSTKKEMADKSNKDNIYVDYQRLPQLVKPGNRVFVDDGLIALIVKESKGDEVICQV 130
                                            ||
  Fly   111 --------------------------------PQ------------------------------- 112

  Fly   131 ENGGKLGSHKGINLPGVPVDLPSVTEKDKQDLKFGAEQKVDMIFASFIRDANALKEIRQVLG--P 193
                           ||..||.::||:||.||||||:||||||||||||||.|||||||.||  |
  Fly   113 ---------------GVAADLNAITEQDKLDLKFGADQKVDMIFASFIRDAKALKEIRQALGACP 162

  Fly   194 AGACIKIISKIENHQGLVNIDDIIRESDGIMVARGDMGIEIPTEDVPLAQKSIVAKCNKVGKPVI 258
            :...||||||||:.|.|.|||:|||||||||||.|:||.||..|.||||||||||||||||||||
  Fly   163 SSEHIKIISKIESQQALANIDEIIRESDGIMVALGNMGNEIALEAVPLAQKSIVAKCNKVGKPVI 227

  Fly   259 CATQMMESMTNKPRPTRAEASDVANAIFDGCDAVMLSGETAKGKYPVECVQCMARICAKVEAVLW 323
            ||.|||.||..||||||||:|||||||.|||||::||.|||||||||:|||||||||||||:|||
  Fly   228 CANQMMNSMITKPRPTRAESSDVANAILDGCDALVLSDETAKGKYPVQCVQCMARICAKVESVLW 292

  Fly   324 YESLQNSLKREIRTSAADHISAVTTAIAEAATVGQARAIVVASPCSMVAQMVSHMRPPCPIVMLT 388
            |||:||:||.|:|.:||||||||:|||||||||.||:|||||||||:|:||||.||||||||:||
  Fly   293 YESIQNNLKSEVRINAADHISAVSTAIAEAATVSQAQAIVVASPCSIVSQMVSQMRPPCPIVLLT 357

  Fly   389 GNESEAAQSLLFRGIYPLLVEEMVIGSFNFRRIMQSGLKLMGKMDILEPGQKGSVVLVNAMSAEK 453
            |...||||||||||:|||||:|||.||.|:.||||||||::.|:|||:.||:|::||||||||:|
  Fly   358 GCPHEAAQSLLFRGVYPLLVKEMVYGSVNYCRIMQSGLKILAKLDILKAGQRGTLVLVNAMSADK 422

  Fly   454 ITFRLFTIRQQTKEERDQDERCRKLALEQSCKERAEKEECRKLQQAEECQKQKLAKKCKQFEEKQ 518
            :||||||..|.|:.|| ::|||||||.:|.|||.:..:.|..
  Fly   423 LTFRLFTFAQPTEAER-EEERCRKLARKQRCKEMSVNKSCPN----------------------- 463

  Fly   519 KVCPKKNDTP---KNDCPKKDCPKKECPKQDDEISKCRQM----QEAEAEERKCKEEFEQMCKLA 576
               ||.:.:.   |:|.......|||.|| |:|:|||.|:    |:...|:....:|.|.:|...
  Fly   464 ---PKSSKSEISIKSDEKDGTSSKKEFPK-DEEVSKCLQLENEIQQKRGEDSVMNKENENLCHNV 524

  Fly   577 EEKRKEAEKCRKADEERRKEEAEKCRKLEEDRKCK--LAEEKKRNEEELKIIEAEVAKLEAAEKA 639
            ..|....:..|:|..|...::.||.:|.|:.||..  |.:...|.:::.|..:::  |.:.:..
  Fly   525 ALKCLHLKNERQAQSEAMMKQTEKLKKAEDPRKNNGTLKDSFNRKKKDDKTSKSD--KKDGSSS- 586

  Fly   640 KRLKEEEKKKEELMKCKQRNEAKKKREEAE-RCKRKERERELAEMEN-KWKQVAEKRKRKKAAEM 702
               |::....:|:.||.||::.....||.| .|.:|.:|....:.|. |..|:.::|:.:..|||
  Fly   587 ---KKDRPNHKEVWKCLQRSQDLVMAEENEYLCSKKSKECPNKDDEALKCLQLKKQRQARAEAEM 648

  Fly   703 CRKIEDAKEKAAAESADKILKAVCEKLKQSLSDPDKSK 740
            .:|.|..|..:.:...:......|.|||:  ..|.|:|
  Fly   649 KKKAELKKNNSLSHKKEDDKAPNCNKLKK--QGPKKNK 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7069	NP_651030.1	Pyruvate_Kinase	1..410	CDD:453956	251/410 (61%)
		PTZ00121	<462..>741	CDD:173412	79/290 (27%)
CG7362	NP_650388.2	Pyruvate_Kinase	35..407	CDD:453956	269/438 (61%)
		PTZ00121	<476..>791	CDD:173412	60/218 (28%)