Protein Alignment CG7069 and pyk-2

DIOPT Version :9

• Sequence 1: NP_651030.1
• Gene: CG7069 / 42621
• FlyBaseID: FBgn0038952
• Length: 744
• Species: Drosophila melanogaster
• Sequence 2: NP_001255515.1
• Gene: pyk-2 / 177984
• WormBaseID: WBGene00014001
• Length: 515
• Species: Caenorhabditis elegans
• Alignment Length: 464
• Identity: 223/464 - (48%)
• Similarity: 295/464 - (63%)
• Gaps: 29/464 - (6%)

  Fly     1 MRVVRMNFSHGSHEYHCQTIQAARKAIAMYVEQTGLPRTLAIALDTKGPEIRTGKLAGGNDRAEI 65
            |.:.|:|||||:||.|..||:..|:|    .|....|  :||||||||||||||..|  |:..|:
 Worm    60 MNIARLNFSHGTHEAHAATIKTIREA----AENAPFP--VAIALDTKGPEIRTGMFA--NNMKEV 116

  Fly    66 ELKTGDKVTLSTKKEMADKSNKDNIYVDYQRLPQLVKPGNRVFVDDGLIALIVKESKGDEVICQV 130
            :|:.|..|.:||...|...:...:||.||:.||::|:||:|:::|||||:|||:..:...|||.:
 Worm   117 QLENGKSVRVSTDPSMEFAATSSHIYADYRNLPKVVQPGSRIYIDDGLISLIVESCEETAVICTI 181

  Fly   131 ENGGKLGSHKGINLPGVPVDLPSVTEKDKQDLKFGAEQKVDMIFASFIRDANALKEIRQVLGPAG 195
            ||||.||:.||:||||..||||:||.||.:||.||.||.||:|||||||:|:.:.:||||||..|
 Worm   182 ENGGALGTRKGVNLPGTIVDLPAVTSKDIEDLLFGVEQGVDIIFASFIRNADGIHKIRQVLGEKG 246

  Fly   196 ACIKIISKIENHQGLVNIDDIIRESDGIMVARGDMGIEIPTEDVPLAQKSIVAKCNKVGKPVICA 260
            ..|.||:|||:..|:.|.|:||..|||:||||||:|||||.|.|.||||.::||||..|||||||
 Worm   247 KHIYIIAKIESEDGVTNCDEIIEASDGVMVARGDLGIEIPAEKVFLAQKMLIAKCNLAGKPVICA 311

  Fly   261 TQMMESMTNKPRPTRAEASDVANAIFDGCDAVMLSGETAKGKYPVECVQCMARICAKVEAVLWY- 324
            |||:|||..||||||||.||||||:.||.|.||||||||||.||||.:..|..||.:.|:..::
 Worm   312 TQMLESMITKPRPTRAECSDVANAVLDGVDCVMLSGETAKGDYPVEALAIMHNICKEAESAFFHM 376

  Fly   325 ESLQNSLKREIRTSAADHISAVTTAIAE-AATVG-QARAIVVASPCSMVAQMVSHMRPPCPIVML 387
            :..:..:....:.:...|    |||||. :||:. :|.||::.:.....|::.|..|||.||:.:
 Worm   377 KHFEELILHTKKPTGMTH----TTAIAAVSATITCRAVAIILITTTGKTARLCSRYRPPVPIITV 437

  Fly   388 TGNESEAAQSLLFRGIYPLL------------VEEMVIGSFNFRRIMQSGLKLMGKMDILEPGQK 440
            :.:|..:.|..|.|||:|:.            |||.|....|..:  ..|...:|...|:..|.|
 Worm   438 SRDERISRQLHLHRGIFPVYYPKGRIDEWDVDVEERVQYGVNLGK--TRGFIHLGDPLIVITGWK 500

  Fly   441 GSVVLVNAM 449
            ......|.|
 Worm   501 QGAGFTNTM 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7069	NP_651030.1	PRK05826	1..446	CDD:235619	221/459 (48%)
		Pyruvate_Kinase	1..410	CDD:304951	212/423 (50%)
pyk-2	NP_001255515.1	Pyruvate_Kinase	34..514	CDD:238178	223/464 (48%)
		pyruv_kin	34..511	CDD:273424	223/464 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D219692at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100258
Panther	1	1.100	-	-	O	PTHR11817
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X374
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920