DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PyK and AT5G56350

DIOPT Version :9

Sequence 1:	NP_524448.3	Gene:	PyK / 42620	FlyBaseID:	FBgn0267385	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_200446.1	Gene:	AT5G56350 / 835735	AraportID:	AT5G56350	Length:	498	Species:	Arabidopsis thaliana

Alignment Length:	501	Identity:	231/501 - (46%)
Similarity:	318/501 - (63%)	Gaps:	31/501 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 IVCTIGPASSSVEMLEKMMATGMNIARMNFSHGSHEYHAATVANVRQAVKNYSAKLGYEHPVAIA 114
            ||||:||||.||.|:||::..|||:||.||||||||||..|:.|:.||:.|....      .|:.
plant    12 IVCTLGPASRSVPMVEKLLRAGMNVARFNFSHGSHEYHQETLDNLHQAMLNTGIL------CAVM 70

  Fly   115 LDTKGPEIRTGLIGGSGTAEIELKKGEKIKLTTNKEFLEKGSLEIVYVDYENIVNVVKPGNRVFV 179
            |||||||||||.:  .....|:||:|::|.::|:.:.  ||....:.:.|:.:...|.||..:..
plant    71 LDTKGPEIRTGFL--KDGKPIQLKQGQEITISTDYDL--KGDENTICMSYKKLAVDVNPGMVILC 131

  Fly   180 DDGLISLIVREVGKDSLT--CEVENGGSLGSRKGVNLPGVPVDLPAVSEKDKSDLL-FGVEQEVD 241
            .||.|||:|....|::.|  |..||...||.||.||||||.||||.::||||.|:: :||..::|
plant   132 ADGTISLLVLSCDKENGTVRCRCENSAMLGERKNVNLPGVVVDLPTLTEKDKEDIMQWGVPNQID 196

  Fly   242 MIFASFIRNAAALTEIRKVLGEKGKNIKIISKIENQQGMHNLDEIIEAGDGIMVARGDLGIEIPA 306
            ||..||:|..:.|.::||:||:..|||.::||:|||:|:.|.|:|:...|..|:||||||:|||.
plant   197 MIALSFVRKGSDLVQVRKLLGKHAKNILLMSKVENQEGVANFDDILVNSDAFMIARGDLGMEIPI 261

  Fly   307 EKVFLAQKAMIARCNKAGKPVICATQMLESMVKKPRPTRAEISDVANAVLDGADCVMLSGETAKG 371
            ||:|||||.||.:||..||||:.||||||||:|.|||||||.:|||||||||.||||||||||.|
plant   262 EKIFLAQKVMIYKCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAG 326

  Fly   372 EYPLECVLTMAKTCKEAEAALWHQNLFNDLVRGAGT-IDASHAAAIAAVEAATKAKASAIVVITT 435
            .||...|.||||.|.|||:.|.:.::|..::..:.. :....:.|.:||..|..|:|:.|:|:|.
plant   327 AYPELAVRTMAKICVEAESTLDYGDVFKRIMLYSPVPMSPLESLASSAVRTANSARATLIMVLTR 391

  Fly   436 SGKSAFQVSKYRPRCPIIAV------TRF-------AQTARQAHLYRGLVPLIYKEPGLGDWLKD 487
            .|.:|..|:||||..||::|      |.|       ...||.:.::|||:|::|.........:.
plant   392 GGSTARLVAKYRPGMPILSVVVPEIKTDFFDWSCSDESPARHSLIFRGLIPVLYAGSARASHDES 456

  Fly   488 VDVRVQFGLQVGKKNGFIKTGDSVVVVTGWKQGSGFTNTIRIVTVE 533
            .:..::|..|.||:....|||||||.:.    ..|..:.|:|:||:
plant   457 TEEAIEFATQYGKEKELCKTGDSVVALL----RVGNASVIKILTVK 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PyK	NP_524448.3	Pyruvate_Kinase	46..532	CDD:238178	229/498 (46%)
PyK	NP_524448.3	pyruv_kin	46..529	CDD:273424	228/495 (46%)
AT5G56350	NP_200446.1	PLN02461	2..498	CDD:215255	230/499 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	354	1.000	Domainoid score	I209
eggNOG	1	0.900	-	-		E1_COG0469
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	410	1.000	Inparanoid score	I455
OMA	1	1.010	-	-		QHG53565
OrthoDB	1	1.010	-	-		D933620at2759
OrthoFinder	1	1.000	-	-		FOG0000841
OrthoInspector	1	1.000	-	-		mtm1077
orthoMCL	1	0.900	-	-		OOG6_100258
Panther	1	1.100	-	-	O	PTHR11817
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X374
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840