DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PyK and AT4G26390

DIOPT Version :9

Sequence 1:	NP_524448.3	Gene:	PyK / 42620	FlyBaseID:	FBgn0267385	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_194369.1	Gene:	AT4G26390 / 828745	AraportID:	AT4G26390	Length:	497	Species:	Arabidopsis thaliana

Alignment Length:	501	Identity:	230/501 - (45%)
Similarity:	320/501 - (63%)	Gaps:	31/501 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 IVCTIGPASSSVEMLEKMMATGMNIARMNFSHGSHEYHAATVANVRQAVKNYSAKLGYEHPVAIA 114
            ||||:||||.||.|:||::..||::||.||||||:|||..|:.|:|||:.|....      .|:.
plant    11 IVCTLGPASRSVPMVEKLLMAGMSVARFNFSHGSYEYHQETLDNLRQAMLNTGML------CAVM 69

  Fly   115 LDTKGPEIRTGLIGGSGTAEIELKKGEKIKLTTNKEFLEKGSLEIVYVDYENIVNVVKPGNRVFV 179
            |||||||||||.:  .....|:||:|::|.::|:.:.  ||..:.:.:.|:.:...|.||..:..
plant    70 LDTKGPEIRTGFL--KDGKPIQLKQGQEITISTDYDL--KGDEKTICMSYKKLAQDVNPGMVILC 130

  Fly   180 DDGLISLIVREVGKD--SLTCEVENGGSLGSRKGVNLPGVPVDLPAVSEKDKSDLL-FGVEQEVD 241
            .||.|||.|....|:  ::.|..||...||.||.||||||.||||.::||||.|:| :||..::|
plant   131 ADGTISLKVLSCDKEKGTVRCRCENTSMLGERKNVNLPGVVVDLPTLTEKDKQDILEWGVPNQID 195

  Fly   242 MIFASFIRNAAALTEIRKVLGEKGKNIKIISKIENQQGMHNLDEIIEAGDGIMVARGDLGIEIPA 306
            ||..||:|..:.|.::||:||:..|.|.::||:|||:|:.|.|:|:...|..|:||||||:|||.
plant   196 MIALSFVRKGSDLVQVRKLLGKHAKTILLMSKVENQEGVANFDDILINSDAFMIARGDLGMEIPI 260

  Fly   307 EKVFLAQKAMIARCNKAGKPVICATQMLESMVKKPRPTRAEISDVANAVLDGADCVMLSGETAKG 371
            ||:|||||.||.:||..||||:.||||||||:|.|||||||.:|||||||||.||||||||||.|
plant   261 EKIFLAQKVMIYKCNFMGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAG 325

  Fly   372 EYPLECVLTMAKTCKEAEAALWHQNLFND-LVRGAGTIDASHAAAIAAVEAATKAKASAIVVITT 435
            .||...|.||||.|.|||:.|.:.::|.. ::..|..:....:.|.:||..||.::|:.::|:|.
plant   326 AYPELAVRTMAKICVEAESTLDYGDIFKRIMLHAAVPMSPMESLASSAVRTATSSRATLMMVLTR 390

  Fly   436 SGKSAFQVSKYRPRCPIIAVTRFAQT-------------ARQAHLYRGLVPLIYKEPGLGDWLKD 487
            .|.:|..|:||||..||::|.....|             ||.:.:||||||::|.........:.
plant   391 GGSTARLVAKYRPGIPILSVVVPEITSDSFDWACSNEAPARHSLIYRGLVPVLYAGSARASIDES 455

  Fly   488 VDVRVQFGLQVGKKNGFIKTGDSVVVVTGWKQGSGFTNTIRIVTVE 533
            .:..::|..:.|||....|||||||.:  ::.|:..  .|:|:||:
plant   456 TEETLEFASEYGKKKQLCKTGDSVVAL--FRTGNAI--VIKILTVK 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PyK	NP_524448.3	Pyruvate_Kinase	46..532	CDD:238178	228/498 (46%)
PyK	NP_524448.3	pyruv_kin	46..529	CDD:273424	227/495 (46%)
AT4G26390	NP_194369.1	PLN02461	1..497	CDD:215255	229/499 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	354	1.000	Domainoid score	I209
eggNOG	1	0.900	-	-		E1_COG0469
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	410	1.000	Inparanoid score	I455
OMA	1	1.010	-	-		QHG53565
OrthoDB	1	1.010	-	-		D933620at2759
OrthoFinder	1	1.000	-	-		FOG0000841
OrthoInspector	1	1.000	-	-		mtm1077
orthoMCL	1	0.900	-	-		OOG6_100258
Panther	1	1.100	-	-	O	PTHR11817
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X374
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840