DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PyK and AT3G55650

DIOPT Version :9

Sequence 1:	NP_524448.3	Gene:	PyK / 42620	FlyBaseID:	FBgn0267385	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_191124.1	Gene:	AT3G55650 / 824731	AraportID:	AT3G55650	Length:	510	Species:	Arabidopsis thaliana

Alignment Length:	509	Identity:	224/509 - (44%)
Similarity:	309/509 - (60%)	Gaps:	43/509 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 IVCTIGPASSSVEMLEKMMATGMNIARMNFSHGSHEYHAATVANVRQAVKNYSAKLGYEHPVAIA 114
            |:||:||.|.||||:||::..|||:||.|||||||.||..|:.|:|.|:.|....      .|:.
plant    20 IICTLGPVSRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDNTGIL------SAVM 78

  Fly   115 LDTKGPEIRTGLIGGSGTAEIELKKGEKIKLTTNKEFLEKGSLEIVYVDYENIVNVVKPGNRVFV 179
            |||||||||||.:  .....|:|.:|::|  |.:.:::.:|...::.:.|:.:...||||:.:..
plant    79 LDTKGPEIRTGFL--KEGKPIQLNQGQEI--TISIDYMIEGDSNVISMSYKKLAEDVKPGDVILC 139

  Fly   180 DDGLISLIVREVGKD--SLTCEVENGGSLGSRKGVNLPGVPVDLPAVSEKDKSDLL-FGVEQEVD 241
            .||.|||.|....|.  .:.|..||...||.||.|||||:.||||.::||||.|:: :||..::|
plant   140 SDGTISLTVLSCDKSFGLVRCRCENSAILGERKNVNLPGIVVDLPTLTEKDKEDIIQWGVPNKID 204

  Fly   242 MIFASFIRNAAALTEIRKVLGEKGKNIKIISKIENQQGMHNLDEIIEAGDGIMVARGDLGIEIPA 306
            :|..||:|..:.|||:|::|||..|||.::||:|||:|:.|.::|:|..|..||||||||:|||.
plant   205 IIALSFVRKGSDLTEVRRLLGEHSKNIMLMSKVENQEGVMNCEKILENSDAFMVARGDLGMEIPI 269

  Fly   307 EKVFLAQKAMIARCNKAGKPVICATQMLESMVKKPRPTRAEISDVANAVLDGADCVMLSGETAKG 371
            ||:|||||.||...|..||||:.||||||||...|||||||.:|||||||||.||||||||||.|
plant   270 EKMFLAQKTMIKMANALGKPVVTATQMLESMTVSPRPTRAEATDVANAVLDGTDCVMLSGETAAG 334

  Fly   372 EYPLECVLTMAKTCKEAEAALWHQNLFNDLVRGAGTIDASHAAAIAA--VEAATKAKASAIVVIT 434
            .:|...||||::.|||||..: ..::.:....|..::..|...::||  |..|....||||||:|
plant   335 AHPEAAVLTMSRICKEAEDFI-DYDILHKKTLGMVSLPLSPIESLAASVVSTAQSVFASAIVVLT 398

  Fly   435 TSGKSAFQVSKYRPRCPIIAV----------------TRFAQTARQAHLYRGLVPLIYKEPGLGD 483
            ..|.:|..|:||||..||::|                ...|..||:..:||.::|::.......|
plant   399 KGGYTAELVAKYRPSVPILSVIVPEIAQGNDMEMSCSDSVAHAARRGLIYRRIIPVVATGSSARD 463

  Fly   484 WLKD-VDVRVQFGLQVGKKNGFIKTGDSVVV---VTGWKQGSGFTNTIRIVTVE 533
            ..|| .:..:...:...|..|..|.|||:|.   :.|       ::.::|||||
plant   464 SNKDATEEMINLAIGFAKTKGICKNGDSIVALHKIDG-------SSVVKIVTVE 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PyK	NP_524448.3	Pyruvate_Kinase	46..532	CDD:238178	221/506 (44%)
PyK	NP_524448.3	pyruv_kin	46..529	CDD:273424	219/503 (44%)
AT3G55650	NP_191124.1	PLN02461	1..510	CDD:215255	222/507 (44%)
AT3G55650	NP_191124.1	Pyruvate_Kinase	17..509	CDD:304951	221/506 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	354	1.000	Domainoid score	I209
eggNOG	1	0.900	-	-		E1_COG0469
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	410	1.000	Inparanoid score	I455
OMA	1	1.010	-	-		QHG53565
OrthoDB	1	1.010	-	-		D933620at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1077
orthoMCL	1	0.900	-	-		OOG6_100258
Panther	1	1.100	-	-	O	PTHR11817
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X374
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.840