Protein Alignment PyK and CG11249

DIOPT Version :9

• Sequence 1: NP_524448.3
• Gene: PyK / 42620
• FlyBaseID: FBgn0267385
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_649346.1
• Gene: CG11249 / 40409
• FlyBaseID: FBgn0037115
• Length: 642
• Species: Drosophila melanogaster
• Alignment Length: 563
• Identity: 108/563 - (19%)
• Similarity: 223/563 - (39%)
• Gaps: 103/563 - (18%)

  Fly    20 QNMAAGADTQL------EHMCRLQFDSPVPHVRLSGIVCTIGPASSS-------VEM-------- 63
            ||.::.::.:|      |..|.:.|:....|...........|..:.       ||:
  Fly    85 QNCSSASEEELDFEELSEDPCNISFEEDRWHGFFKDFQILTTPVGTDPNENRKCVELTSMTNCDL 149

  Fly    64 -LEKMMATGMNIARMNFSHGSHEYHAATVANVRQAVKNYSAKLGYEHPVAIALDTK-GPEIRTGL 126
             ::..:..|:....:|...|:...:.:.:..:|:|..:.|.:||:  ||..::..| .|  |...
  Fly   150 EIKHHLLGGVRCFMVNLFEGTQHDNQSLIVKLREAEISVSKELGF--PVTSSVMVKISP--RHQF 210

  Fly   127 IGG-------SGTAEIELKKGEKIKLTTNKEFLEKGSLEIVYVDYENIVNVVKPGNRVFVDDGLI 184
            .||       .|...:||.:|:|:.||.::::.::.:.:::||:...::..|.|.:.:.:.:. |
  Fly   211 TGGFSTQFRQEGKKCVELVQGQKVILTVDRQYSDRSNADVIYVNARFLIVDVHPLDFILIGED-I 274

  Fly   185 SLIVREVGKDSLTCEVENGGSLGSRKGVNLPGVPVDLPA------VSEKDKSDLLFGVEQEVDMI 243
            .|:||.:..|.|...|..||.|.:.       :||..||      :|.::..||.|..|..::::
  Fly   275 QLMVRSIHADHLKGCVARGGMLYAH-------MPVLFPARCRRFRISYEELEDLTFAREVGLNVV 332

  Fly   244 FASFIRNAAALTEIRKVLGE---KGKNI---KIISKIENQQGMHNLDEIIEAGDGIMVARGDLGI 302
            .:..:.....:..:...:..   .|..:   .::::::..:|  .|:..|:..||.:|...:
  Fly   333 VSHIVGTPKYVDNLEHAMSAMHCDGMRLYARVVLNEVQGCKG--ELNWAIKRYDGFLVELAE--- 392

  Fly   303 EIPAEKVFLAQKAMIARC-----NKAGKPVICATQMLESMVKKPRPTRAEISDVANAVLDGADCV 362
              ||....:......|.|     ..|.||:|...::|:....:..|.....:..
  Fly   393 --PATVPDIMHLCPDAECFMQLTYAAKKPIIFDPRLLDEQKLRVDPAHYYYTFY----------- 444

  Fly   363 MLSGETAKGEYPLECVLTMAKTCKEAEAALWHQNL----FNDL----VRGAGTIDASH----AAA 415
                      ||.:.|    .||.:.:..::.:.|    |..:    :......|.||    :.|
  Fly   445 ----------YPDKYV----TTCPQPKGTIYFRLLQSAIFEQISPTALANTPYCDRSHTGADSLA 495

  Fly   416 IAAVEAATKAKASAIVVITTSGKSAFQVSKYRPRCPIIAVTRFAQTARQAHLYRGLVPLIYKEPG 480
            .:.|.|:.:..|.|||||..:.:...::|.:||..||:.|:..........:|..:..|.::...
  Fly   496 RSVVTASIEVHAVAIVVIGVTTRMVQKISHFRPHAPILFVSHMRSAEDYVSIYHNVTMLPFRTKC 560

  Fly   481 LGDWLKDVDVRVQFGLQVGKKNGFIKTGDSVVVVTGWKQGSGF 523
            :....::|.::..:.|....|....|..|.|::|..::.|:.|
  Fly   561 IIAHRRNVFLKAIYALAYLVKRKIAKQNDQVILVYNYEDGTKF 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PyK	NP_524448.3	Pyruvate_Kinase	46..532	CDD:238178	101/531 (19%)
		pyruv_kin	46..529	CDD:273424	101/531 (19%)
CG11249	NP_649346.1	Pyruvate_Kinase	158..>332	CDD:304951	45/185 (24%)
		PK_C	492..594	CDD:280960	23/101 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0469
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810