Protein Alignment PyK and Pkm

DIOPT Version :10

• Sequence 1: NP_524448.3
• Gene: PyK / 42620
• FlyBaseID: FBgn0267385
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: XP_006243250.3
• Gene: Pkm / 25630
• RGDID: 3337
• Length: 635
• Species: Rattus norvegicus
• Alignment Length: 517
• Identity: 340/517 - (65%)
• Similarity: 410/517 - (79%)
• Gaps: 1/517 - (0%)

  Fly    17 EVPQNMAAGADTQLEHMCRLQFDSPVPHVRLSGIVCTIGPASSSVEMLEKMMATGMNIARMNFSH 81
            :..|..||.|||.|||||||..||.....|.:||:|||||||.|||||::|:.:|||:||:||||
  Rat   118 QTQQLHAAMADTFLEHMCRLDIDSAPITARNTGIICTIGPASRSVEMLKEMIKSGMNVARLNFSH 182

  Fly    82 GSHEYHAATVANVRQAVKNYSAKLGYEHPVAIALDTKGPEIRTGLIGGSGTAEIELKKGEKIKLT 146
            |:|||||.|:.|||.|.:::::......|||:||||||||||||||.||||||:|||||..:|:|
  Rat   183 GTHEYHAETIKNVRAATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKIT 247

  Fly   147 TNKEFLEKGSLEIVYVDYENIVNVVKPGNRVFVDDGLISLIVREVGKDSLTCEVENGGSLGSRKG 211
            .:..::||....|:::||:||..||:.|::::||||||||.|:|.|.|.|..||||||||||:||
  Rat   248 LDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKEKGADYLVTEVENGGSLGSKKG 312

  Fly   212 VNLPGVPVDLPAVSEKDKSDLLFGVEQEVDMIFASFIRNAAALTEIRKVLGEKGKNIKIISKIEN 276
            |||||..||||||||||..||.|||||:|||:||||||.||.:.|:|||||||||||||||||||
  Rat   313 VNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKVLGEKGKNIKIISKIEN 377

  Fly   277 QQGMHNLDEIIEAGDGIMVARGDLGIEIPAEKVFLAQKAMIARCNKAGKPVICATQMLESMVKKP 341
            .:|:...|||:||.||||||||||||||||||||||||.||.|||:|||||||||||||||:|||
  Rat   378 HEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKP 442

  Fly   342 RPTRAEISDVANAVLDGADCVMLSGETAKGEYPLECVLTMAKTCKEAEAALWHQNLFNDLVRGAG 406
            ||||||.|||||||||||||:|||||||||:||||.|.......:|||||::|..||.:|.|.|.
  Rat   443 RPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAP 507

  Fly   407 -TIDASHAAAIAAVEAATKAKASAIVVITTSGKSAFQVSKYRPRCPIIAVTRFAQTARQAHLYRG 470
             |.|.:.|||:.||||:.|..:.||:|:|.||:||.||::||||.|||||||..|||||||||||
  Rat   508 ITSDPTEAAAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRG 572

  Fly   471 LVPLIYKEPGLGDWLKDVDVRVQFGLQVGKKNGFIKTGDSVVVVTGWKQGSGFTNTIRIVTV 532
            :.|::.|:..|..|.:|||:||...:.|||..||.|.||.|:|:|||:.|||||||:|:|.|
  Rat   573 IFPVLCKDAVLDAWAEDVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPV 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PyK	NP_524448.3	Pyruvate_Kinase	46..532	CDD:238178	324/486 (67%)
Pkm	XP_006243250.3	None