Protein Alignment PyK and LOC1275938

DIOPT Version :10

• Sequence 1: NP_524448.3
• Gene: PyK / 42620
• FlyBaseID: FBgn0267385
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: XP_061506259.1
• Gene: LOC1275938 / 1275938
• VectorBaseID: AGAMI1_009609
• Length: 727
• Species: Anopheles gambiae
• Alignment Length: 533
• Identity: 403/533 - (75%)
• Similarity: 458/533 - (85%)
• Gaps: 7/533 - (1%)

  Fly     1 MVNVTIYDEAPQLKPNEVPQNMAAGADTQLEHMCRLQFDSPVPHVRLSGIVCTIGPASSSVEMLE 65
            ||.|:.||..|:.|      .|...|.:.|||:|.|..||..|.||||||:|||||||.|.||||
Mosquito   198 MVWVSDYDFDPKGK------KMNPEAVSHLEHICSLDIDSKTPFVRLSGIICTIGPASVSPEMLE 256

  Fly    66 KMMATGMNIARMNFSHGSHEYHAATVANVRQAVKNYSAKLGYEHPVAIALDTKGPEIRTGLIGGS 130
            |||||||||||:|||||||||||.|:.|:|:||.|||.|||...|:||||||||||||||||.||
Mosquito   257 KMMATGMNIARLNFSHGSHEYHANTIKNIREAVDNYSKKLGKPFPLAIALDTKGPEIRTGLIEGS 321

  Fly   131 GTAEIELKKGEKIKLTTNKEFLEKGSLEIVYVDYENIVNVVKPGNRVFVDDGLISLIVREVGKDS 195
            ||.|:||||||||:|||:||.||||:.:.:||||.|||.|||||:.||||||||||:|..:..|:
Mosquito   322 GTGEVELKKGEKIQLTTDKEHLEKGTKDKIYVDYVNIVKVVKPGDHVFVDDGLISLVVESISGDT 386

  Fly   196 LTCEVENGGSLGSRKGVNLPGVPVDLPAVSEKDKSDLLFGVEQEVDMIFASFIRNAAALTEIRKV 260
            |||.|||||.|||||||||||||||||||||||||||.|||||.||:||||||||||||.|||.:
Mosquito   387 LTCTVENGGMLGSRKGVNLPGVPVDLPAVSEKDKSDLAFGVEQGVDVIFASFIRNAAALKEIRTI 451

  Fly   261 LGEKGKNIKIISKIENQQGMHNLDEIIEAGDGIMVARGDLGIEIPAEKVFLAQKAMIARCNKAGK 325
            ||||||:|||||||||||||.|||:||||.||||||||||||||||||||||||:||||||:|||
Mosquito   452 LGEKGKHIKIISKIENQQGMQNLDKIIEATDGIMVARGDLGIEIPAEKVFLAQKSMIARCNRAGK 516

  Fly   326 PVICATQMLESMVKKPRPTRAEISDVANAVLDGADCVMLSGETAKGEYPLECVLTMAKTCKEAEA 390
            ||||||||||||:||||||||||||||||::||||||||||||||||||||||||||||||||||
Mosquito   517 PVICATQMLESMIKKPRPTRAEISDVANAIIDGADCVMLSGETAKGEYPLECVLTMAKTCKEAEA 581

  Fly   391 ALWHQNLFNDLVRGAGT-IDASHAAAIAAVEAATKAKASAIVVITTSGKSAFQVSKYRPRCPIIA 454
            ||||:|||.|||....| :|.:.:.|||..||:.|::|:||:||||||:||..:|||||||||||
Mosquito   582 ALWHRNLFKDLVDTTPTPLDTAASIAIAGAEASIKSRAAAIIVITTSGRSAHLISKYRPRCPIIA 646

  Fly   455 VTRFAQTARQAHLYRGLVPLIYKEPGLGDWLKDVDVRVQFGLQVGKKNGFIKTGDSVVVVTGWKQ 519
            ||||||||||.|||||::|:||::|.:.|||||||.|||:|::.||:.||:|.|:.:||||||||
Mosquito   647 VTRFAQTARQCHLYRGILPVIYEQPAMEDWLKDVDARVQYGIEFGKERGFLKPGNPIVVVTGWKQ 711

  Fly   520 GSGFTNTIRIVTV 532
            |||||||||::.|
Mosquito   712 GSGFTNTIRVMYV 724

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PyK	NP_524448.3	Pyruvate_Kinase	46..532	CDD:238178	384/486 (79%)
LOC1275938	XP_061506259.1	None