DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5382 and zfpl1

DIOPT Version :9

Sequence 1:	NP_732721.1	Gene:	CG5382 / 42618	FlyBaseID:	FBgn0038950	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_001072211.1	Gene:	zfpl1 / 779657	XenbaseID:	XB-GENE-991966	Length:	320	Species:	Xenopus tropicalis

Alignment Length:	327	Identity:	132/327 - (40%)
Similarity:	167/327 - (51%)	Gaps:	50/327 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGLCKCPKRLVTNQFCFEHRVNVCEHCMVQSHPKCIVQSYLQWLRDSDYISNCTLCGTTLEQGDC 65
            |||||||||.|||.|||||||||||||:|.:|.|||||||||||:||||..||.||.|.|...:.
Frog     1 MGLCKCPKRKVTNLFCFEHRVNVCEHCLVANHAKCIVQSYLQWLQDSDYNPNCRLCNTLLSSKET 65

  Fly    66 VRLVCYHVFHWDCLNARQAALPANTAPRGHQCPACSVEIFPNANLVSPVADALKSFLSQVNWGRN 130
            .|||||.:|||.|||.....||.||||.|::||:|...:||.:|||||||..|:..||.|||.|.
Frog    66 ARLVCYDLFHWSCLNDLATQLPPNTAPAGYRCPSCQGPVFPPSNLVSPVAATLREKLSTVNWARA 130

  Fly   131 GLGLALLSEEQ---------------------SSSLKAIKPKVASQA-----AVSNMTKVHHIHS 169
            ||||.|:...:                     ||...:..|:..||.     :|......|.::.
Frog   131 GLGLPLIEVAEPVDDTMSHDETDYRDWSVVNSSSDNLSETPETTSQTGYAYNSVPTSVAQHSLNV 195

  Fly   170 GGERERTKPNGHDAVSPHSVLLMDAFNPPSAGDYASSRRPLLPRQSPIGGTDR----DDNKYQRR 230
            ...::            |:|.:.|..:.....:..||.|.:...:....|.|.    ||:||:||
Frog   196 NMSQD------------HAVTIRDTGSDSLTINAGSSPRKVYDTRETARGQDAVIDFDDDKYRRR 248

  Fly   231 TPAELFSRWTRRFYAPSSRPPWRRTWFLV--TAGILAFVLFVYLMAWLGRGGSDAVDEGWNNPNP 293
            ......:|..|......|||......|||  ..|:|.|:..:.||:.|||..:|      |:||.
Frog   249 PTLSWLARILRNRSGSKSRPASSMQRFLVILIIGVLGFLTLILLMSKLGRASAD------NDPNL 307

  Fly   294 QP 295
            .|
Frog   308 DP 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5382	NP_732721.1	zf-RING_2	52..100	CDD:290367	26/47 (55%)
CG5382	NP_732721.1	TctB	<235..>277	CDD:284693	13/43 (30%)
zfpl1	NP_001072211.1	mRING-H2-C3DHC3_ZFPL1	50..104	CDD:319401	27/53 (51%)
		modified RING-H2 finger (C3DHC3-type)	53..100	CDD:319401	25/46 (54%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	161..180		5/18 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	224	1.000	Domainoid score	I2503
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4935
Inparanoid	1	1.050	224	1.000	Inparanoid score	I3422
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489858at33208
OrthoFinder	1	1.000	-	-		FOG0006162
OrthoInspector	1	1.000	-	-		oto104264
Panther	1	1.100	-	-	LDO	PTHR12981
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2961
SonicParanoid	1	1.000	-	-		X4450
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.100