DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PSR and psr-1

DIOPT Version :9

Sequence 1:	NP_001262832.1	Gene:	PSR / 42616	FlyBaseID:	FBgn0038948	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_001294382.1	Gene:	psr-1 / 177229	WormBaseID:	WBGene00004205	Length:	416	Species:	Caenorhabditis elegans

Alignment Length:	388	Identity:	209/388 - (53%)
Similarity:	265/388 - (68%)	Gaps:	18/388 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 EEFKLPKRSRKRTREVKRKARPELDGENAWSAMRYCEKFE-PFWDFTDNLERIEESQVPESEFIE 66
            :.:.|| |:.||....|.|||||| .:..|..:.|.|.|. |  .|.|:::|::.:.:...||..
Worm    22 DRYSLP-RTYKRVSHAKDKARPEL-RKFGWETLGYSESFNLP--PFRDSIQRVDGNNLTVEEFRR 82

  Fly    67 RFERPYKPVVIRGCTDGWLALEKWTLARLAKKYRNQKFKCGEDNEGYSVKMKMKYYVEYMQSTRD 131
            .||||..||:|.|.||.|.|.:|||:.||:||||||.||||||:.|.||:||||||.:||.:.:|
Worm    83 DFERPRIPVIITGLTDNWAAKDKWTVERLSKKYRNQNFKCGEDDNGNSVRMKMKYYHDYMLNNKD 147

  Fly   132 DSPLYIFDSSFGEHHRRRKLLDDYVVPKYFRDDLFQYCGENRRPPYRWFVMGPARSGTGIHIDPL 196
            |||||||||||.|..:.:||.:||.|||:|.||||.|..:.:|||:||||||||||||.||||||
Worm   148 DSPLYIFDSSFAERRKTKKLSEDYSVPKFFEDDLFHYADDKKRPPHRWFVMGPARSGTAIHIDPL 212

  Fly   197 GTSAWNTLIRGHKRWCLFPTQTPKELLKVTSAMGGKQRDEAITWFSTIYPRTQLPSWPEQYRPIE 261
            ||||||:|::|||||.|.|...|::|:|..:...||..||.||||.|:|.|.:.||||::|.|||
Worm   213 GTSAWNSLLQGHKRWVLIPPIAPRDLVKPMAHEKGKHPDEGITWFQTVYKRVRSPSWPKEYAPIE 277

  Fly   262 VLQGAGETVFVPGGWWHVVLNMDDTIAITQNFSSQTNFPCVWHKTVRGRPKLSRKWLRVLRDQRP 326
            ..||.|||:|||.||||||:|.:.|||:|.|:.|..|...||.|||:||||||:.|::.|.:|||
Worm   278 CRQGPGETMFVPSGWWHVVINEEYTIAVTHNYCSVENLHLVWPKTVKGRPKLSKHWVKRLTEQRP 342

  Fly   327 ELAQI---ADSINLNESTGFASDSSSNSSSSSSSSSSSSEEEESDDGG------DSNTDSGQE 380
            ||.:|   |..|.|.:    .::|||:||||||||..||:|.:.||.|      ..|.|...|
Worm   343 ELLEIIKSASEIPLYD----MNESSSDSSSSSSSSDDSSDESDCDDSGRCGGRKRKNDDRSNE 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PSR	NP_001262832.1	JmjC	179..293	CDD:202224	72/113 (64%)
psr-1	NP_001294382.1	DUF1007	<126..209	CDD:382562	53/82 (65%)
psr-1	NP_001294382.1	JmjC	195..308	CDD:334913	72/112 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161238
Domainoid	1	1.000	188	1.000	Domainoid score	I1961
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9046
Inparanoid	1	1.050	421	1.000	Inparanoid score	I1003
Isobase	1	0.950	-	0	Normalized mean entropy	S2343
OMA	1	1.010	-	-		QHG58658
OrthoDB	1	1.010	-	-		D369628at33208
OrthoFinder	1	1.000	-	-		FOG0005710
OrthoInspector	1	1.000	-	-		oto18508
orthoMCL	1	0.900	-	-		OOG6_101565
Panther	1	1.100	-	-	LDO	PTHR12480
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3963
SonicParanoid	1	1.000	-	-		X4108
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.890