Protein Alignment Sar1 and Sar1b

DIOPT Version :10

• Sequence 1: NP_732717.1
• Gene: Sar1 / 42615
• FlyBaseID: FBgn0038947
• Length: 193
• Species: Drosophila melanogaster
• Sequence 2: NP_079811.1
• Gene: Sar1b / 66397
• MGIID: 1913647
• Length: 198
• Species: Mus musculus
• Alignment Length: 196
• Identity: 141/196 - (71%)
• Similarity: 163/196 - (83%)
• Gaps: 4/196 - (2%)

  Fly     2 FIWDW----FTGVLGYLGLWKKSGKLLFLGLDNAGKTTLLHMLKDDKLAQHVPTLHPTSEELSIG 62
            ||:||    |:.||.:|||:||||||:|||||||||||||||||||:|.|||||||||||||:|.
Mouse     3 FIFDWIYSGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIA 67

  Fly    63 NMRFTTFDLGGHTQARRVWKDYFPAVDAIVFLIDAWDRGRFQESKNELDSLLTDEALSNCPVLIL 127
            .|.|||||||||.|||||||:|.||::.||||:|..|..|..|||.|||||:|||.::|.|:|||
Mouse    68 GMTFTTFDLGGHVQARRVWKNYLPAINGIVFLVDCADHERLLESKEELDSLMTDETIANVPILIL 132

  Fly   128 GNKIDKPGAASEDELRNVFGLYQLTTGKGKVARADLPGRPLELFMCSVLKRQGYGEGFRWLAQYI 192
            |||||:|.|.||:.||.:||||..|||||.|:..:|..||||:|||||||||||||||||:||||
Mouse   133 GNKIDRPEAISEERLREMFGLYGQTTGKGSVSLKELNARPLEVFMCSVLKRQGYGEGFRWMAQYI 197

  Fly   193 D 193
            |
Mouse   198 D 198

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sar1	NP_732717.1	Sar1	2..192	CDD:206645	138/193 (72%)
Sar1b	NP_079811.1	Sar1	3..197	CDD:206645	138/193 (72%)
		STAR, SAR1-N-terminal activation recruitment. Required for the activation by PREB and subsequent recruitment to ER membrane. /evidence=ECO:0000250|UniProtKB:Q9QVY3	3..5		1/1 (100%)
		Mediates recruitment to ER membranes. /evidence=ECO:0000250|UniProtKB:Q9QVY3	15..19		2/3 (67%)