DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sar1 and SAR1B

DIOPT Version :9

Sequence 1:	NP_732717.1	Gene:	Sar1 / 42615	FlyBaseID:	FBgn0038947	Length:	193	Species:	Drosophila melanogaster
Sequence 2:	NP_001028675.1	Gene:	SAR1B / 51128	HGNCID:	10535	Length:	198	Species:	Homo sapiens

Alignment Length:	196	Identity:	139/196 - (70%)
Similarity:	163/196 - (83%)	Gaps:	4/196 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 FIWDW----FTGVLGYLGLWKKSGKLLFLGLDNAGKTTLLHMLKDDKLAQHVPTLHPTSEELSIG 62
            ||:||    |:.||.:|||:||:|||:|||||||||||||||||||:|.|||||||||||||:|.
Human     3 FIFDWIYSGFSSVLQFLGLYKKTGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIA 67

  Fly    63 NMRFTTFDLGGHTQARRVWKDYFPAVDAIVFLIDAWDRGRFQESKNELDSLLTDEALSNCPVLIL 127
            .|.|||||||||.|||||||:|.||::.||||:|..|..|..|||.|||||:|||.::|.|:|||
Human    68 GMTFTTFDLGGHVQARRVWKNYLPAINGIVFLVDCADHERLLESKEELDSLMTDETIANVPILIL 132

  Fly   128 GNKIDKPGAASEDELRNVFGLYQLTTGKGKVARADLPGRPLELFMCSVLKRQGYGEGFRWLAQYI 192
            |||||:|.|.||:.||.:||||..|||||.::..:|..||||:|||||||||||||||||:||||
Human   133 GNKIDRPEAISEERLREMFGLYGQTTGKGSISLKELNARPLEVFMCSVLKRQGYGEGFRWMAQYI 197

  Fly   193 D 193
            |
Human   198 D 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sar1	NP_732717.1	Sar1	2..192	CDD:206645	136/193 (70%)
SAR1B	NP_001028675.1	Sar1	3..197	CDD:206645	136/193 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	282	1.000	Domainoid score	I1665
eggNOG	1	0.900	-	-		E1_KOG0077
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H90905
Inparanoid	1	1.050	292	1.000	Inparanoid score	I2790
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54210
OrthoDB	1	1.010	-	-		D1168548at2759
OrthoFinder	1	1.000	-	-		FOG0001618
OrthoInspector	1	1.000	-	-		otm40846
orthoMCL	1	0.900	-	-		OOG6_101164
Panther	1	1.100	-	-	LDO	PTHR45684
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1287
SonicParanoid	1	1.000	-	-		X1187
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.870