Protein Alignment Sar1 and ARF1

DIOPT Version :10

• Sequence 1: NP_732717.1
• Gene: Sar1 / 42615
• FlyBaseID: FBgn0038947
• Length: 193
• Species: Drosophila melanogaster
• Sequence 2: NP_001649.1
• Gene: ARF1 / 375
• HGNCID: 652
• Length: 181
• Species: Homo sapiens
• Alignment Length: 188
• Identity: 57/188 - (30%)
• Similarity: 96/188 - (51%)
• Gaps: 21/188 - (11%)

  Fly     7 FTGVLGYLGLWKKSGKLLFLGLDNAGKTTLLHMLKDDKLAQHVPTLHPTSEELSIGNMRFTTFDL 71
            |.|:.|     ||..::|.:|||.|||||:|:.||..::...:||:....|.:...|:.||.:|:
Human     9 FKGLFG-----KKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDV 68

  Fly    72 GGHTQARRVWKDYFPAVDAIVFLIDAWDRGRFQESKNELDSLLTDEALSNCPVLILGNKIDKPGA 136
            ||..:.|.:|:.||.....::|::|:.||.|..|::.||..:|.::.|.:..:|:..||.|.|.|
Human    69 GGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNA 133

  Fly   137 ASEDELRNVFGLYQLTTGKGKVARADLPGRPLELFMCSVLKRQGYG--EGFRWLAQYI 192
            .:..|:.:..||:.|              |....::.:.....|.|  ||..||:..:
Human   134 MNAAEITDKLGLHSL--------------RHRNWYIQATCATSGDGLYEGLDWLSNQL 177

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sar1	NP_732717.1	Sar1	2..192	CDD:206645	57/186 (31%)
ARF1	NP_001649.1	Important for the stable binding to the membranes. /evidence=ECO:0000250|UniProtKB:P84080	3..16		3/11 (27%)
		ARF	5..179	CDD:128474	57/188 (30%)