Protein Alignment rdhB and DHRS11

DIOPT Version :9

• Sequence 1: NP_001262831.1
• Gene: rdhB / 42614
• FlyBaseID: FBgn0038946
• Length: 248
• Species: Drosophila melanogaster
• Sequence 2: NP_077284.2
• Gene: DHRS11 / 79154
• HGNCID: 28639
• Length: 260
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 97/258 - (37%)
• Similarity: 147/258 - (56%)
• Gaps: 25/258 - (9%)

  Fly     7 WRNKVAVVTGASVGIGATTAIELANAGMVVVGLARRVELIEALRDQVTGV---GKIFARQCDLND 68
            ||:::|:|||||.||||..|..|...|:.|||.||.|..||.|..:....   |.:...:|||::
Human     9 WRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCDLSN 73

  Fly    69 EEQLASAFNWIREKFQAIHVLICNAGILKANFLSESPTKDIKELFDTNVVATASCLREALKHMAA 133
            ||.:.|.|:.||.:...:.:.|.|||:.:.:.|....|...|::|:.||:|.:.|.|||.:.|..
Human    74 EEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKE 138

  Fly   134 VKV-RGHIVVMNSVLGHRIPEVPVPLFSVYPATKHAITALCQTVRQEIHFLKLNIKLTSICPGMV 197
            ..| .|||:.:||:.|||:  :|:.:...|.|||:|:|||.:.:|||:...:.:|:.|.|.||:|
Human   139 RNVDDGHIININSMSGHRV--LPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVV 201

  Fly   198 DTDF------------LSVYSQAVAELPKLQARDVAKAVLYALNTPDGVQVEDIILQQMRKVD 248
            :|.|            .:.|.|    :..|:..|||:||:|.|:||..:|:.||   |||..:
Human   202 ETQFAFKLHDKDPEKAAATYEQ----MKCLKPEDVAEAVIYVLSTPAHIQIGDI---QMRPTE 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdhB	NP_001262831.1	Mgc4172-like_SDR_c	4..244	CDD:187601	94/252 (37%)
		YdfG	9..241	CDD:226674	92/247 (37%)
DHRS11	NP_077284.2	Mgc4172-like_SDR_c	6..256	CDD:187601	97/255 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1205
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2090
OMA	1	1.010	-	-		QHG45743
OrthoDB	1	1.010	-	-		D1190834at2759
OrthoFinder	1	1.000	-	-		FOG0000588
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43115
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.880