Protein Alignment rdhB and Rdh8

DIOPT Version :10

• Sequence 1: NP_651024.1
• Gene: rdhB / 42614
• FlyBaseID: FBgn0038946
• Length: 248
• Species: Drosophila melanogaster
• Sequence 2: NP_001162065.1
• Gene: Rdh8 / 690953
• RGDID: 1589829
• Length: 312
• Species: Rattus norvegicus
• Alignment Length: 222
• Identity: 55/222 - (24%)
• Similarity: 104/222 - (46%)
• Gaps: 37/222 - (16%)

  Fly    13 VVTGASVGIGATTAIELANAGMVVVGLARRVELIEALRDQVTGVGK---------------IFAR 62
            :::|.|.|||...|::||:      ...:|.:::..:||    :||               :...
  Rat     9 LISGCSSGIGLELAVQLAH------DPRQRYQVVATMRD----LGKKEPLEAAAGEALGKTLSVA 63

  Fly    63 QCDLNDEEQLASAFNWIREKFQAIHVLICNAGILKANFLSESPTKDIKELFDTNVVATASCLREA 127
            |.|:..:|.:.:..:.| |..| :.:|:.|||:.....|.:.....::.:|:||.......::..
  Rat    64 QLDVCSDESVTNCLSHI-EGGQ-VDILVNNAGVGLVGPLEDLSLATMQNVFNTNFFGAVRLVKAV 126

  Fly   128 LKHMAAVKVRGHIVVMNSVLGHRIPEVPVPLFSVYPATKHAITALCQTVRQEIHFLKLNIKLTSI 192
            |..|.. :.:|||||::||:|.:    .|....||.|:|.|:....:::  .|...:.||.::.:
  Rat   127 LPGMKR-RRQGHIVVVSSVMGLQ----GVMFNDVYAASKFALEGFFESL--AIQLRQFNIFISMV 184

  Fly   193 CPGMVDTDFLSVYSQAVAELPKLQARD 219
            .||.|.|||   ..:.:|::.|.:..|
  Rat   185 EPGPVITDF---EGKLLAQVSKTEFPD 208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdhB	NP_651024.1	Mgc4172-like_SDR_c	4..244	CDD:187601	55/222 (25%)
Rdh8	NP_001162065.1	Rossmann-fold NAD(P)(+)-binding proteins	8..262	CDD:473865	55/222 (25%)