Protein Alignment rdhB and RDH8

DIOPT Version :9

• Sequence 1: NP_001262831.1
• Gene: rdhB / 42614
• FlyBaseID: FBgn0038946
• Length: 248
• Species: Drosophila melanogaster
• Sequence 2: NP_056540.3
• Gene: RDH8 / 50700
• HGNCID: 14423
• Length: 311
• Species: Homo sapiens
• Alignment Length: 221
• Identity: 56/221 - (25%)
• Similarity: 103/221 - (46%)
• Gaps: 37/221 - (16%)

  Fly    10 KVAVVTGASVGIGATTAIELANAGMVVVGLARRVELIEALRDQVTGVGK---------------I 59
            :..:::|.|.|||...|::||:      ...:|.:::..:||    :||               :
Human     6 RTVLISGCSSGIGLELAVQLAH------DPKKRYQVVATMRD----LGKKETLEAAAGEALGQTL 60

  Fly    60 FARQCDLNDEEQLASAFNWIREKFQAIHVLICNAGILKANFLSESPTKDIKELFDTNVVATASCL 124
            ...|.|:..:|.:|...:.|:.:   :.||:.|||:.....|.......::.:||||.......:
Human    61 TVAQLDVCSDESVAQCLSCIQGE---VDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVRLV 122

  Fly   125 REALKHMAAVKVRGHIVVMNSVLGHRIPEVPVPLFSVYPATKHAITALCQTVRQEIHFLKLNIKL 189
            :..|..|.. :.:|||||::||:|.:    .|....||.|:|.|:....:::  .|..|:.||.:
Human   123 KAVLPGMKR-RRQGHIVVISSVMGLQ----GVIFNDVYAASKFALEGFFESL--AIQLLQFNIFI 180

  Fly   190 TSICPGMVDTDFLS--VYSQAVAELP 213
            :.:.||.|.|:|..  :...::||.|
Human   181 SLVEPGPVVTEFEGKLLAQVSMAEFP 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdhB	NP_001262831.1	Mgc4172-like_SDR_c	4..244	CDD:187601	56/221 (25%)
		YdfG	9..241	CDD:226674	56/221 (25%)
RDH8	NP_056540.3	type1_17beta-HSD-like_SDR_c	6..262	CDD:187666	56/221 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1205
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810