DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdhB and Dhrs11

DIOPT Version :9

Sequence 1:	NP_001262831.1	Gene:	rdhB / 42614	FlyBaseID:	FBgn0038946	Length:	248	Species:	Drosophila melanogaster
Sequence 2:	XP_038942294.1	Gene:	Dhrs11 / 360583	RGDID:	1307935	Length:	299	Species:	Rattus norvegicus

Alignment Length:	246	Identity:	91/246 - (36%)
Similarity:	134/246 - (54%)	Gaps:	32/246 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 WRNKVAVVTGASVGIGATTAIELANAGMVVVGLARRVELIEALRDQVTGV---GKIFARQCDLND 68
            ||:::|:|||||.||||..|..|...|:.|||.||.|..||.|..:....   |.:...:|||::
  Rat    79 WRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCDLSN 143

  Fly    69 EEQLASAFNWIREKFQAIHVLICNAGILKANFLSESPTKDIKELFDTNVVATASCLREALKHMAA 133
            ||.:.|.|:.:|.:...:.:.|.|||:.:.:.|....|...|::|:.||:|.:.|.|||.:.|..
  Rat   144 EEDILSMFSAVRSQHSGVDICINNAGMARPDSLLSGSTSGWKDMFNVNVLALSICTREAYQSMKE 208

  Fly   134 VKV-RGHIVVMNSVLGHRIPEVPVPLFSVYPATKHAITALCQTVRQEIHFLKLNIKLTSICPGMV 197
            ..| .|||:.:||:.|||:|  |..:...|.|||:|:|||.:.:|||:...:.:|:.|.:.|
  Rat   209 RNVDDGHIININSMCGHRVP--PQSVIHFYSATKYAVTALTEGLRQELLEAQTHIRATCLRP--- 268

  Fly   198 DTDFLSVYSQAVAELPKLQARDVAKAVLYALNTPDGVQVEDIILQQMRKVD 248
                                .|||:||:|.|:||..|||.||   |||..:
  Rat   269 --------------------EDVAEAVIYVLSTPPHVQVGDI---QMRPTE 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdhB	NP_001262831.1	Mgc4172-like_SDR_c	4..244	CDD:187601	88/240 (37%)
rdhB	NP_001262831.1	YdfG	9..241	CDD:226674	86/235 (37%)
Dhrs11	XP_038942294.1	Mgc4172-like_SDR_c	76..295	CDD:187601	91/243 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1205
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45743
OrthoDB	1	1.010	-	-		D1190834at2759
OrthoFinder	1	1.000	-	-		FOG0000588
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43115
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.890