Protein Alignment rdhB and Dhrs7b

DIOPT Version :10

• Sequence 1: NP_651024.1
• Gene: rdhB / 42614
• FlyBaseID: FBgn0038946
• Length: 248
• Species: Drosophila melanogaster
• Sequence 2: NP_001008507.1
• Gene: Dhrs7b / 287380
• RGDID: 1311243
• Length: 325
• Species: Rattus norvegicus
• Alignment Length: 254
• Identity: 76/254 - (29%)
• Similarity: 120/254 - (47%)
• Gaps: 31/254 - (12%)

  Fly     6 YWRNKVAVVTGASVGIGATTAIELANAGMVVVGLARRVELIE----ALRDQVTGVGKIFARQC-- 64
            |.||.|.|||||:.|:|...|.....||..||...|.|:.:|    .|.|..:..|:.. :.|
  Rat    49 YLRNAVVVVTGATSGLGKECARVFHAAGAKVVLCGRNVKALEEFTRELADSSSSQGQTH-QPCVV 112

  Fly    65 --DLNDEEQLASAFNWIREKFQAIHVLICNAGILKANFLSESPTKDIKELFDTNVVATASCLREA 127
              ||.|...:|.|...|.:.|..:.:||.||||.....:|::.....:::.:.|.....:..:..
  Rat   113 TFDLADPGAIAPAAAEILQCFGYVDILINNAGISYRGAISDTIVDVDRKVMEINYFGPVALTKAL 177

  Fly   128 LKHMAAVKVRGHIVVMNSVLGHRIPEVPVPLFSVYPATKHAITALCQTVRQEIHFLKLNIKLTSI 192
            |..|...| |||||.::|:.|    ::.:|..|.|.|:|||..|....:|.|:.  ..:|::|.|
  Rat   178 LPSMVERK-RGHIVAISSIQG----KISIPFRSAYAASKHATQAFFDCLRAEMK--DSDIEVTVI 235

  Fly   193 CPGMVDTDFLSVYS-----QAVAELPKLQAR-----DVAKAVLYALNTPDGVQVEDIIL 241
            .||.:.|: |||.:     .....|.|..|:     :||:.:..|:    |.:.:|::|
  Rat   236 SPGYIHTN-LSVNAVTADGSRYGALDKNTAQGRSAVEVAQDIFDAV----GKKKKDVLL 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdhB	NP_651024.1	Mgc4172-like_SDR_c	4..244	CDD:187601	76/254 (30%)
Dhrs7b	NP_001008507.1	11beta-HSD1_like_SDR_c	50..311	CDD:187593	75/253 (30%)