Protein Alignment rdhB and Cbr4

DIOPT Version :10

• Sequence 1: NP_651024.1
• Gene: rdhB / 42614
• FlyBaseID: FBgn0038946
• Length: 248
• Species: Drosophila melanogaster
• Sequence 2: NP_663570.2
• Gene: Cbr4 / 234309
• MGIID: 2384567
• Length: 236
• Species: Mus musculus
• Alignment Length: 239
• Identity: 55/239 - (23%)
• Similarity: 110/239 - (46%)
• Gaps: 37/239 - (15%)

  Fly     9 NKVAVVTGASVGIGATTAIELANAGMVVVGLARRVELIEALRDQVTGVGKIFARQCDLNDEEQLA 73
            :||..|.|.|.|||...|..:|..|..:..::|.:|:.:....::.  |...|.:||:..|:.:.
Mouse     2 DKVCAVFGGSRGIGRAVAQLMAQKGYRLAIVSRNLEVAKVTAGELG--GNHLAFRCDVAKEQDVQ 64

  Fly    74 SAFNWIREKFQAIHVLICNAGILKANFLSESPTKDIKELFDTNVVATASCLREALKHMAAVKVRG 138
            |.|..:.:....::.|:..|||.:.:.|..:.|:|:.....||::.:....:.|:|.|  ::..|
Mouse    65 STFQEMEKHLGPVNFLVNAAGINRDSLLVRTKTEDMISQLHTNLLGSMLTCKAAMKTM--IQQGG 127

  Fly   139 HIVVMNSVLGHR--IPEVPVPLFSVYPATKHAITALCQTVRQEIHFLKLNIKLTSICPGMVDTDF 201
            .||.:.|::|.:  :.:      |.|.|||..:....:::.:|:  .:..|::..:.||.:.||.
Mouse   128 SIVNVGSIIGLKGNVGQ------SAYSATKGGLVGFSRSLAKEV--ARKKIRVNVVAPGFIRTDM 184

  Fly   202 --------------LSVYSQAVAELPKLQARDVAKAVLYALNTP 231
                          |..:.:.:         :||.||::.|.:|
Mouse   185 TRHLKEEHFKKNIPLGRFGETL---------EVAHAVVFLLESP 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdhB	NP_651024.1	Mgc4172-like_SDR_c	4..244	CDD:187601	55/239 (23%)
Cbr4	NP_663570.2	Rossmann-fold NAD(P)(+)-binding proteins	3..232	CDD:473865	55/238 (23%)