Protein Alignment rdhB and Dhrs7l

DIOPT Version :10

• Sequence 1: NP_651024.1
• Gene: rdhB / 42614
• FlyBaseID: FBgn0038946
• Length: 248
• Species: Drosophila melanogaster
• Sequence 2: NP_001423196.1
• Gene: Dhrs7l / 209183
• MGIID: 3644906
• Length: 335
• Species: Mus musculus
• Alignment Length: 384
• Identity: 82/384 - (21%)
• Similarity: 129/384 - (33%)
• Gaps: 106/384 - (27%)

  Fly     2 LGSASDTKK----LLSERDLL-RVMEQDRHSIAPEVHP---DEQLPFDEHDFVAHFQRVSISGED 58
            |..|.|.|.    |...|||. ||....|.:...:|.|   :.|.|......|. |||..:..|.
Mouse   943 LSKAEDEKHRQLLLQPNRDLFSRVCAPRRKADPAQVEPTVSNLQSPHIRPSLVT-FQRTKLGSES 1006

  Fly    59 TSGVPLDDLERASTLLVKALELREKYMRNSHQAFPQTTARFLKSTHSSTITH----QERKSIADH 119
            ...|...||...|.       .|:..::...:|  ||.....|.....:..:    .||:.:|..
Mouse  1007 PQIVKKGDLPSRSA-------ARQTQIQTDVRA--QTPGASAKEIQLQSELYGKLVSERQKLASI 1062

  Fly   120 PVNPP-----------QSTQSPWVVEIPEDLNYSIRPVHGVFEVFPAVESTEPLPYQYTRLPDFV 173
            ...||           .|...|..:.       |::.|.||.|...|:         .|.|.|.:
Mouse  1063 RDIPPALLATNKILLDMSKLRPCTMS-------SLKQVDGVSEAKAAM---------LTPLIDII 1111

  Fly   174 ------QDMQMMCSMIADGPLKSFCYRR-------------LSYLYSKFQL-HVLLNELRELASQ 218
                  ..:|:..|..:...:::...|.             :|..||.||: |   ..||:::..
Mouse  1112 AKFCQTHGLQVDVSSNSASSVQTHSSRESVVGSVAQCLPDSISITYSLFQIEH---KSLRQVSDA 1173

  Fly   219 KAVPHRDFYNIRKVDTHIHAASCM------NQKHLLRFIKKTL-KNSAD----EVVTVTKGTPMT 272
            :::|      |..|::|:..|..|      ::..|...|..|: ||:|.    :...|....|..
Mouse  1174 RSLP------IAVVESHLLQAQKMGCAVDTDRAGLSTSIMNTIRKNTAGSDLCDFKAVRSRVPED 1232

  Fly   273 LAQVFQSMNLTTYDLTVDMLDVHADRNTFHR------FDKFNA----KYNPIGESRLRE 321
            ::...  :.|..|:|..:     |...|.|.      .||.:.    ...|:.|.|.:|
Mouse  1233 ISNFL--LRLAIYELQKE-----ASSTTRHEISWIEPLDKSSTATRLAEKPVCEERQQE 1284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdhB	NP_651024.1	Mgc4172-like_SDR_c	4..244	CDD:187601	61/288 (21%)
Dhrs7l	NP_001423196.1	11beta-HSD1_like_SDR_c	48..305	CDD:187593