Protein Alignment rdhB and DHRS7C

DIOPT Version :10

• Sequence 1: NP_651024.1
• Gene: rdhB / 42614
• FlyBaseID: FBgn0038946
• Length: 248
• Species: Drosophila melanogaster
• Sequence 2: NP_001207422.1
• Gene: DHRS7C / 201140
• HGNCID: 32423
• Length: 312
• Species: Homo sapiens
• Alignment Length: 202
• Identity: 45/202 - (22%)
• Similarity: 88/202 - (43%)
• Gaps: 24/202 - (11%)

  Fly     8 RNKVAVVTGASVGIGATTAIELANAGMVVVGLARRVELIEALRDQVTGVG----KIFARQ---CD 65
            :|||.|:|.|..|:|...|......|..:|...:..|.:|.|.|.:..|.    :.|..:   .|
Human    36 QNKVVVITDAISGLGKECARVFHTGGARLVLCGKNWERLENLYDALISVADPSKQTFTPKLVLLD 100

  Fly    66 LNDEEQLASAFNWIREKFQAIHVLICNAGILKANFLSESPTKDI-----KELFDTNVVATASCLR 125
            |:|...:......:.:.:..:.:||.||.:     ..:.|...|     |::.|.|.....:..:
Human   101 LSDISCVPDVAKEVLDCYGCVDILINNASV-----KVKGPAHKISLELDKKIMDANYFGPITLTK 160

  Fly   126 EALKHMAAVKVRGHIVVMNSVLGHRIPEVPVPLFSVYPATKHAITALCQTVRQEIHFLKLNIKLT 190
            ..|.:|.:.:. |.||::|::.|    :..:|..:.|.|:|||.......:|.|:.  :.::.::
Human   161 ALLPNMISRRT-GQIVLVNNIQG----KFGIPFRTTYAASKHAALGFFDCLRAEVE--EYDVVIS 218

  Fly   191 SICPGMV 197
            ::.|..:
Human   219 TVSPTFI 225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdhB	NP_651024.1	Mgc4172-like_SDR_c	4..244	CDD:187601	45/202 (22%)
DHRS7C	NP_001207422.1	11beta-HSD1_like_SDR_c	35..297	CDD:187593	45/202 (22%)