Protein Alignment rdhB and Hsd17b1

DIOPT Version :9

• Sequence 1: NP_001262831.1
• Gene: rdhB / 42614
• FlyBaseID: FBgn0038946
• Length: 248
• Species: Drosophila melanogaster
• Sequence 2: NP_034605.1
• Gene: Hsd17b1 / 15485
• MGIID: 105077
• Length: 344
• Species: Mus musculus
• Alignment Length: 259
• Identity: 67/259 - (25%)
• Similarity: 109/259 - (42%)
• Gaps: 54/259 - (20%)

  Fly    11 VAVVTGASVGIGATTAIELA---NAGMVVVGLARRVE----LIEALRDQVTGVGKIFARQCDLND 68
            |.::||.|.|||...|:.||   :....|....|.::    |:||.|.|....|.:...:.|:.|
Mouse     5 VVLITGCSSGIGMHLAVRLASDRSQSFKVYATLRDLKAQGPLLEAARTQGCPPGSLEILELDVRD 69

  Fly    69 EEQLASAFNWIREKFQAIHVLICNA-----GILKANFLSESPTKDIKELFDTNVVATASCLREAL 128
            .:.:|:|...:.|  ..:.||:|||     |.|:|:.|:.     :..:.|.||:.|...|:..|
Mouse    70 SKSVAAAQACVTE--GRVDVLVCNAGRGLFGPLEAHELNA-----VGAVLDVNVLGTIRMLQAFL 127

  Fly   129 KHMAAVKVRGHIVVMNSVLGHRIPEVPVPLFSVYPATKHAITALCQTVRQEIHFLKLNIKLTSIC 193
            ..|.. :..|.::|..||.|    .:.:|...||.|:|.|:..||:::...:....:::.|.. |
Mouse   128 PDMKR-RHSGRVLVTASVGG----LMGLPFHEVYCASKFALEGLCESLAILLPLFGVHVSLIE-C 186

  Fly   194 PGMVDTDF--------------------------LSVYSQAVAELPKLQARDVAKAVLYALNTP 231
             |.|.|.|                          |..|.||::|..  ...:|.:..|.|:..|
Mouse   187 -GAVHTAFYEKLVGGPGGALERADAQTRHLFAHYLRGYEQALSEAQ--DPEEVTELFLTAMRAP 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdhB	NP_001262831.1	Mgc4172-like_SDR_c	4..244	CDD:187601	67/259 (26%)
		YdfG	9..241	CDD:226674	67/259 (26%)
Hsd17b1	NP_034605.1	NADB_Rossmann	4..260	CDD:304358	67/259 (26%)
		adh_short	5..192	CDD:278532	56/200 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1205
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900