Protein Alignment rdhB and Hsd11b1

DIOPT Version :10

• Sequence 1: NP_651024.1
• Gene: rdhB / 42614
• FlyBaseID: FBgn0038946
• Length: 248
• Species: Drosophila melanogaster
• Sequence 2: XP_006497291.1
• Gene: Hsd11b1 / 15483
• MGIID: 103562
• Length: 304
• Species: Mus musculus
• Alignment Length: 217
• Identity: 53/217 - (24%)
• Similarity: 97/217 - (44%)
• Gaps: 52/217 - (23%)

  Fly     8 RNKVAVVTGASVGIGATTAIELANAGMVVVGLARRVELIEALRDQVTGVGKIFARQCDLNDEEQL 72
            :.|..:|||||.|||...|..|:..|..||..||..|          |:.|:.:|..:|.
Mouse    45 QGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEE----------GLQKVVSRCLELG----- 94

  Fly    73 ASAFNWI---REKFQAIHVLICNAG-------ILKANFLSESPTK-------DIKELFDTN---- 116
            |::.::|   .|........|..||       :|..|.::::...       .::.:.:.|
Mouse    95 AASAHYIAGTMEDMTFAEQFIVKAGKLMGGLDMLILNHITQTSLSLFHDDIHSVRRVMEVNFLSY 159

  Fly   117 -VVATAS--CLREALKHMAAVKVRGHIVVMNSVLGHRIPEVPVPLFSVYPATKHAITALCQTVRQ 178
             |::||:  .|:::         .|.|.|::|:.|    ::..|:.:.|.|:|.|:.....|:|.
Mouse   160 VVMSTAALPMLKQS---------NGSIAVISSLAG----KMTQPMIAPYSASKFALDGFFSTIRT 211

  Fly   179 EIHFLKLNIKLTSICPGMVDTD 200
            |::..|:|:.:|....|::||:
Mouse   212 ELYITKVNVSITLCVLGLIDTE 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdhB	NP_651024.1	Mgc4172-like_SDR_c	4..244	CDD:187601	53/217 (24%)
Hsd11b1	XP_006497291.1	11beta-HSD1_like_SDR_c	44..291	CDD:187593	53/217 (24%)