Protein Alignment CG34377 and Inppl1

DIOPT Version :10

• Sequence 1: NP_001262830.1
• Gene: CG34377 / 42608
• FlyBaseID: FBgn0263117
• Length: 453
• Species: Drosophila melanogaster
• Sequence 2: NP_034697.2
• Gene: Inppl1 / 16332
• MGIID: 1333787
• Length: 1257
• Species: Mus musculus
• Alignment Length: 160
• Identity: 42/160 - (26%)
• Similarity: 61/160 - (38%)
• Gaps: 42/160 - (26%)

  Fly    21 PLATGVGSSGVSGASGASGAS-GASTSTKPQRLNKVSFA-----------PLDLPFPSGATXYAN 73
            ||..|...:.......|||.. ..|.....:.|::|.:|           ||:|..|.|.:.|..
Mouse  1099 PLPPGTSPASTFLGEVASGDDRSCSVLQMAKTLSEVDYAPGPGRSALLPNPLELQPPRGPSDYGR 1163

  Fly    74 ANASTSMPHHNI---------------------------VCEWLRTIGLAHYGESFLENGYDELE 111
               ..|.|...|                           :..|||.|||..|.|..:.||:|:||
Mouse  1164 ---PLSFPPPRIRESIQEDLAEEAPCPQGGRASGLGEAGMGAWLRAIGLERYEEGLVHNGWDDLE 1225

  Fly   112 ICKQIGEIDLDAIGVDNPSHRGKLLKSVRM 141
            ....|.|.||:..||.:|:|:..||.::::
Mouse  1226 FLSDITEEDLEEAGVQDPAHKRLLLDTLQL 1255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34377	NP_001262830.1	SAM_superfamily	84..144	CDD:472832	24/85 (28%)
Inppl1	NP_034697.2	SH2_SHIP	17..119	CDD:198206
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	119..181
		INPP5c_SHIP2-INPPL1	425..728	CDD:197335
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	897..986
		SH3-binding	945..950
		NPXY motif	984..987
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	999..1119		6/19 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1134..1196		11/64 (17%)
		SAM_Ship2	1193..1255	CDD:188890	23/61 (38%)