Protein Alignment CG7084 and SLC22A14

DIOPT Version :9

• Sequence 1: NP_001247235.2
• Gene: CG7084 / 42606
• FlyBaseID: FBgn0038938
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: XP_006713479.2
• Gene: SLC22A14 / 9389
• HGNCID: 8495
• Length: 675
• Species: Homo sapiens
• Alignment Length: 615
• Identity: 135/615 - (21%)
• Similarity: 251/615 - (40%)
• Gaps: 111/615 - (18%)

  Fly     5 KEQANSRKAS------QVSGH---------FSQMDVDDSEFNDPFQALMEKAGNHGRYQ------ 48
            ||:..|:.||      :|:||         ..::....::.:|.|..|::..|..|.:|
Human    89 KEELRSQDASRNLNQHEVAGHPHSWSLEMLLRRLRAVHTKQDDKFANLLDAVGEFGTFQQRLVAL 153

  Fly    49 ----TLYN--FVFVGGLAFSGAMIYMNIILALNIPDHWCTVPGRENTNFSLEEWRDITLPKQADN 107
                ::.:  |:|.....|:....|.|....|.:..|           .|..|..::|:| ||.|
Human   154 TFIPSIMSAFFMFADHFVFTAQKPYCNTSWILAVGPH-----------LSKAEQLNLTIP-QAPN 206

  Fly   108 RGRKTFSNCEMF---QMNFSEITDWSAWNSNLTKTTEACQNGWSYDKTWYESTIPTDHNWVC--- 166
               .:|..|.|:   ..|...|..:.      ...|:.||:||.|......|.| .:.:.||
Human   207 ---GSFLTCFMYLPVPWNLDSIIQFG------LNDTDTCQDGWIYPDAKKRSLI-NEFDLVCGME 261

  Fly   167 -----AKDLFVTNVFVVGRVTEVAGSFILGQMGDSYGRRFVYYISVVFCSLGRL----GSIMCTS 222
                 |:.:|:..:.:        ||.|...:.|..||    |.:::...||.:    |:....|
Human   262 TKKDTAQIMFMAGLPI--------GSLIFRLITDKMGR----YPAILLSLLGLIIFGFGTAFMNS 314

  Fly   223 SYTW----FLIMSGIVGLTVNSLFQSPQ-IIGMEISREEDRSRIAFFQSCGWSIGTTLMPLLYWW 282
            .:.:    |.|...:||..::|:..:.: ::|      |.|:.......|.:::|..|:..:.:.
Human   315 FHLYLFFRFGISQSVVGYAISSISLATEWLVG------EHRAHAIILGHCFFAVGAVLLTGIAYS 373

  Fly   283 LRHWDSFMWLTSIPTAMVLLFSKYV---IESPRWLISKQRFREAIVQLQKIAKINGHRFDMTEKE 344
            |.||.....:..|   :|:.|..|:   .||||||:.|.:.:||...|...|.:|  :..:....
Human   374 LPHWQLLFLVGGI---LVIPFISYIWILPESPRWLMMKGKVKEAKQVLCYAASVN--KKTIPSNL 433

  Fly   345 LAEIYSRDKQDVTYGIASLFAGWRLARNTTIMGFSWCVVAVSYFTLVLFSSRMAGNPFLNFLYQS 409
            |.|:....|:.....:.......:|.:.|.:|...|..|:.:||||.|....:..:.....:..|
Human   434 LDELQLPRKKVTRASVLDFCKNRQLCKVTLVMSCVWFTVSYTYFTLSLRMRELGVSVHFRHVVPS 498

  Fly   410 IVEIPAYVVGRYMGDTYGRRFTNSVSFLISFVTCLPIIVYSTDE-------------RYENLMIY 461
            |:|:||.:...::....||:::.:|:.|.:.:.||.::.....|             ..:::.|.
Human   499 IMEVPARLCCIFLLQQIGRKWSLAVTLLQAIIWCLLLLFLPEGEDGLRLKWPRCPATELKSMTIL 563

  Fly   462 LATFIKFLNALTFFTVNLQCLEIYPTCMRQTGVALGTILANAIGVLAPYLVYLGTTVDIRAPYYI 526
            :....:|..|.|.....|...|:.||.:|.||:.|.::.:.|..:|:  |..:..|..: .|.::
Human   564 VLMLREFSLAATVTVFFLYTAELLPTVLRATGLGLVSLASVAGAILS--LTIISQTPSL-LPIFL 625

  Fly   527 LGVLFLLGGIGALFLPETLHKKLPDTMEEA 556
            ..||.::....:..||||..:.|.:::..:
Human   626 CCVLAIVAFSLSSLLPETRDQPLSESLNHS 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	118/523 (23%)
		MFS	184..542	CDD:119392	85/382 (22%)
SLC22A14	XP_006713479.2	2A0119	141..650	CDD:273328	124/556 (22%)
		MFS	270..641	CDD:119392	86/396 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.010