DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7084 and Slc22a7

DIOPT Version :9

Sequence 1:	NP_001247235.2	Gene:	CG7084 / 42606	FlyBaseID:	FBgn0038938	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_445989.2	Gene:	Slc22a7 / 89776	RGDID:	621699	Length:	535	Species:	Rattus norvegicus

Alignment Length:	557	Identity:	144/557 - (25%)
Similarity:	246/557 - (44%)	Gaps:	70/557 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 FQALMEKAGNHGRYQTLYNFVFVGGLAFSGAMIYMNIILAL---NIPDHWCTVPGRENTNFSLEE 95
            |:.|::|.|..|.:| |.|.|.   :|....::.|:.:|.:   .:|.|.|.:||.. .|.|.::
  Rat     3 FEDLLDKVGGFGPFQ-LRNLVL---MALPRMLLPMHFLLPVFMAAVPAHHCALPGAP-ANLSHQD 62

  Fly    96 -WRDITLPKQADNRGRKTFSNCEMFQMNFSEITDWSAWNSNLTKTTEA--------------CQN 145
             |.:..||::.|.    :||:|..|.        :.....|:|..||.              |..
  Rat    63 LWLEAHLPRETDG----SFSSCLRFA--------YPQTVPNVTLGTEVSNSGEPEGEPLTVPCSQ 115

  Fly   146 GWSYDKTWYESTIPTDHNWVCAK---DLFVTNVFVVGRVTEVAGSFILGQMGDSYGRR---FVYY 204
            ||.||::.:.|||.|:.:.||.:   :...:..|.:|   .:.|:.:.|.:.|.:|||   .|.|
  Rat   116 GWEYDRSEFSSTIATEWDLVCQQRGLNKITSTCFFIG---VLVGAVVYGYLSDRFGRRRLLLVAY 177

  Fly   205 ISVVFCSLGRLGSIMCTSSYTWFLIM-----SGIVGLTVNSLFQSPQIIGMEISREEDRSRIAFF 264
            :|.:...|....||    :|..|::.     |.:.|.|:..|   |  :.:|....|.|:.....
  Rat   178 VSSLVLGLMSAASI----NYIMFVVTRTLTGSALAGFTIIVL---P--LELEWLDVEHRTVAGVI 233

  Fly   265 QSCGWSIGTTLMPLLYWWLRHWDSFMWLTSIPTAMVLLFSKYVIESPRWLISKQRFREAIVQLQK 329
            .:..||.|..|:.|:.:.:|.|...:...::|....::...:|.||.|||:::.|..||...|..
  Rat   234 STVFWSGGVLLLALVGYLIRSWRWLLLAATLPCVPGIISIWWVPESARWLLTQGRVEEAKKYLLS 298

  Fly   330 IAKINGH---RFDMTEKELAEIYSRDKQDVTYGIASLFAGWRLARNTTIMGFSWCVVAVSYFTLV 391
            .||:||.   ...::::.|..:.:.::.........||...:|...:......|..|..||:.|.
  Rat   299 CAKLNGRPVGEGSLSQEALNNVVTMERALQRPSYLDLFRTSQLRHISLCCMMVWFGVNFSYYGLT 363

  Fly   392 LFSSRMAGNPFLNFLYQSIVEIPAYVVGRYMGDTYGRRFTNSVSFL---ISFVTCLPIIVYSTDE 453
            |..|.:..|.:...|....||:|:.::..::....|||.|.:...|   ::|.|.|.:.:.:
  Rat   364 LDVSGLGLNVYQTQLLFGAVELPSKIMVYFLVRRLGRRLTEAGMLLGAALTFGTSLLVSLET--- 425

  Fly   454 RYENLMIYLATFIKFLNALTFFTVNLQCLEIYPTCMRQTGVALGTILANAIGVLAPYLVYLGTTV 518
              ::.:..|....|..:...|.|..|...|:|||.:||||:.|..::......||| |..|...|
  Rat   426 --KSWITALVVVGKAFSEAAFTTAYLFTSELYPTVLRQTGLGLTALMGRLGASLAP-LAALLDGV 487

  Fly   519 DIRAPYYILGVLFLLGGIGALFLPETLHKKLPDTMEE 555
            .:..|....|.:.|:....||.||||...:||:|:::
  Rat   488 WLLLPKVAYGGIALVAACTALLLPETKKAQLPETIQD 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	133/522 (25%)
CG7084	NP_001247235.2	MFS	184..542	CDD:119392	93/371 (25%)
Slc22a7	NP_445989.2	2A0119	11..521	CDD:273328	140/544 (26%)
Slc22a7	NP_445989.2	MFS	144..511	CDD:119392	95/384 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.020