Protein Alignment CG7084 and TPO1

DIOPT Version :10

• Sequence 1: NP_651016.1
• Gene: CG7084 / 42606
• FlyBaseID: FBgn0038938
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_013072.1
• Gene: TPO1 / 850631
• SGDID: S000003951
• Length: 586
• Species: Saccharomyces cerevisiae
• Alignment Length: 460
• Identity: 89/460 - (19%)
• Similarity: 156/460 - (33%)
• Gaps: 121/460 - (26%)

  Fly   154 YESTI--PTD----HNWVCAKDLF-------------------------VTNVFVVGRVTEVAG- 186
            ||.|.  |.|    .||...|.:.                         :..::.|..|..:.|
Yeast   124 YEVTFDGPNDPLHPFNWPMKKKVLLCLVLCLDSIAIAMCSSIFASAVPQICEIYHVIEVVAILGI 188

  Fly   187 -SFILG---------QMGDSYGRRFVYYISVVFCSLGRLGSIMCTSSYTWFL--IMSGIVGLTVN 239
             .|:||         .:.:.|||:.|..:|....:|.:.......:..|.|:  ...|.:|....
Yeast   189 TLFVLGFAASPVIYAPLSELYGRKGVLVLSAFGFALFQFAVATAENLQTIFICRFFGGFIGAAPM 253

  Fly   240 SLFQSPQIIGMEISREEDRSRIAFFQSCGWSIGTTLMPLLYWWLRHWDSFMWL--------TSIP 296
            ::.  |...............||.| |.|..:|..|.|::..::....::.||        :::.
Yeast   254 AVV--PAAFADMFDTNVRGKAIALF-SLGVFVGPILSPVMGSYIAQRTTWRWLEYVVGCFASAVF 315

  Fly   297 TAMVLLFSKYVIESPRWLISKQRFREAIVQLQKIAKINGHRFDMTEKELAEIYSRDKQDVTYGIA 361
            .|:||.|.:  ...|..|::|.:      |::|.:...|......:.||: |....::.||..|.
Yeast   316 VAIVLFFEE--THHPTILVNKAK------QMRKQSNNWGIHAAHEDVELS-IKDIVQKTVTRPII 371

  Fly   362 SLFAGWRLARNTTIMGFSWCVVAVSYFTLVLFSSRMAGNPFLNFLYQSIVEIPAYVVGRYMGDTY 426
            .||                  |......:.:::|.:.|     .||..:...|...|     :.|
Yeast   372 MLF------------------VEPLLLFVTIYNSFVYG-----ILYLLLEAYPLVFV-----EGY 408

  Fly   427 GRRFTNS-----VSFLISFVTCLPIIVYSTDE-----RYENLMIYLATFIKFLNALTFFTVNLQ- 480
            |  ||.:     ::.:|..:.|...|.|..::     |.:..::..|.....:.|.|.|.:.:.
Yeast   409 G--FTENGELPYIALIIGMMVCAAFIWYMDNDYLKRCRAKGKLVPEARLYAMVIAGTVFPIGILW 471

  Fly   481 -CLEIY---------PTCMRQTGVALGTILANAIGVLAPYLVYLGTTVDIRAPYYILGVLFLLGG 535
             |...|         ||.   .|..:|..|   :|:..|.|.|:..:..:.|...:....|:...
Yeast   472 FCWTGYYPHKIHWMVPTV---GGAFIGFGL---MGIFLPCLNYIIESYLLLAASAVAANTFMRSA 530

  Fly   536 IGALF 540
            .||.|
Yeast   531 FGACF 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7084	NP_651016.1	MFS_SLC22	146..542	CDD:340875	89/460 (19%)
TPO1	NP_013072.1	MFS_Tpo1_MDR_like	156..577	CDD:340881	81/428 (19%)