DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7084 and oct2

DIOPT Version :9

Sequence 1:	NP_001247235.2	Gene:	CG7084 / 42606	FlyBaseID:	FBgn0038938	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_001107932.1	Gene:	oct2 / 797890	ZFINID:	ZDB-GENE-080204-92	Length:	554	Species:	Danio rerio

Alignment Length:	583	Identity:	151/583 - (25%)
Similarity:	270/583 - (46%)	Gaps:	75/583 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 FQALMEKAGNHGRYQ-----------TLYNFVFVGGLAFSGAMIYMNIILALNIPDHWC-TVPGR 86
            |..|::.||:.|.||           .|..||.: |:.|.|           ..||||| |...:
Zfish     4 FDELLQHAGDFGFYQKRISVLGSLPILLLAFVLI-GVVFLG-----------YTPDHWCKTASLQ 56

  Fly    87 ENTNFSLEEWRDITLPKQADNRGRKTFSNCEMFQMNFSEITDWSAWNSNLT---KTT--EACQNG 146
            |...||.|:.||:|:|:..   .|..||.|..|.   ..:.:.||.:.|::   .:|  .||..|
Zfish    57 EKCGFSEEQVRDLTVPRTG---ARGAFSKCVKFD---DALRNGSALSCNISIFNNSTHLSACNEG 115

  Fly   147 WSYDKTWYESTIPTDHNWVCAKDLFVTNVFVVGRVTEVAGSF-----ILGQMGDSYGRRFVYYIS 206
            |::::.  .:||.|:.:.|| :|.::.::..|    .:||.|     :.|.:.|.:||:..:..|
Zfish   116 WTFNEN--RTTIVTEFSLVC-EDSWLADLNQV----SLAGGFFIGALVTGYLADRFGRKSCFIAS 173

  Fly   207 VVFCSLGRLGS-IMCTSSYTWFLIMSGIVGLTVNSLFQSPQIIGMEISREEDRSRIAFFQSCGWS 270
            :.  .||..|: |:.:..|...|....:.|......:.:..::.:|.....:|..::......:|
Zfish   174 IF--GLGVSGTCIIFSPYYPLLLFFRCLQGFFAKGAWTATYVLIIEFFGSNNRKFVSVMSRTFYS 236

  Fly   271 IGTTLMPLLYWWLRHWDSFMWLTSIPTAMVLLFSKYVIESPRWLISKQRFREAIVQLQKIAKING 335
            :|..|:|.|.:::..|.:.....::||.:.|::...:.||||||:|:::.:||:..::.|||.|.
Zfish   237 LGLVLLPALAYYIPSWRNLQLAMTLPTFIFLIYHWVIPESPRWLLSQRKTKEALSIVKSIAKCNK 301

  Fly   336 -------HRFDMTEKELAEIYSRDKQDVTYGIASLFAGWRLARNTTIMGFSWCVVAVSYFTLVLF 393
                   |..|:..::..||.....:|       ||...::.::|.|:.::|...||.:..|||.
Zfish   302 RSLPEDFHEMDLLIEKQEEIMRPSYKD-------LFKTPKMRKHTFILIYAWFTGAVVFQGLVLR 359

  Fly   394 SSRMAGNPFLNFLYQSIVEIPAYVVGRYMGDTYGRRFTNSVSFLISFVTCLPIIVYSTDERYENL 458
            ......|.||:||..::||:|..::..::.|..|||...:....|....||.:...|.:..:  |
Zfish   360 LGITGDNVFLDFLISAVVELPTGLIFYFLVDRIGRRPLMATVNFIGGAACLAVPFISPNISW--L 422

  Fly   459 MIYLATFIKFLNALTFFTVNLQCLEIYPTCMRQTGVALGTILANAIGVLAPYLVYLGTTVDIRAP 523
            ...:|...:...|:...|||....|:|||.:|..||::.:..::...|:||:::|...::....|
Zfish   423 RRTIAIVGRLAVAIGNETVNFANTELYPTPLRNLGVSVCSSASDIGAVVAPFILYRLASIWQELP 487

  Fly   524 YYILGVLFLLGGIGALFLPETLHKKLPDTMEE-----AGHFGKHDKFFSLPK----PPQAAEK 577
            ..:.||:.:|.....:.|||.....||:|:::     :.|..|.......|:    |.:|.||
Zfish   488 LLVYGVMSVLYSGLVMLLPEMKGVDLPETVDDVENLRSRHKRKEKDGAQFPEINIVPMKAVEK 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	130/506 (26%)
CG7084	NP_001247235.2	MFS	184..542	CDD:119392	91/370 (25%)
oct2	NP_001107932.1	2A0119	12..516	CDD:273328	140/539 (26%)
oct2	NP_001107932.1	MFS	123..506	CDD:119392	98/398 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	7.020