Protein Alignment CG7084 and SLC22A1

DIOPT Version :9

• Sequence 1: NP_001247235.2
• Gene: CG7084 / 42606
• FlyBaseID: FBgn0038938
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: XP_005267159.1
• Gene: SLC22A1 / 6580
• HGNCID: 10963
• Length: 610
• Species: Homo sapiens
• Alignment Length: 600
• Identity: 153/600 - (25%)
• Similarity: 249/600 - (41%)
• Gaps: 125/600 - (20%)

  Fly    25 VDDSEFNDPFQALMEKAGNHGRYQTLYNFVFVGGLAFSGAMIYMNIILALNIPDHWCTVPG---- 85
            |||         ::|:.|..|.:|. ..|:.:..|:.:.|.|.:.|:.....|||.|..||
Human     4 VDD---------ILEQVGESGWFQK-QAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAEL 58

  Fly    86 RENTNFSLEEWRDITLPKQADNRGRKTFSNCEMFQMNFSEITDWSAWNSNLTKTTE--------- 141
            .:...:|..|..:.|:|.... .|......|..::::         ||.:.....:
Human    59 SQRCGWSPAEELNYTVPGLGP-AGEAFLGQCRRYEVD---------WNQSALSCVDPLASLATNR 113

  Fly   142 ------ACQNGWSYDKTWYESTIPTDHNWVCAK----DLFVTNVFVVGRVTEVAGSFILGQMGDS 196
                  .||:||.||..  .|:|.|:.|.|||.    |||.:.:    ....:.||..:|...|.
Human   114 SHLPLGPCQDGWVYDTP--GSSIVTEFNLVCADSWKLDLFQSCL----NAGFLFGSLGVGYFADR 172

  Fly   197 YGRRFVYYISVVFCSLGRL------GSIMCTS-SYTWFLIMSGIVGLTVNSLFQSPQIIGMEISR 254
            :||:        .|.||.:      |.:|..| :|...|:...:.||.....:.:...:..|...
Human   173 FGRK--------LCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVG 229

  Fly   255 EEDRSRIAFFQSCGWSIGTTLMPLLYWWLRHWDSFMWLTSIPTAMVLLFSKYVIESPRWLISKQR 319
            ...|..:|......:::|...:..|.:.|.||.......|:||.:.||:...|.||||||:|::|
Human   230 SGSRRTVAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKR 294

  Fly   320 FREAIVQLQKIAKINGH-----------RFDMTEKELAEIYSRDKQDVTYGIASLFAGWRLARNT 373
            ..|||..:..||:.||.           ..|:|||            ::...|.||...||.:.|
Human   295 NTEAIKIMDHIAQKNGKLPPADLKMLSLEEDVTEK------------LSPSFADLFRTPRLRKRT 347

  Fly   374 TIMGFSWCVVAVSYFTLVLFSSRMAGNPFLNFLYQSIVEIPAYVVGRYMGDTYGRRFTNSVSFLI 438
            .|:.:.|...:|.|..|:|.....:||.:|:|||.::||||...:.....|..||.:..::|.|:
Human   348 FILMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLL 412

  Fly   439 SFVTCLPIIVYSTDERYENLMIYLATFIKFLNALTFFTVNLQCL---EIYPTCMRQTGVALGTIL 500
            :...||.:|..|.|..:.|::|.....:....|     :.:.||   |:|||.:|..||.:.:.|
Human   413 AGAACLVMIFISPDLHWLNIIIMCVGRMGITIA-----IQMICLVNAELYPTFVRNLGVMVCSSL 472

  Fly   501 ANAIGVLAPYLVYLGTTVDIRAPYYILGVLFLLGGIGALFLPETLHKKLPDTMEEAGHFGKHDKF 565
            .:..|::.|::|:     .:|..:..|.::        ||     .|:.|          |..:|
Human   473 CDIGGIITPFIVF-----RLREVWQALPLI--------LF-----EKQSP----------KKTRF 509

  Fly   566 F--SLPKPPQAAEKD 578
            .  |.|:.|:|.|:|
Human   510 TLRSKPQNPRAPERD 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	136/531 (26%)
		MFS	184..542	CDD:119392	101/378 (27%)
SLC22A1	XP_005267159.1	2A0119	12..499	CDD:273328	137/541 (25%)
		MFS	118..484	CDD:119392	112/396 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	6.020