DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7084 and Slc22a17

DIOPT Version :9

Sequence 1:	NP_001247235.2	Gene:	CG7084 / 42606	FlyBaseID:	FBgn0038938	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_001347335.1	Gene:	Slc22a17 / 59049	MGIID:	1926225	Length:	520	Species:	Mus musculus

Alignment Length:	508	Identity:	112/508 - (22%)
Similarity:	187/508 - (36%)	Gaps:	119/508 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 FSNCEMFQMNFSEITDWSAWNSNLTKTTEA-------CQNGWSYDKTWYESTIPTDHNWVCAKDL 170
            |::|         :.||. :|.....||.|       |..||.                |..:.:
Mouse    67 FNHC---------LKDWD-YNGLPVLTTNAIGQWDLVCDLGWQ----------------VILEQI 105

  Fly   171 FVTNVFVVGRVTEVAGSFILGQMGDSYGRRFVYYISVVFCSLGRLGSI----MCTSSYTWFLIMS 231
                :|::|   ..:|...||...|.:|||     .:|..:||.:|..    ....|.|..:.:.
Mouse   106 ----LFILG---FASGYLFLGYPADRFGRR-----GIVLLTLGLVGPCGVGGAAAGSSTGIMALR 158

  Fly   232 GIVGLTVNSLFQSPQIIGMEISREEDRSRIAFFQSCGWSIGTTLMPLLYWWLRHWDSFMWLTSIP 296
            .::|..:..:.....::.:|:.....|.|:|.........|..|...|....:.|   .:|..:.
Mouse   159 FLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHFLFLGLALVSKDW---RFLQRMI 220

  Fly   297 TAMVLLFSKY-----VIESPRWLISKQRFREAIVQLQKIAKINGHRFDMTEKELAEIYSRDKQDV 356
            ||..:||..|     .:||.||||.|::..||...|:.:|:.|.....|..:|..|.....:...
Mouse   221 TAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQELENTC 285

  Fly   357 ------TYGIASLFAGWRLARNTTIMGFS--------WCVVAVSYFTLVLFSSRMAGNPFLNFLY 407
                  |:..|||.....:.:|..|:||:        .|...|.          ..|:|...:|.
Mouse   286 PLPATSTFSFASLLNYRNIWKNLLILGFTNFIAHAIRHCYQPVG----------GGGSPSDFYLC 340

  Fly   408 QSIVEIPAYVVGRYMG---DTYGRRFTNSVSFLISFVTCLPIIVYSTDERYENLMIYLATFIKFL 469
            ..:....|.:...::|   |.:|||....:|..::.:..|.::         .|..||..
Mouse   341 SLLASGTAALACVFLGVTVDRFGRRGILLLSMTLTGIASLVLL---------GLWDYLND----- 391

  Fly   470 NALTFFTV-------------NLQCLEIYPTCMRQTGVALGTILA-NAIGVLA--PYLVYLGTTV 518
            .|:|.|:|             .|...|:.||.:|  |..||.|:| .|:|.|:  ...:::|...
Mouse   392 AAITTFSVLGLFSSQASAILSTLLASEVIPTTVR--GRGLGLIMALGALGGLSCPAQRLHMGHGA 454

  Fly   519 DIRAPYYILGVLFLLGGIGALFLPETLHKKLPDTMEEAGHFGKHDKFFSLPKP 571
            .::  :.:|....||..:..:.||||..|.||:.:.: |...:.......|.|
Mouse   455 FLQ--HVVLAACALLCILSIMLLPETKRKLLPEVLRD-GELCRRPSLLRQPPP 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	109/487 (22%)
CG7084	NP_001247235.2	MFS	184..542	CDD:119392	88/399 (22%)
Slc22a17	NP_001347335.1	MFS_SLC22A17	63..476	CDD:341003	102/477 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100