Protein Alignment CG7084 and SLC22A11

DIOPT Version :9

• Sequence 1: NP_001247235.2
• Gene: CG7084 / 42606
• FlyBaseID: FBgn0038938
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_060954.1
• Gene: SLC22A11 / 55867
• HGNCID: 18120
• Length: 550
• Species: Homo sapiens
• Alignment Length: 584
• Identity: 144/584 - (24%)
• Similarity: 240/584 - (41%)
• Gaps: 122/584 - (20%)

  Fly    34 FQALMEKAGNHGRYQTLYNFVFV-GGLAFSGAMIYMNIILALNIPDHWCTVPGREN-----TNFS 92
            |..|:|:||..|.:|||....|: ..|.....|:..|...|  ||.|.|.....:|     ||.:
Human     3 FSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAA--IPGHRCWTHMLDNGSAVSTNMT 65

  Fly    93 LEEWRDITLPKQADNRGRKTFSNCEMFQMNFSEITDWSAWNSNLTKT------TEACQNGWSYDK 151
            .:....|::| ...|:|.   ..|..|:.     ..|...:.|.|.|      ||.|.:||.||:
Human    66 PKALLTISIP-PGPNQGP---HQCRRFRQ-----PQWQLLDPNATATSWSEADTEPCVDGWVYDR 121

  Fly   152 TWYESTIPTDHNWVC--------AKDLFVTNVFVVGRVTEVAGSFILGQMGDSYGRR-------- 200
            :.:.|||....:.||        ::.:|::.:.|        ||||.|.:...:||:
Human   122 SVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILV--------GSFIWGLLSYRFGRKPMLSWCCL 178

  Fly   201 --------------FVYYISVVFCSLGRLGSIMCTSSYTWFLIMSGIVGLTVNSLFQSPQIIGME 251
                          |     |::|.|.             |:...|:.|:.::||     .:.:|
Human   179 QLAVAGTSTIFAPTF-----VIYCGLR-------------FVAAFGMAGIFLSSL-----TLMVE 220

  Fly   252 ISREEDRSRIAFFQSCGWSIGTTLMPLLYWWLRHWDSFMWLTSIPTAMVLLFSKYVIESPRWLIS 316
            .:....|:.......|.:|.|...:..|.:.||.|.:.....|:|...:.|.|.::.||.||||.
Human   221 WTTTSRRAVTMTVVGCAFSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLII 285

  Fly   317 KQRFREAIVQLQKIAKINGHRFDMTEKELAEIYSRDKQDVT-----YGIASLFA----GWRLARN 372
            |.:..:|:.:|:|:|:||||: :.....:..:.|..|::|.     ..:..||.    .||...
Human   286 KGKPDQALQELRKVARINGHK-EAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCA- 348

  Fly   373 TTIMGFSWCVVAVSYFTLVLFSSRMAGNPFLNFLYQSI---VEIPAYVVGRYMGDTYGRRFTNSV 434
            ..::.||   :.:||:.|| |..:..|...  ||.|::   |:.........:....|||...:.
Human   349 MLVVNFS---LLISYYGLV-FDLQSLGRDI--FLLQALFGAVDFLGRATTALLLSFLGRRTIQAG 407

  Fly   435 SFLISFVTCLPIIVYSTDERYENLMIYLATFIKFLNALTFFTVNLQCL-----EIYPTCMRQT-- 492
            |..::.:..|..::...|  .:.|.:..|...|     ..|.::|.||     |::||.:|.|
Human   408 SQAMAGLAILANMLVPQD--LQTLRVVFAVLGK-----GCFGISLTCLTIYKAELFPTPVRMTAD 465

  Fly   493 GVALGTILANAIGVLAPYLVYLGTTVDIRAPYYILGVLFLLGGIGAL-FLPETLHKKLPDTMEE 555
            |: |.|:  ..:|.:...|:.:........|..:.||:.:...:..| |||||....||||:::
Human   466 GI-LHTV--GRLGAMMGPLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQD 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	131/548 (24%)
		MFS	184..542	CDD:119392	91/399 (23%)
SLC22A11	NP_060954.1	Sugar_tr	11..523	CDD:331684	138/571 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	531..550

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	6.020