DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7084 and slc22a16

DIOPT Version :9

Sequence 1:	NP_001247235.2	Gene:	CG7084 / 42606	FlyBaseID:	FBgn0038938	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_001020659.1	Gene:	slc22a16 / 557279	ZFINID:	ZDB-GENE-041001-166	Length:	565	Species:	Danio rerio

Alignment Length:	581	Identity:	140/581 - (24%)
Similarity:	254/581 - (43%)	Gaps:	97/581 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 QALMEKAGNHGRYQTLYNFVFVGGLAFSGAMIYMNIILALNIPDHWCTVPGRENTNFSLEEWRDI 99
            :.|.::.|:..|:|....|..: ..|.|..:.|:..:..:..|...|..|    .|.:...::::
Zfish     6 ERLFDELGHFKRFQACLYFAAI-FQAISCGIHYLASVFLVETPKFLCNPP----LNITDVLYKNL 65

  Fly   100 TLPKQAD----------------NRGRK-TFSNC----EMFQMNFSEITDWSAWNSNLTKTTEAC 143
            :....||                ::|.: ..|.|    .:..:||.       :.....|:.|:|
Zfish    66 SFTSLADIWTHYKTGDGPVVVRTSQGDQWELSPCLKALRLDAINFQ-------YEFFGNKSVESC 123

  Fly   144 QNGWSYDKTWYESTIPTDHNWVCAKD---LFVTNVFVVGRVTEVAGSFILGQMGDSYGRR----- 200
             ..:.||.:..|.:|.||.:.||.::   ......|::|   .:.|:.:.|...|..|||
Zfish   124 -GAFVYDHSEVEQSIVTDWDLVCEREWLAKLTQPTFMLG---VLIGALMFGDAADRIGRRPVLMA 184

  Fly   201 -----FVYYISVVFCSLGRLGSIMCTSSYTWFLIMSGIVGLTVNS------LFQSPQIIGMEISR 254
                 |::.::|.|           |.:|..|::|..::. ||:|      .....:..|:::
Zfish   185 TSLCQFIFGVTVAF-----------TGNYYLFVVMRFLLA-TVSSGYLVVVFVYVTEFTGIKV-- 235

  Fly   255 EEDRSRIAFFQSCGWSIGTTLMPLLYWWLRHWDSFMWLTSIPTAMVLLFSKYVIESPRWLISKQR 319
               |:..:......:::|..::.|:.:.:|.|..:..:.::.|:..||:.....|:|.:|::|.|
Zfish   236 ---RTWTSMHVHAAFAVGIMVVALVGYLVRVWWIYQIILTLSTSPFLLYCWKFPETPFYLMAKGR 297

  Fly   320 FREAIVQLQKIAKING-----------HRFDMT----EKELAEIYSRDKQDVTYGIASLFAGWRL 369
            ::||...|..:|.|||           ...|.|    .|:..|:..|      ..:..:|...::
Zfish   298 YKEAQELLDTMAYINGLPPTLKVSDLQDGCDRTPLKDNKQAMEVEKR------LSMLDMFGSLKM 356

  Fly   370 ARNTTIMGFSWCVVAVSYFTLVLFSSRMAGNPFLNFLYQSIVEIPAYVVGRYMGDTYGRRFTNSV 434
            |..:......|.:.::.|:...|.|..:.||.::|......||:|:|::|.:..|.:||:.|.:.
Zfish   357 AGRSATCWAIWFIGSLGYYVFSLGSVNLGGNQYINLFLAGAVEVPSYLIGCFAMDRFGRKKTCAP 421

  Fly   435 SFLISFVTCLPIIVYSTDERYENLMIYLATFIKFLNALTFFTVNLQCLEIYPTCMRQTGVALGTI 499
            :.|:..|.|:.|||...|  .|.|.|.|:...||..|:.|..:.|...|:|||.:|...|..|::
Zfish   422 ALLLGGVACMLIIVVPQD--VEVLAIVLSMTGKFAIAIAFGLIYLYTCELYPTIIRSLAVGSGSM 484

  Fly   500 LANAIGVLAPYLVYLGTTVDIRAPYYILGVLFLLGGIGALFLPETLHKKLPDTMEEAGHFG 560
            :.....|:||:.||| ..:.|..|..|:|:|..:.||..:||||||.:.|..|:|||...|
Zfish   485 MCRVGSVVAPFCVYL-ADIWIYLPQLIVGILAFIIGILTMFLPETLGEPLTSTLEEAEALG 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	128/542 (24%)
CG7084	NP_001247235.2	MFS	184..542	CDD:119392	97/388 (25%)
slc22a16	NP_001020659.1	2A0119	13..536	CDD:273328	134/564 (24%)
slc22a16	NP_001020659.1	MFS	158..526	CDD:119392	99/396 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.920