DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7084 and slc22a15.1

DIOPT Version :9

Sequence 1:	NP_001247235.2	Gene:	CG7084 / 42606	FlyBaseID:	FBgn0038938	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	XP_031751719.1	Gene:	slc22a15.1 / 448510	XenbaseID:	XB-GENE-959503	Length:	560	Species:	Xenopus tropicalis

Alignment Length:	560	Identity:	129/560 - (23%)
Similarity:	230/560 - (41%)	Gaps:	101/560 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 QMDVDDSEFNDPFQALMEKAGNHGRYQTLYNFVFVGGL-AFSGAMIYMNIILALNIPDHW----C 81
            ||:|:.:         ::..|..|.||...:|:....| .:|.....:..||....|.||    .
Frog    26 QMEVEGA---------LKLVGEMGIYQIYLSFLLAVLLQLYSATEAIIITILGATPPYHWMNDSL 81

  Fly    82 TVPGRENTNFSLEEWRDITLPKQADNRGRKTFSNCEMFQMNFSEITDWSAWNSNLTKTTEACQNG 146
            |..|.....:..:      ||.:.:: |...|..      ||:.|.  |.|         ....|
Frog    82 TANGSRGKQYGSQ------LPAEGEH-GHVVFDG------NFTSIV--SEW---------FLVGG 122

  Fly   147 WSYDKTWYESTIPTDHNWVCAKDLFVTNVFVVGRVTEVAGSFILGQMGDSYGRRFVYY----ISV 207
            .:|                   ::.|::....|.|  :.|....||:.|.:||:.||.    :.|
Frog   123 AAY-------------------EVSVSSSVYFGGV--LIGVISFGQLSDRFGRKPVYVTGLALEV 166

  Fly   208 VFCSLGRLGSIMCTSSYTWFL--IMSGIVGLTVNSLFQSPQIIGMEISREEDRSRIAFFQSCG-- 268
            ||..:..|..|......|.||  :|:|  |:::.:.....:.||           .:::.:.|
Frog   167 VFAVMNALTPIFPLFLLTRFLVGVMNG--GMSLVAFVLLNECIG-----------ASYWAAAGSL 218

  Fly   269 ----WSIGTTLMPLLYWWLRHWDSFMWLTSIPTAMVLLFSKYVIESPRWLISKQRFREAIVQLQK 329
                :::|.....|:.:::|.|.....|.::..|.||..|..:.||||||.::.|.|||...|..
Frog   219 GSLCFAVGIAQFALIGYFIRSWRLLALLVNVQGAAVLALSLCIPESPRWLHAQGRLREAQESLLS 283

  Fly   330 IAKINGHR---FDMTEKELAEIYSRDKQDVTYGIASLFAGWRLARNTTIMGFSWCVVAVSYFTLV 391
            :.:.|..:   |.:..::....:|.:       |.::::...|.:.|.||.:.|.|.::.|:.|.
Frog   284 LGRRNRRKVTSFTLCPRQKDSAHSAN-------ILTIYSNAILRQRTLIMMWVWFVCSLVYYGLT 341

  Fly   392 LFSSRMAGNPFLNFLYQSIVEIPAYVVGRYM--GDTYGRRFTNSVSFLISFVTCLPIIVYSTDER 454
            |.|..:.|:.:||.....:.|:|||.:..|:  ....|||.:.:....:....||.|::......
Frog   342 LSSGDLGGDIYLNLALSGLAELPAYPLCMYLINHKRVGRRGSLAGFLCVGGGACLLIMLVPGKTG 406

  Fly   455 YENLMIYLATFIKFLNAL----TFFTVNLQCLEIYPTCMRQTGVALGTILANAIGVLAPYLVYLG 515
            ...|.:..:..:..|..|    .|..|.:...|:||||:|..|:.:.::.:...|::||::..|
Frog   407 SGPLSVLNSQTLSLLGKLNISAAFNIVYIYSSELYPTCVRNLGMGVCSMFSRIGGIIAPFIPAL- 470

  Fly   516 TTVDIRAPYYILGVLFLLGGIGALFLPETLHKKLPDTMEE 555
            .......|:.:.|...:..|:.:|.|||||...||:|:.:
Frog   471 RFAHWALPFIVFGAAGVSAGLLSLLLPETLSAPLPETLAD 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	118/512 (23%)
CG7084	NP_001247235.2	MFS	184..542	CDD:119392	90/378 (24%)
slc22a15.1	XP_031751719.1	MFS	90..497	CDD:421695	104/472 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920