DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7084 and CG6126

DIOPT Version :9

Sequence 1:	NP_001247235.2	Gene:	CG7084 / 42606	FlyBaseID:	FBgn0038938	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_650528.1	Gene:	CG6126 / 41967	FlyBaseID:	FBgn0038407	Length:	555	Species:	Drosophila melanogaster

Alignment Length:	581	Identity:	151/581 - (25%)
Similarity:	261/581 - (44%)	Gaps:	80/581 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 LMEKAGNHGRYQTLYNFVFV-GGLAFSGAMIYMNIILALNIPDHWCTVPGRENTNFSLEEWRDIT 100
            ||.|.|..|:||.|..|:.| .||  :..|..::::....:|:|.|.:.|.:|::.|:..|....
  Fly    10 LMGKLGEFGKYQFLQFFLQVLSGL--TAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSVTPWNSSA 72

  Fly   101 LPKQADNRGRKTFSNCEMFQMNFSEITDWSAWNSNLTKTTEACQNGWSYDKTWYESTIPTDHNWV 165
            :......:......:|.||..           :|..|.||..|:. :.||.|:|:::...|.|:|
  Fly    73 ILAAIPLKPNGELESCLMFDP-----------SSPGTNTTINCER-YVYDTTYYKTSRTIDWNFV 125

  Fly   166 CAK---DLFVTNVFVVGRVTEVAGSFILGQMGDSYGRRFVYYISVVFCSLGRLGSIMCTSSYTWF 227
            |.:   ...|..||::|..|   |:..||.:.|..||:.|:..|.:|..:..:| :.....|..|
  Fly   126 CDRRWMGAIVQTVFMLGVFT---GAVTLGGLADKVGRKTVFCWSALFQLIIGVG-VAFIPEYFSF 186

  Fly   228 LI---MSGIVGLTVNSLFQSPQIIGMEISREEDRSRIAF-FQS---------CGWSIGTTLMPLL 279
            ::   :.||||..  ..:....::.||:.....|:.... ||:         .||.   .|:|..
  Fly   187 MVARYLLGIVGSA--GAYICGFVLTMELVGPTKRTVCGITFQAVFAGGIMLVAGWG---ALIPDR 246

  Fly   280 YW-----------WLRHWDSFMWLTSIPTAMVLLFSKYVIESPRWLISKQRFREAIVQLQKIAKI 333
            .|           :|.||   .||.               ||||||..:.|..||:..:.|..:|
  Fly   247 QWLQVIYGLHGCLFLGHW---WWLD---------------ESPRWLWMQGRAAEAVDIVAKGLRI 293

  Fly   334 NGHRFDMTEK---ELAEIYSRDKQDVTYGIASLFAGWRLARNTTIMGFSWCVVAVSYFTLVLFSS 395
            ||....:.::   :.|:..:..::..:.|::.||....|...|..:...|...::.|:.|.|.:.
  Fly   294 NGSGIPVDKEYYVQKAKQQAAAEEKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLVYYGLSLSAG 358

  Fly   396 RMAGNPFLNFLYQSIVEIPAYVVGRYMGDTYGRRFTNSVSFLISFVTCLPIIVYSTDERYENLMI 460
            ::.|||:|......:||.|:|:...::.|..|||...|...|...:.|: :..|.......:..:
  Fly   359 KLYGNPYLILFIMGLVEFPSYITIVFVLDRLGRRSITSTLMLGGGLCCI-VAAYIAQGSTTSTAV 422

  Fly   461 YLATFIKFLNALTFFTVNLQCLEIYPTCMRQTGVALGTILANAIGVLAPYLVYLGTTVDIRAPYY 525
            .:|.  |.|.|.:|..:.....|::||.:|.:.:.||::.|...|.|.| |:.|..:.|.:.|..
  Fly   423 VMAG--KLLIAGSFAVIYNYSAELFPTVVRNSAMGLGSMCARLSGALTP-LITLLDSFDPKIPAV 484

  Fly   526 ILGVLFLLGGIGALFLPETLHKKLPDTMEEAGHFGKHDKFFSLPKPPQAAEKDDKLSSHPE 586
            :.||:.|:.|...:|||||:::.:|:::|:..:|||.|.:||    ..|..|..:.|.:|:
  Fly   485 LFGVVALISGFWVMFLPETMNQPMPESIEDGENFGKGDTWFS----QCAGRKKRQNSVYPD 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	128/517 (25%)
CG7084	NP_001247235.2	MFS	184..542	CDD:119392	94/384 (24%)
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	136/539 (25%)
CG6126	NP_650528.1	MFS	130..501	CDD:119392	99/401 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	6	6.060