DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7084 and CG7458

DIOPT Version :9

Sequence 1:	NP_001247235.2	Gene:	CG7084 / 42606	FlyBaseID:	FBgn0038938	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_649374.1	Gene:	CG7458 / 40441	FlyBaseID:	FBgn0037144	Length:	572	Species:	Drosophila melanogaster

Alignment Length:	601	Identity:	151/601 - (25%)
Similarity:	266/601 - (44%)	Gaps:	88/601 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRDKKEQANSRKA-SQVSGHFSQM--------DVDDSEFNDPFQALMEKAGNHGRYQTLYNFVFV 56
            |..:||....|:: |:.:||....        |.|:|     ..|::.:.|..|||| :.|:|.:
  Fly     1 MTSQKEGNGYRRSDSKTTGHADAEAATQTAGGDEDNS-----LDAILVRIGQFGRYQ-IINYVLL 59

  Fly    57 GGLAFSGAMIYMNIILALNIPDHWCTVPGRENTNFSLEE-WRDITLPKQADNRGRKTFSNCEMFQ 120
            .......|...::.:...:...|.||||..::.:...|| |...|:||:     ...:.:|..:.
  Fly    60 CVPMLFNAFFSISYVFTASTVVHRCTVPQCDSPSSVYEEDWLGFTIPKK-----NSAWDDCHRYA 119

  Fly   121 MNFSE----ITDWS---AWNSNLTKTTEACQNGWSY-DKTWYESTIPTDHNWVCAKDLFVTNVFV 177
            .|.|:    .||.|   ......|.|:|.|...:.: |:   |.||.|:....|..:..::.|..
  Fly   120 ANISDAISGYTDPSGQYCLKEYFTITSETCGRDFKFRDE---EKTISTEFGIYCEDEWKLSMVGT 181

  Fly   178 VGRVTEVAGSFILGQMGDSYGRRFVYYISVVFCSLGRLGSIM-----CTSSYTWFLIMSGIVGLT 237
            :..|.:..|..:.|...|.||||.:..::      |.:.::|     .:|:|:.||:...:....
  Fly   182 INNVGQFVGIPLGGYFADRYGRRTMLAVA------GSVSALMGVIRSLSSNYSMFLVFEFLDMAV 240

  Fly   238 VNSLFQSPQIIGMEISREEDRSRIAFFQSCGWSIGTTLMPLLYWWLRHWDSFMWLTSI---PTAM 299
            .::||.:..::.:|:...:.|...|...:..:::|...:..|...::||   .||..:   |..:
  Fly   241 GSTLFPTAFLLAIELVGPKRRVAAATIITIFYALGEAFLGFLASQVQHW---RWLLRVLYAPAVL 302

  Fly   300 VLLFSKYVIESPRWLISKQRFREAIVQLQKIAKINGHRFDMTEKELAEIYSRDKQDVT------Y 358
            .:||...:.||.|||:|:....:|...|::.|:||  :..:.|::|.::.:.::|.::      |
  Fly   303 QILFLWILPESVRWLLSQGAEEKASNVLRRAARIN--QRPLPEEQLNDLLTSNRQKLSQANESQY 365

  Fly   359 GI--ASLFAGWRLARNTTIMGFSWCVVAVSYFTLVLFSSRMAGNPFLNFLYQSIVEIPAYVVGRY 421
            .|  |.:|...|:| |..:..|:..::|:.   |.|.|..:.||.:.||:....::||..::...
  Fly   366 PIMRAVVFFSLRIA-NCCLCWFTHTLIALG---LSLNSVNLGGNKYTNFMLNGFIQIPGLLLPLV 426

  Fly   422 MGDTYGRRFTNSVSFLISFVTCLPIIVYSTDERYENLMIY----LATFIKFLNALTFFTVNLQCL 482
            :.|..|||.:...|.|:..:..........|....:|.::    ||....| ..|.|||     .
  Fly   427 IMDRVGRRHSLCASMLLCAICMGASAAVPADNYAGSLALFLIGKLAITCSF-QILYFFT-----S 485

  Fly   483 EIYPTCMRQTGVAL-------GTILANAIGVLAPYLVYLGTTVDIRAPYYILGVLFLLGGIGALF 540
            ||:||.:|.|.::|       |::||....:||.|.:|        ||..:.....|:.|...|.
  Fly   486 EIFPTNVRNTLLSLCSMVGRIGSMLAPQTPLLAKYYIY--------APQILFATFALISGFLTLA 542

  Fly   541 LPETLHKKLPDTMEEA 556
            .|||..|.||.|:|||
  Fly   543 FPETADKVLPTTIEEA 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	129/523 (25%)
CG7084	NP_001247235.2	MFS	184..542	CDD:119392	93/384 (24%)
CG7458	NP_649374.1	2A0119	46..554	CDD:273328	136/545 (25%)
CG7458	NP_649374.1	MFS	161..544	CDD:119392	99/411 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	5.060