Protein Alignment CG7084 and SLC22A25

DIOPT Version :9

• Sequence 1: NP_001247235.2
• Gene: CG7084 / 42606
• FlyBaseID: FBgn0038938
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: XP_016873173.1
• Gene: SLC22A25 / 387601
• HGNCID: 32935
• Length: 577
• Species: Homo sapiens
• Alignment Length: 633
• Identity: 145/633 - (22%)
• Similarity: 242/633 - (38%)
• Gaps: 151/633 - (23%)

  Fly    34 FQALMEKAGNHGRYQTLYNFVFVGGLAFSGAMIYMNIIL---------ALNIPDHWC-------- 81
            ||.|:::.|..||:|.| ..||         :|..|:|:         |..|.||.|
Human     3 FQDLLDQVGGLGRFQIL-QMVF---------LIMFNVIVYHQTQLENFAAFILDHRCWVHILDND 57

  Fly    82 TVPGRENTNFSLEEWRDITLPKQADNRGRKTFSNCEMFQMNFSEITDWSAWNSNLT------KTT 140
            |:|..:....|.:....|::|..::.|..|    |..|..     ..|...:.|.|      ..|
Human    58 TIPDNDPGTLSQDALLRISIPFDSNLRPEK----CRRFVH-----PQWKLIHLNGTFPNTSEPDT 113

  Fly   141 EACQNGWSYDKTWYESTIPTDHNWVC--------AKDLFVTNVFVVGRVTEVAGSFILGQMGDS- 196
            |.|.:||.||::.:.|||.|..:.||        ||.||:..:.|        |..:.|.:.|.
Human   114 EPCVDGWVYDQSSFPSTIVTKWDLVCESQPLNSVAKFLFMAGMMV--------GGNLYGHLSDRK 170

  Fly   197 -----------------------------YGRRFVY---YIS--------------VVFCSLGRL 215
                                         :||:||.   |:.              :|:|||.
Human   171 PLSSPNHVSTDCDEGLEVPIAIHQHHVFWFGRKFVLRWSYLQLAIVGTCAAFAPTILVYCSLR-- 233

  Fly   216 GSIMCTSSYTWFLIMSGIVGLTVNSL-----FQSPQIIGMEISREEDRSRIAFFQSCGWSIGTTL 275
                       ||..:....:.||::     :.:.|...|.::          ...|..|||...
Human   234 -----------FLAGAATFSIIVNTVLLIVEWITHQFCAMALT----------LTLCAASIGHIT 277

  Fly   276 MPLLYWWLRHWDSFMWLTSIPTAMVLLFSKYVIESPRWLISKQRFREAIVQLQKIAKING--HRF 338
            :..|.:.:|.......:.|.|..:..|||:::.||.||||...:..|.:.:|:|.|..||  :..
Human   278 LGSLAFVIRDQCILQLVMSAPCFVFFLFSRWLAESARWLIINNKPEEGLKELRKAAHRNGMKNAE 342

  Fly   339 DMTEKELAEIYSRDKQDV-----TYGIASLFAGWRLARNTTIMGFSWCVVAVSYFTLVLFSSRMA 398
            |:...|:  :.|..||::     .:.:..|.....:.:....:.|......:.::.|.|....:.
Human   343 DILTMEV--LKSTMKQELEAAQKKHSLCELLRIPNICKRICFLSFVRFASTIPFWGLTLHLQHLG 405

  Fly   399 GNPFLNFLYQSIVEIPAYVVGRYMGDTYGRRFTNS-VSFLISFVTCLPIIVYSTDERYENLMIYL 462
            .|.||.......|.:.|..|..:..:...||.:.. :.||::  |||..|::...| .:.|.:.|
Human   406 NNVFLLQTLFGAVTLLANCVAPWALNHMSRRLSQMLLMFLLA--TCLLAIIFVPQE-MQTLRVVL 467

  Fly   463 ATFIKFLNALTFFTVNLQCLEIYPTCMRQTGVALGTILANAIGVLAPYLVYLGTTVDIRAPYYIL 527
            ||......:|.......|..|:.|:.:|.....:....||..|.||..::.| :......|:.|.
Human   468 ATLGVGAASLGITCSTAQENELIPSIIRGRATGITGNFANIGGALASLMMIL-SIYSRPLPWIIY 531

  Fly   528 GVLFLLGGIGALFLPETLHKKLPDTMEEAGHFGKHDKFFSLPKPPQAA 575
            ||..:|.|:..|.||||.::.|.|::::..:.|.:    ||..|.:::
Human   532 GVFAILSGLVVLLLPETRNQPLLDSIQDVENEGVN----SLAAPQRSS 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	130/578 (22%)
		MFS	184..542	CDD:119392	87/417 (21%)
SLC22A25	XP_016873173.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.010