DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7084 and CG42269

DIOPT Version :9

Sequence 1:	NP_001247235.2	Gene:	CG7084 / 42606	FlyBaseID:	FBgn0038938	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_648019.2	Gene:	CG42269 / 38689	FlyBaseID:	FBgn0259164	Length:	662	Species:	Drosophila melanogaster

Alignment Length:	592	Identity:	152/592 - (25%)
Similarity:	273/592 - (46%)	Gaps:	61/592 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 MDVDDSEFNDPFQALMEKAGNHGRYQTLYNFVFVGGLAFSGAMIYMNIILALNIPD-HWCTVPGR 86
            ||.||         ::...|..||||.|. |:.:...:|..|.:|.:.|....||: |||.||
  Fly    70 MDFDD---------ILPLIGEFGRYQKLL-FICMIPFSFFVAFVYFSQIFLTLIPEQHWCHVP-- 122

  Fly    87 ENTNFSLEEWRDITLPKQADNRGRKTFSNCEMFQMNFSEITDWSAWNSNLTKTTEACQNGWSYDK 151
            |.....:|....:::|.   ..|.  ::||.|:.:|:::|.......::.......|::||||:.
  Fly   123 ELDGLDVEARLALSIPM---TNGE--YNNCYMYDVNYTDILAQGKVMADPKWPQVKCRHGWSYNF 182

  Fly   152 TWYE-STIPTDHNWVC---AKDLFVTNVFVVGRVTEVAGSFILGQMGDSYGRRFVYYISVVFCSL 212
            |... :|:.|:.||||   |...:..::|.:|   .:.|..:.|.:.|.:||......:.:...|
  Fly   183 TEIPYATVATEQNWVCDDAALPTYAQSIFFLG---AIVGGLLFGWVADRFGRIPALIGTNMMGLL 244

  Fly   213 GRLGSIMCTSSYTWFLIMSGIVGLTVNSLFQSPQIIGMEISREEDRSRIA------FFQSCGWSI 271
            ..:|:.. .|::..|.||...||...::.|....|:.:|....:.|:.:|      ||..
  Fly   245 AGVGTAF-VSNFWEFAIMRFFVGFAFDNCFTMMYILVLEYVGPKYRTFVANMSIAIFFTG----- 303

  Fly   272 GTTLMPLLYWWLRHWDSFMWLTSIPTAMVLLFSKYVI-ESPRWLISKQRFREAIVQLQKIAKING 335
            ...|:|.:.::|..|.....:||.| .::.:|:.:|: ||.|||:|:.:..:|:..|:|:.|.||
  Fly   304 AACLLPWIAYFLADWKLLAIVTSAP-LLLAIFTPFVVPESARWLVSQGKVDKAVGILKKLEKGNG 367

  Fly   336 HR-----FDMTEKELAEIYSRDKQDVTYGIASLFAGWRLARNTTIMGFSWCVVAVSYFTLVLFSS 395
            .:     :.:.......:..::.|:..|.:..||...||.|.|.::...|..:::.:...|....
  Fly   368 RQVPPQTYQIFTDSCKRMQEQEAQNGKYSVLDLFKSPRLRRTTLLLIVIWMAISLVFDGHVRNVG 432

  Fly   396 RMAGNPFLNFLYQSIVEIPAYVVGRYMGDTYGRRFTNSVSFLISFV-----TCLPIIVYSTDERY 455
            .:..:.|..|......|:||..:...:.|.:|||:....|.::|.|     |.:|:.:||.
  Fly   433 SLGLDIFFTFTLACFTELPADTLLTVILDRFGRRWLACSSMVLSGVFSLLATVVPVGIYSA---- 493

  Fly   456 ENLMIYLATFIKFLNALTFFTVNLQ-CLEIYPTCMRQTGVALGTILANAIGVLAPYLVYLGTTVD 519
                 .||...:|...:: :.:.|| ..|:.||.:|...||...|:.....::||::||| ..:.
  Fly   494 -----ALAIMGRFFVNIS-YNIGLQWAAEVLPTVVRAQAVAFIHIMGYVASIIAPFVVYL-ANIS 551

  Fly   520 IRAPYYILGVLFLLGGIGALFLPETLHKKLPDTMEEAGHFGKHDKFFSLPKPPQAAEKDDKLSSH 584
            ...|..|||:|.::||:.||.|||||:..||.|:.:...||:....:..|...:..:.|:....:
  Fly   552 QALPLIILGILGIIGGLLALLLPETLNHVLPQTLSDGEEFGRGQSIWDFPCLAKQVDDDEDEKRN 616

  Fly   585 PELTRLR 591
            .::..:|
  Fly   617 ADVEEVR 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	134/510 (26%)
CG7084	NP_001247235.2	MFS	184..542	CDD:119392	93/375 (25%)
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	126/500 (25%)
CG42269	NP_648019.2	MFS	206..545	CDD:119392	83/358 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	6	6.060