DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7084 and Slc22a13

DIOPT Version :9

Sequence 1:	NP_001247235.2	Gene:	CG7084 / 42606	FlyBaseID:	FBgn0038938	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_001119757.1	Gene:	Slc22a13 / 316062	RGDID:	1306840	Length:	551	Species:	Rattus norvegicus

Alignment Length:	579	Identity:	130/579 - (22%)
Similarity:	242/579 - (41%)	Gaps:	61/579 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 FQALMEKAGNHGRYQT-------LYNFVFVGGLAFSGAMIYMNIILALNIPDHWCTVPGRENTNF 91
            |..:|.:.|:.||:|.       :.||:       |...::..:.:.|: ..|:|:|...:|..|
  Rat     4 FAQVMAEVGDFGRFQVRLTILMGIPNFL-------SAFFVFSQVFMVLD-EAHYCSVSWVKNHTF 60

  Fly    92 SLEEWRDITLPKQADNRGRKTFSNCEMFQ-----MNFSEITDWSAWNSNLTKTTEACQNGWSYDK 151
            :|.....:.:....|..||.  .:|.||:     .:..:|.      |:....|:||.:||.|.:
  Rat    61 NLSAAEQLAVSIPNDTAGRP--ESCLMFRPPPDNASLEDIL------SHRFNETQACDSGWDYPE 117

  Fly   152 TWYESTIPTDHNWVCAKDLF---VTNVFVVGRVTEVAGSFILGQMGDSYGRRFVYYISVVFCSLG 213
            . ...::..:.:.||.::..   ..:||:.|.   :.|:.:.|.:.|..|||....:.::...:.
  Rat   118 N-RPPSLKNEFDLVCERENLKRTSQSVFMAGL---LVGALVFGPVCDWIGRRPSLLMQLLLSGIA 178

  Fly   214 RLGSIMCTSSYTWFLIMSGIVGLTVNSLFQSPQIIGMEISREEDRSRIAFFQSCGWSIGTTLMPL 278
            .:.:...:|...:..:...:.......|..|..::...:.... |:|........:::|...:..
  Rat   179 SMATAFVSSFELYMTLRFALATANAGFLLSSNVLLSEWVGTSR-RTRAMVLAQSNFALGLMALAG 242

  Fly   279 LYWWLRHWDSFMWLTSIPTAMVLLFSKYVIESPRWLISKQRFREAIVQLQKIAKINGHRFDMTEK 343
            |.:.:|:|.....:.:.|..:::.:...:.||||||:|:.|..||...:||.|.:||...   ..
  Rat   243 LAYGVRNWRLLQIIGTTPIFLLVFYFWVLPESPRWLLSQGRTEEAKQLVQKAALVNGRPL---AS 304

  Fly   344 ELAEIYSRDKQDVTYGIASLFAGWRLARNTTIMGFSWCVVAVSYFTLVLFSSRMAGNPFLNFLYQ 408
            ||......:|...:.....||...:|.:.|.|:...|.|.::.|:.|.........:.:|..:..
  Rat   305 ELLNQLVPEKTGPSGNALDLFRHPQLRKVTLILIAVWFVDSLLYYGLGFQVGDFGLDIYLTQVIF 369

  Fly   409 SIVEIPAYVVGRYMGDTYGRRFTNSVSFLISFVTCLPIIVYSTDERYENLMIYLATFIKFLNALT 473
            .:||:||.:....|.:..||:::...:..::.|.|:.||....|  ...:...||...||.::..
  Rat   370 GVVEVPARLSSIPMMEKLGRKWSQLCTLTLAGVMCVIIIFIPGD--LPTVATALAVVGKFASSAA 432

  Fly   474 FFTVNLQCLEIYPTCMRQTGVALGTILANAIGVLAPYLVYLGTTVDIRAPYYILGVLFLLGGIGA 538
            |....:...|:.||.:||||:.|.:|.:...|::.| ||.|........|..|.|.|.:..|:..
  Rat   433 FTISYVYTAELLPTIIRQTGMGLVSIFSRVGGIITP-LVMLLEQYHKAIPMLIFGSLPIGAGLLC 496

  Fly   539 LFLPETLHKKLPDTME--EAGHFGKHDKFFSLPKPPQA-----AEKDDKLSSHPELTRL 590
            ..||||..:.|.||::  |.|            :||::     ..||.:.|......|:
  Rat   497 ALLPETRGQTLKDTLQDLEQG------------QPPRSYKTAPQRKDVEASGRTSSARV 543

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	111/495 (22%)
CG7084	NP_001247235.2	MFS	184..542	CDD:119392	80/357 (22%)
Slc22a13	NP_001119757.1	2A0119	12..510	CDD:273328	118/524 (23%)
Slc22a13	NP_001119757.1	MFS	139..500	CDD:119392	83/370 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.020