DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7084 and CG3690

DIOPT Version :9

Sequence 1:	NP_001247235.2	Gene:	CG7084 / 42606	FlyBaseID:	FBgn0038938	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_001284764.1	Gene:	CG3690 / 31047	FlyBaseID:	FBgn0040350	Length:	558	Species:	Drosophila melanogaster

Alignment Length:	523	Identity:	110/523 - (21%)
Similarity:	185/523 - (35%)	Gaps:	156/523 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 GWSYDKTWYESTIPTDHNWVCAKDLFVTNVFVVGRVT---EVAGSFILGQMGDSYGRR---FVYY 204
            |..|:.:.....:|:..   |...|.:.:..::..:|   .::.:.:.|.:.|..|||   .|.|
  Fly    58 GTVYETSTMSYILPSAE---CDLKLSLLDKGILNAITYAGMISSAVLWGYLADIKGRRNLLIVGY 119

  Fly   205 ISVVFCSLGRLGSIMCTSSYTWFLIMSGIVGLTVNSLFQSPQIIGMEISREEDRSRIAFFQSCGW 269
            .:...|.||  |::  :.|....::...:.|..::..|........|:...:.|.||.......:
  Fly   120 AADTICVLG--GAL--SQSRIQLMVFKYLGGFCMSGPFAVLMTYLTELHGRKHRQRIMMMVGIMF 180

  Fly   270 SIGTTLMPLL-------YW----W---LRHWDSFMWLTSIPTAMVLLFSKYVIESPRWLISKQRF 320
            ||.|..:|.|       .|    |   |..|..|:.:|::|:.:..:...:..|||::|:||.|.
  Fly   181 SIATLTLPGLAMLILPETWNIQIWTLSLTSWQFFVAVTALPSLLSFVLFFFFPESPKFLMSKGRN 245

  Fly   321 REAI-------------------VQL---QKIAKINGHRFDMT-------EKELAEIYSRDKQDV 356
            |||:                   ::|   :.|..:..|..|.|       ..|..|:...:.||.
  Fly   246 REALDAFKFMYHLNSRKPKDSFPIKLLANEVIVPVKKHAKDETIPTELKLPTECVEVQDPENQDS 310

  Fly   357 TYGIASLFAGWRLAR---NTTIMGFSWCVVAVSYFTLV-----------LFSSRMAGNPFLNFL- 406
            ..  :||.:|:...|   ....:|.|..|..:::..|:           ||:|.   |.:.|.:
  Fly   311 KK--SSLRSGFTQLRPLFTKPYLGLSLWVYLLNFCVLLGQNTMRLWLPQLFASI---NEYENLMS 370

  Fly   407 ----YQSIVEIPAYVVGRYMGDTYGRRFTNSVSFLISFVTCLPIIVYSTDERY-ENLMIYLATFI 466
                ..||..|..|.|.|....      ..:|:.....|.|..||..||   | .||::..|.|:
  Fly   371 GESQSTSICNILEYSVNRTQSQ------LEAVTRNDPTVECHVIITPST---YTNNLIVAGAGFV 426

  Fly   467 KFLNALTFFTVNL--------------------------------------------------QC 481
            .::  |..|.|||                                                  ..
  Fly   427 AYM--LAGFLVNLVGVKLIMTSGLLIAAGCSIGMYWSSSAASTVALASLFVTMGSISATSVISAS 489

  Fly   482 LEIYPTCMRQTGVA-------LGTILANAIGVLAPYLVYLGTTVDIRAPYYILGVLFLLGGIGAL 539
            :.::||.:|...|:       ||::|.|   :..|.|:.||..    .|:.::....|.|...|.
  Fly   490 VSLFPTSLRTMIVSLEMMFGRLGSLLGN---IFFPALMGLGCV----PPFLMISAFMLAGCFMAA 547

  Fly   540 FLP 542
            |||
  Fly   548 FLP 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	110/523 (21%)
CG7084	NP_001247235.2	MFS	184..542	CDD:119392	102/480 (21%)
CG3690	NP_001284764.1	SP	42..549	CDD:273317	107/520 (21%)
		MFS	49..>195	CDD:119392	29/143 (20%)
		MFS	419..>550	CDD:119392	24/139 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100