DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7084 and Slc22a26

DIOPT Version :9

Sequence 1:	NP_001247235.2	Gene:	CG7084 / 42606	FlyBaseID:	FBgn0038938	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	XP_017173677.1	Gene:	Slc22a26 / 236149	MGIID:	2385316	Length:	553	Species:	Mus musculus

Alignment Length:	567	Identity:	140/567 - (24%)
Similarity:	260/567 - (45%)	Gaps:	84/567 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 FQALMEKAGNHGRYQTLYNFVFVGGLAFSGAMIYMNII----------LALNIPDHWCTVPGREN 88
            ||.|:...|:|||:|.|.       :||   ::..|:|          .|.|: .|.|.|...:|
Mouse     3 FQDLLNLVGSHGRFQILQ-------MAF---LLICNVITMPHVILENFTAANL-GHRCWVHIIDN 56

  Fly    89 -TN-------FSLEEWRDITLPKQADNRGRKTFSNCEMFQMNFSEITDWSAWNSNLTK-TTEACQ 144
             ||       .|.::...|::|..::.|..|    |..|......:..::...||:|: .||.|.
Mouse    57 DTNSNNNSGILSQDDLLRISIPLDSNLRPEK----CRRFVQPQWHLLQFNGSFSNMTEPDTEPCM 117

  Fly   145 NGWSYDKTWYESTIPTDHNWVC--------AKDLFVTNVFVVGRVTEVAGSFILGQMGDSYGRRF 201
            :||.||:..:.||..|:.|.||        ||.:|:..|        :||.|:.|.:.|.:||:.
Mouse   118 DGWVYDQRTFLSTTVTEWNLVCGSQELNSVAKFIFLIGV--------LAGHFVGGHLSDKFGRKL 174

  Fly   202 VYYISVVFCSLGRLG-SIMCTS-SYTWFL--IMSGIVGLTVNSLFQSPQIIGMEISREEDRSRIA 262
            ::.     |:|.::. :..||: :.|:|:  ::..:.||.:..:..:..::.:|.:..:.::.:.
Mouse   175 LFR-----CALLQMAITGTCTALAPTFFIYCLLRFLTGLCIIPINTNSVLLMLEWTSPKTQALVT 234

  Fly   263 FFQSCGWSIGTTLMPLLYWWLRHWDSFMWLTSIPTAMVLL-FSKYVIESPRWLISKQRFREAIVQ 326
            .........|..::..|.:..::|.......|:|..::|: .|:::.||.||||...:.::|:.:
Mouse   235 TLSMSSHHFGGLILAGLAFAFQNWHHLQLAISVPIFVLLIPTSRWLTESARWLIVTNKPQKALQE 299

  Fly   327 LQKIAKING--HRFDMTEKELAEIYSRDKQDVTY---GIASLFAGWRLARNTTIMGFSWCVVAVS 386
            |:|:|..||  :..|:...|:.....:|:..:..   .:..||....|.:..       |::.:.
Mouse   300 LRKVASKNGIKNSEDVLTMEVVRTIMKDEIAIPRTKPSLRDLFHMPNLRKRL-------CLLCLL 357

  Fly   387 YFTLV-------LFSSRMAGNPFLNFLYQSIVEIPAYVVGRYMGDTYGRRFTNSVSFLISFVTCL 444
            .|..:       :....:.||.||.....|...|||..:|.::.:..|||.:..:..|:..:..|
Mouse   358 RFLQISPTVGINMNLQHLKGNVFLTQSLTSAFSIPATALGGFLLNYIGRRISQLLPCLLFGIFLL 422

  Fly   445 PIIVYSTDERYENLMIYLATFIKFLNALTFFTVNLQCLEIYPTCMRQTGVALGTI-LANAIGVLA 508
            .|:  |..:..:.|::.|.|.....:|:.:.:..|...|:.||.:|.|  |||.| :...:|...
Mouse   423 SIV--SVPQEMQTLLVVLITLAGGSSAMIYNSNVLYSSELMPTVIRAT--ALGVIGICGGVGAAL 483

  Fly   509 PYLVYLGTTVDIRAPYYILGVLFLLGGIGALFLPETLHKKLPDTMEE 555
            ..|:.:.|......|:.|.|||.:|||:..|.||||.::.|||::::
Mouse   484 SPLIMILTLYSASLPWIIYGVLSILGGLLPLILPETKNQPLPDSIQD 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	128/532 (24%)
CG7084	NP_001247235.2	MFS	184..542	CDD:119392	85/375 (23%)
Slc22a26	XP_017173677.1	MFS	109..506	CDD:391944	98/420 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.100