Protein Alignment CG7084 and Slc22a8

DIOPT Version :10

• Sequence 1: NP_651016.1
• Gene: CG7084 / 42606
• FlyBaseID: FBgn0038938
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_112471.3
• Gene: Slc22a8 / 19879
• MGIID: 1336187
• Length: 537
• Species: Mus musculus
• Alignment Length: 587
• Identity: 155/587 - (26%)
• Similarity: 264/587 - (44%)
• Gaps: 81/587 - (13%)

  Fly    34 FQALMEKAGNHGRYQTLYNFVFVGGLAFSGAMIYMNI--ILALNIPDHWCTVPGRENTNFSLEEW 96
            |..::::.|:.|.:|.|:  |.:..|...|...: |:  |.....|||.|..|    .|.|||.|
Mouse     3 FSEILDRVGSMGPFQYLH--VTLLALPILGIANH-NLLQIFTATTPDHHCRPP----PNASLEPW 60

  Fly    97 RDITLPKQADNRGRKTFSNCEMFQMNFSEITDWSAWNSNLTKTTEACQNGWSYDKTWYESTIPTD 161
               .||...:.:..|    |    :.|..:.:.|..| :....||.|.:||.|:.|  ..||.|:
Mouse    61 ---VLPLGPNGKPEK----C----LRFVHLPNASLPN-DTQGATEPCLDGWIYNST--RDTIVTE 111

  Fly   162 HNWVC--------AKDLFVTNVFVVGRVTEVAGSFILGQMGDSYGRRFVYYISVVFCSLGRLGSI 218
            .:.||        |:.:|:..:.|        |..:.|::.|.:||:.:  ::..:..|...||.
Mouse   112 WDLVCGSNKLKEMAQSVFMAGILV--------GGPVFGELSDRFGRKPI--LTWSYLLLAASGSS 166

  Fly   219 MCTS-SYTWFLIMSGIVGLTVNSLFQSPQIIGME----ISREEDRSRIAFFQSCGWSIGTTLMPL 278
            ...| |.|.::|...:.|.:::.:..|..|:.:|    .:|....:.|.:   | ::||..::|.
Mouse   167 AAFSPSLTVYMIFRFLCGCSISGISLSTIILNVEWVPTSTRAISSTTIGY---C-YTIGQFILPG 227

  Fly   279 LYWWLRHWDSFMWLTSIPTAMVLLFSK---YVIESPRWLISKQRFREAIVQLQKIAKINGHRFDM 340
            |.:.:..|   .||....:|...:||.   :|.||.|||:...:|.:|:..||::|..||.:.:.
Mouse   228 LAYAVPQW---RWLQLSVSAAFFIFSLLSWWVPESIRWLVLSGKFSKALKTLQRVATFNGKKEEG 289

  Fly   341 TEKELAEIYSRDKQDVT-----YGIASLFAGWRLARNTTIMGFSWCVVAVSYFTLVLFSSRMAGN 400
            .:..:.|:....::|:|     ||::.||....|.|.|..:..:|.....:|::|.:.......|
Mouse   290 EKLTVEELKFNLQKDITSAKVKYGLSDLFRVSILRRVTFCLSLAWFATGFAYYSLAMGVEEFGVN 354

  Fly   401 PFLNFLYQSIVEIPAYVVGRYMGDTYGRRFTNSVSFLISFVTCLPIIVYSTDERYENLMIYLATF 465
            .::..:....|:|||..:........|||.|.....:::.|..|.:|..|::  .:.|...||.|
Mouse   355 IYILQIIFGGVDIPAKFITILSISYLGRRITQGFLLILAGVAILALIFVSSE--MQLLRTALAVF 417

  Fly   466 IKFLNALTFFTVNLQCLEIYPTCMRQTGVALGTILANAIGVLAPYLVYLGTTVDIRAPYYILGVL 530
            .|...:.:|..:.|...|:|||.:||||:.:..|.|....::|| ||.:...:....|..|.|.:
Mouse   418 GKGCLSGSFSCLFLYTSELYPTVLRQTGMGISNIWARVGSMIAP-LVKITGELQPFIPNVIFGTM 481

  Fly   531 FLLGGIGALFLPETLHKKLPDTMEEAGHFGKHDKFFSLPKPPQAAEKDDKLSSHPELTRLRRSET 595
            .||||..|.||.|||::.||:|:|:...:.:..|               |....||..  :.|:|
Mouse   482 TLLGGSAAFFLLETLNRPLPETIEDIQDWYQQTK---------------KTKQEPEAE--KASQT 529

  Fly   596 AP 597
            .|
Mouse   530 IP 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7084	NP_651016.1	MFS_SLC22	146..542	CDD:340875	110/416 (26%)
Slc22a8	NP_112471.3	2A0119	11..503	CDD:273328	145/532 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	513..537		7/36 (19%)