DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7084 and K09E9.1

DIOPT Version :9

Sequence 1:	NP_001247235.2	Gene:	CG7084 / 42606	FlyBaseID:	FBgn0038938	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_001368581.1	Gene:	K09E9.1 / 181654	WormBaseID:	WBGene00010724	Length:	518	Species:	Caenorhabditis elegans

Alignment Length:	508	Identity:	109/508 - (21%)
Similarity:	213/508 - (41%)	Gaps:	68/508 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 EWRD------ITLPKQADNRGRKTFSNCE-----MFQMNFSEITDWSAWNSNLTKTTEACQNGWS 148
            |.||      :|.|::   |.|:.|...|     :.|:.:..:.......:.:..:.|.|.....
Worm    32 EQRDDKGPLKLTEPRK---RMREDFGYYEIRLLVLTQLGYIPVAAAMLMTAFMEPSPEWCDTVRE 93

  Fly   149 YDKTWYES------TIPTDHNWVCAKDLFVTNVFVVGRVT--EVAGSFILGQMGDSYGRRFVYYI 205
            .:::|..:      ::..:..:.|.|:...|...:...:.  .:.|||:.|.:.|..||:.||..
Worm    94 TEQSWKLNPNNEFYSLSVERGFACQKNSNQTTAMMSSLLMWGALIGSFVCGFLSDRLGRKPVYLG 158

  Fly   206 SVVFCSLGRLGSIMCTSSY-TWFLIMSGI--VGLTVNSLFQSPQIIGMEISREEDRSRIAFFQSC 267
            .::..::|.:  ::..|.| :|..|.:.:  :|........:..:|..| :.|..:||:......
Worm   159 CLLMITIGHI--LLTFSMYLSWMTINATLAAMGFFCGGYMVTNFVILTE-AFELPKSRLLVVSLN 220

  Fly   268 GWSIGTTLMPLLYWWLRHWDSFMWLTSIPTAMVLLFSKYVI-ESPRWLISKQRFREAIVQLQKIA 331
            |||:...:..|...:..:|.::..:.:|..|.:.:.|.... ||.|||.:.....:|.....:|.
Worm   221 GWSVSMAVTALAASYTLNWYAYHTIFAIVGACIAIISLATCSESCRWLSANGLQNDAKKIALQIT 285

  Fly   332 KINGHRFDMTEKEL------------AEIYSRDKQDVTYGIASLFAGWRLARNTTIMGFSWCVVA 384
            .:|.:| |:.|.::            |..::.:|:  |:  .:||...|..:.|.:|.:|:...:
Worm   286 LLNNNR-DIEEDDISILSWHEILGFSAPTHTDEKK--TW--KTLFKSTRFLKPTAVMCYSFMASS 345

  Fly   385 VSYFTLVLFSSRMAGNPFLNFLYQSIVEIPAYVVGRYMGDTYGRRFTNSVSFLISFV--TCLPII 447
            :..|........:.||.:.|   .:|:.|..:::|  ....:..||....:..||.|  .||..:
Worm   346 IVSFGFYFSIDVLPGNRYYN---MTIMGILKFILG--FTPFFLNRFLTKRAIAISSVGLCCLAAL 405

  Fly   448 VYSTDERYE-NLMIYLATFIKFLNAL----TFFTVNLQCLEIYPTCMRQTGVALGTILANAIG-- 505
            :....:.|: ..|.::...:..:.|.    |:...:|...|::||.:|  .:|.|  :.||.|
Worm   406 MILPIQYYDIQCMRWVIIMLSLMIAAGIDPTWKINHLYSAELFPTSVR--SMARG--VCNAGGRL 466

  Fly   506 --VLAPYLVYLGTTVDIRAPYYILGV-LFLLGGIGALFLPETLHKKLPDTMEE 555
              |:||.:||| .|.....|..|..| ||:...:..:|||:...|...:..:|
Worm   467 GSVMAPMIVYL-RTFGFFIPNAIFAVLLFIQLVVIVIFLPDDSDKDANEMNDE 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	108/503 (21%)
CG7084	NP_001247235.2	MFS	184..542	CDD:119392	89/385 (23%)
K09E9.1	NP_001368581.1	MFS	98..505	CDD:421695	93/424 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010